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Methoxetamine

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Identification
Molecular formula
C15H21NO2
CAS number
1239943-76-0
IUPAC name
1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol
State
State

At room temperature, Methoxetamine is generally found as a solid.

Melting point (Celsius)
201.50
Melting point (Kelvin)
474.65
Boiling point (Celsius)
372.80
Boiling point (Kelvin)
645.95
General information
Molecular weight
265.35g/mol
Molar mass
265.3870g/mol
Density
1.0052g/cm3
Appearence

Methoxetamine typically appears as a white crystalline powder.

Comment on solubility

Solubility of 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol

The solubility of the compound 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol, with the chemical formula C15H21NO2, is a multifaceted topic influenced by various factors. This compound's structure suggests potential for differing solubility behaviors in various solvents. Below are some key points regarding its solubility:

  • Polar Solvents: The presence of the dimethylamino group may enhance solubility in polar solvents such as water, due to its ability to form hydrogen bonds.
  • Non-Polar Solvents: Conversely, the cyclohexanol and aromatic components can increase solubility in non-polar or less polar solvents like chloroform or hexane.
  • Temperature Dependence: The solubility may vary significantly with temperature, where increased temperatures often lead to higher solubility for many organic compounds.
  • pH Sensitivity: The pH of the solution could also play a crucial role, especially due to the basic nature of the dimethylamino group, which may protonate and affect solubility.

In summary, the solubility of 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol can be understood as highly dynamic, depending on the environmental conditions. Therefore, experimentation is often necessary to determine its precise solubility characteristics in a given solvent.

Interesting facts

Interesting Facts about 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol

This intriguing compound is part of a broader class of chemicals that exhibit a range of biological activities. Here are some fascinating insights into its structure and potential applications:

  • Pharmacological Potential: The compound has been studied for its potential use in pharmaceuticals, particularly due to the presence of the dimethylamino group, which often enhances solubility and bioavailability in drug design.
  • Cyclohexanol Framework: The cyclohexanol moiety contributes to the compound’s three-dimensional structure, influencing its interaction with biological targets. This structural feature can provide unique properties compared to linear analogs.
  • Substituents Matter: The 4-methoxy phenyl group not only modifies the chemical reactivity but can also enhance the efficacy of the compound by increasing lipophilicity, making it more likely to cross biological membranes.
  • Research Interest: Researchers are particularly interested in analogs of this compound for their potential role as cognitive enhancers or in treating neurodegenerative disorders, as many compounds with similar structures have shown promise in preclinical studies.
  • Synergistic Effects: The combination of the dimethylamino and the methoxyphenyl functionalities can lead to synergistic effects that may enhance therapeutic outcomes in a medicinal chemistry context.

As scientists continue to explore the landscape of organic compounds, 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol represents a compelling opportunity for further investigation into its mechanism of action and potential medicinal uses.

Synonyms
venlafaxine
93413-69-5
D,L-Venlafaxine
Venlafaxina
Elafax
Venlafaxinum
Efectin
1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)cyclohexanol
velafax
Venlafaxinum [INN-Latin]
Venlafexine
Kanghong
Trevilor
Venlafaxina [INN-Spanish]
Venlor
1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol
1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol
GRZ5RCB1QG
UNII-GRZ5RCB1QG
NSC-758676
Venlafaxine (INN)
CHEBI:9943
DTXSID6023737
HSDB 6699
DTXCID403737
Cyclohexanol, 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]-
EC 618-944-2
NSC 758676
Venlafaxine [INN:BAN]
NCGC00095109-01
N,N-dimethyl-2-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl)ethylamine
VENLAFAXINE [INN]
Cyclohexanol, 1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)-, (+-)-
Venlafaxinum (INN-Latin)
Venlafaxina (INN-Spanish)
Venlafaxin
Efectin (TN)
CAS-93413-69-5
SR-01000762930
DL-Venlafaxine
CYCLOHEXANOL, 1-(2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL)-
Spectrum_001671
SpecPlus_000842
VENLAFAXINE [MI]
Spectrum2_000542
Spectrum3_000989
Spectrum4_001115
Spectrum5_001516
CHEMBL637
VENLAFAXINE [VANDF]
SCHEMBL35154
BSPBio_002657
KBioGR_001590
KBioSS_002151
VENLAFAXINE [WHO-DD]
MLS006011859
DivK1c_006938
SPECTRUM1504171
SPBio_000583
GTPL7321
BDBM82071
KBio1_001882
KBio2_002151
KBio2_004719
KBio2_007287
KBio3_001877
N06AX16
HMS1922F05
HMS2090F04
HMS2093A12
HMS3714K11
HMS3886K14
Pharmakon1600-01504171
1-{2-(dimethylamino)-1-[4-(methyloxy)phenyl]ethyl}cyclohexanol
HY-B0196
Tox21_111425
CCG-39577
NSC_62923
NSC758676
s5655
STK621394
AKOS005555049
Tox21_111425_1
AC-1547
DB00285
FV28676
SDCCGSBI-0052740.P003
NCGC00095109-02
NCGC00095109-03
NCGC00095109-04
NCGC00095109-05
NCGC00095109-06
NCGC00095109-08
NCGC00095109-20
AS-76254
SMR002204138
WY-45655
SBI-0052740.P002
CAS_93413-69-5
CAS_99300-78-4
DB-057399
DB-226024
NS00000031
C07187
D08670
D82446
EN300-708795
AB00053751-08
AB00053751-10
AB00053751-11
AB00053751_12
AB00053751_13
Q898407
SR-01000762930-3
SR-01000762930-4
BRD-A51714012-001-02-3
BRD-A51714012-003-01-1
BRD-A51714012-003-12-8
BRD-A51714012-003-13-6
1-[2-dimethylamino-1-(4-methoxylphenyl)ethyl]cyclohexanol
(RS)-1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol
(+/-)-1-(alpha-((DIMETHYLAMINO)METHYL)-P-METHOXYBENZYL)CYCLOHEXANOL
(+/-)-1-(.ALPHA.-((DIMETHYLAMINO)METHYL)-P-METHOXYBENZYL)CYCLOHEXANOL
1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol;(+/-)-Venlafaxine;Trevilor
540726-98-5