Skip to main content

Primidone

ADVERTISEMENT
Identification
Molecular formula
C12H14N2O2
CAS number
125-33-7
IUPAC name
1-[2-(diethylamino)ethyl]-5-ethyl-5-phenyl-hexahydropyrimidine-2,4,6-trione
State
State

Primidone is in a solid crystalline state at room temperature.

Melting point (Celsius)
279.00
Melting point (Kelvin)
552.15
Boiling point (Celsius)
237.50
Boiling point (Kelvin)
510.60
General information
Molecular weight
218.26g/mol
Molar mass
218.2590g/mol
Density
1.1450g/cm3
Appearence

Primidone appears as a white crystalline powder. It is typically odorless and exhibits no notable color variations when pure.

Comment on solubility

Solubility of 1-[2-(diethylamino)ethyl]-5-ethyl-5-phenyl-hexahydropyrimidine-2,4,6-trione

The solubility characteristics of the compound 1-[2-(diethylamino)ethyl]-5-ethyl-5-phenyl-hexahydropyrimidine-2,4,6-trione can be quite intriguing due to its unique structure. This compound may exhibit solubility behavior influenced by several factors including:

  • Polarity: The presence of functional groups like the diethylamino moiety suggests that it could be relatively polar, which might enhance its solubility in polar solvents such as water and methanol.
  • Hydrophobic Interactions: The phenyl and ethyl groups in its structure contribute hydrophobicity, possibly resulting in lower solubility in highly polar solvents.
  • pH Dependency: The ionization of the diethylamino group at different pH levels can alter solubility, making it more soluble in acidic conditions where the group may become protonated.
  • Temperature Effects: Increased temperature generally leads to increased solubility for most compounds, which might apply to this one as well.

In summary, while predicting the exact solubility of this compound without empirical data may be challenging, one can anticipate that the interplay between its polar and nonpolar characteristics will shape its solubility profile in various solvents. Further studies, including experimental solubility testing, would provide deeper insights into its behavior in solution.

Interesting facts

Interesting Facts about 1-[2-(diethylamino)ethyl]-5-ethyl-5-phenyl-hexahydropyrimidine-2,4,6-trione

This fascinating compound belongs to the class of pyrimidine derivatives, which are known for their diverse biological activities. Pyrimidines are essential building blocks in biochemistry, playing critical roles in the structure of nucleotides and nucleic acids. The unique structure of this compound specifically contributes to its potential applications in medicinal chemistry. Here are some engaging aspects:

  • Pharmacological Potential: Compounds like this one have attracted attention due to their ability to interact with various biological targets, such as enzymes and receptors. This highlights their potential for developing new pharmaceuticals.
  • Structure-Activity Relationship: The presence of the diethylamino group is noteworthy. This moiety is known to influence the lipophilicity and overall pharmacokinetic properties of the compound, potentially enhancing its efficacy.
  • Research Applications: Researchers often explore compounds with similar structures for their potential roles in treating neurological disorders or as anti-inflammatory agents, demonstrating the compound's significance in contemporary scientific investigations.

Moreover, the structural complexity of this compound opens avenues for synthetic modifications that can fine-tune its therapeutic effects. As quoted by chemists, “Diversity in chemical structure leads to diversity in function.” This compound is a perfect example of how variations can lead to innovative solutions in drug discovery.

In summary, the exploration of 1-[2-(diethylamino)ethyl]-5-ethyl-5-phenyl-hexahydropyrimidine-2,4,6-trione offers not just a glimpse into the frontier of medicinal chemistry but also an appreciation for the intricate relationship between structure and function in biological systems.