Ketorolac | Solubility of Things

Identification

Molecular formula

C₁₅H₁₃NO₂

CAS number

74103-06-3

IUPAC name

[1-[2-(dimethylamino)propyl]pyrrol-2-yl]-phenyl-methanone

State

Ketorolac is typically found in a solid state at room temperature. It is a stable compound under normal conditions and is usually available in tablet or injectable form for medical applications.

Melting point (Celsius)

164.00

Melting point (Kelvin)

437.15

Boiling point (Celsius)

544.20

Boiling point (Kelvin)

817.35

General information

Molecular weight

255.27g/mol

Molar mass

255.2730g/mol

Density

1.2116g/cm³

Appearence

Ketorolac appears as a white to off-white crystalline powder. It is known for its distinctive odor that can be noted at room temperature.

Comment on solubility

Solubility of [1-[2-(dimethylamino)propyl]pyrrol-2-yl]-phenyl-methanone

The solubility of the compound [1-[2-(dimethylamino)propyl]pyrrol-2-yl]-phenyl-methanone, a complex organic molecule, is influenced by several factors including its structural composition and the presence of functional groups. Generally, such compounds can exhibit diverse solubility behaviors in different solvents. Here are some key points regarding its solubility:

Polar vs. Nonpolar Solvents: The presence of the dimethylamino group introduces polar characteristics, which may enhance solubility in polar solvents like water or alcohols.
Alkyl Chain Influence: The alkyl chain from the dimethylamino group may promote some degree of hydrophobic interactions, suggesting a potential partial solubility in nonpolar solvents such as hexane.
Crystallinity: If the compound tends to crystallize, this can significantly affect its overall solubility characteristics.
Temperature Dependence: Solubility can increase with temperature; therefore, higher temperatures might yield better solubility outcomes.

In conclusion, while specific solubility data might be limited, understanding the balance of polar and nonpolar elements in the compound's structure is crucial for predicting its behavior in different solvent systems. As a general *rule of thumb*, "like dissolves like," thus one can anticipate that this compound will be more soluble in solvents that possess similar polar characteristics.

Interesting facts

Interesting Facts about 1-[2-(dimethylamino)propyl]pyrrol-2-yl]-phenyl-methanone

This intriguing compound is gaining attention in various fields of research, particularly in medicinal chemistry and pharmacology. Some key points about this compound include:

Pharmacological Potential: The structural characteristics of this compound suggest it may possess interesting pharmacological properties, particularly as a potential molecular probe for studying neurotransmitter systems.
Dimethylamino Group: The presence of the dimethylamino group enhances the compound's ability to interact with biological systems, making it a candidate for the exploration of new therapeutic agents.
Pyrrol-2-yl Functionality: The pyrrolidine ring structure is significant due to its occurrence in numerous natural products and alkaloids, which are often associated with various biological activities.
Applications: Due to its unique structure, it could potentially be investigated for applications in drug development, particularly in the domains of anxiety and depression treatment, or cognitive enhancers.
Analytical Studies: The compound may also serve as a valuable subject for chemical analysis, assisting in the development of analytical techniques and helping in the understanding of complex biochemical pathways.

As researchers continue to explore the vast landscape of chemical compounds, the study of 1-[2-(dimethylamino)propyl]pyrrol-2-yl]-phenyl-methanone could unveil novel insights into the mechanisms of action and expand our knowledge of pharmacological agents.