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Diethylaminoethyltrimethylazepinone

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Identification
Molecular formula
C15H26N2O
CAS number
10200-61-4
IUPAC name
1-[2-(diethylamino)ethyl]-3,5,7-trimethyl-3H-azepin-2-one
State
State

At room temperature, it exists as a liquid.

Melting point (Celsius)
-5.00
Melting point (Kelvin)
268.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
238.34g/mol
Molar mass
238.3440g/mol
Density
1.0187g/cm3
Appearence

This compound typically appears as a colorless to pale yellow liquid.

Comment on solubility

Solubility of 1-[2-(diethylamino)ethyl]-3,5,7-trimethyl-3H-azepin-2-one

The solubility of 1-[2-(diethylamino)ethyl]-3,5,7-trimethyl-3H-azepin-2-one can be influenced by several factors, including its molecular structure and the surrounding medium. This particular compound, featuring both hydrophobic and hydrophilic components, may exhibit varying solubility in different solvents. Here are a few points to consider:

  • Polar Solvents: The presence of diethylamino groups may enhance solubility in polar solvents such as water or alcohols due to hydrogen bonding.
  • Nonpolar Solvents: Conversely, the trimethyl groups suggest a tendency for lipophilicity, which may lead to better solubility in nonpolar solvents like hexane or chloroform.
  • Temperature Effects: Solubility is also temperature-dependent; generally, an increase in temperature can increase solubility in most solvents.
  • pH Influence: The pH of the solution can affect the ionization of the amine group, further modifying solubility characteristics.

Overall, it’s vital to perform experimental assessments to accurately characterize the solubility behavior of this compound. As noted, the solubility may also vary based on concentration, leading to phenomena such as saturation and precipitation at higher concentrations.

Interesting facts

Interesting Facts about 1-[2-(diethylamino)ethyl]-3,5,7-trimethyl-3H-azepin-2-one

This compound, belonging to the azepine family, is quite noteworthy for several reasons. It represents a fascinating intersection of medicinal chemistry and synthetic organic chemistry.

Key Characteristics:

  • Pharmacological Potential: Compounds like this one are often studied for their potential as therapeutic agents. The structural features may impart unique biological activities that can be further explored in drug design.
  • Synthetic Versatility: The diethylamino group is a common motif in various pharmaceuticals, and its presence here opens up pathways for synthesis and derivatization leading to new compounds.
  • Structural Diversity: With trimethyl substitutions on the azepine ring, this compound showcases how small changes in the molecular structure can lead to significant variations in chemical behavior and properties.

As noted by researchers, "the complexity of azepine structures offers a canvas for innovative pharmacological applications." This type of molecule might very well serve as a lead compound in the development of new medications. Its unique architecture makes it a subject of interest in understanding how structural configuration influences activity.

Research Significance:

  • Structure-Activity Relationship (SAR): Scientists often conduct SAR studies on compounds like this to determine how changes in structure affect biological potency and selectivity.
  • Biochemical Assays: Ongoing research may utilize in vitro and in vivo assays to elucidate the compound's mechanism of action and underlying biochemical pathways.
  • Innovation in Medicinal Chemistry: As new derivatives are synthesized, the potential for novel therapeutic agents continues to expand.

In summary, 1-[2-(diethylamino)ethyl]-3,5,7-trimethyl-3H-azepin-2-one not only exemplifies the intricate world of chemical structures but also embodies the ongoing quest for new medical discoveries. Its study may reveal invaluable insights that could lead to the next breakthrough in pharmaceuticals.

Synonyms
1900-32-9
1-[2-(diethylamino)ethyl]-3,5,7-trimethyl-1,3-dihydro-2H-azepin-2-one
NSC135361
DTXSID00274562
AKOS024321401
NSC-135361