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1-(2-ethylsulfonylethyl)-2-methyl-4-nitro-imidazole

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Identification
Molecular formula
C8H13N3O4S
CAS number
16087-24-2
IUPAC name
1-(2-ethylsulfonylethyl)-2-methyl-4-nitro-imidazole
State
State

At room temperature, 1-(2-ethylsulfonylethyl)-2-methyl-4-nitro-imidazole exists in a solid state. It is generally stable under normal conditions.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
422.00
Boiling point (Kelvin)
695.15
General information
Molecular weight
233.27g/mol
Molar mass
233.2700g/mol
Density
1.4300g/cm3
Appearence

This compound is typically a solid at room temperature. It appears as a crystalline powder, which could range from off-white to slightly yellow in color, owing to the nitro group presence.

Comment on solubility

Solubility of 1-(2-ethylsulfonylethyl)-2-methyl-4-nitro-imidazole

The solubility of 1-(2-ethylsulfonylethyl)-2-methyl-4-nitro-imidazole can be influenced by several factors, which are fundamental to understanding its behavior in various solvents. Here are key points regarding its solubility:

  • Polarity: The presence of the ethylsulfonyl and nitro groups contributes to the overall polarity of the compound, which may enhance its solubility in polar solvents such as water.
  • Temperature: Like many organic compounds, solubility often increases with temperature. Warmer temperatures can help dissolve 1-(2-ethylsulfonylethyl)-2-methyl-4-nitro-imidazole more readily.
  • pH Levels: The pH of the solution can impact the ionization of functional groups within the compound, further affecting solubility. Acidic or basic conditions could potentially enhance solubility.
  • Concentration: In concentrated solutions, solubility can be limited due to interactions between solute molecules, leading to precipitation.

In conclusion, while 1-(2-ethylsulfonylethyl)-2-methyl-4-nitro-imidazole shows certain solubility characteristics due to its structural components, it is essential to consider the combination of factors like polarity, temperature, pH, and concentration to fully understand its solubility profile. As with many chemical compounds, experimentation may be required to identify the most effective solvents for optimal solubility.

Interesting facts

Interesting Facts About 1-(2-Ethylsulfonylethyl)-2-methyl-4-nitro-imidazole

1-(2-ethylsulfonylethyl)-2-methyl-4-nitro-imidazole is a fascinating compound known for its diverse applications and importance in medicinal chemistry. Here are some interesting aspects of this compound:

  • Pharmaceutical Relevance: This compound belongs to the class of imidazole derivatives, which are frequently explored in the development of pharmaceuticals. Imidazoles like this one can exhibit various biological activities, including antimicrobial, anti-inflammatory, and even antitumor properties.
  • Structural Significance: The presence of both a nitro group and a sulfonyl group in its structure introduces interesting electronic properties. The nitro group can enhance the compound's ability to interact with biological targets, making it an important structural motif in drug synthesis.
  • Solubility and Activity: Sulfonyl groups are known to improve the aqueous solubility of organic molecules, which is a vital characteristic for drug candidates as it can influence their bioavailability and overall efficacy.
  • Synthesis and Modification: The synthetic pathways for producing this compound can lead to variations in its structure, allowing chemists to explore a library of derivatives for enhanced activity against specific targets. This trait demonstrates the beauty of organic synthesis, where small changes can lead to significant differences in function.
  • Future Research Potential: The continued investigation into imidazole derivatives has the potential for discovering new therapeutic agents. The unique combination of functional groups within this compound could unlock novel pathways for treating various diseases.

In summary, the 1-(2-ethylsulfonylethyl)-2-methyl-4-nitro-imidazole compound represents a critical intersection of structural chemistry and pharmacology. Its varied chemical properties and potential therapeutic benefits make it a compound of interest in ongoing scientific research.

Synonyms
25459-12-5
1H-Imidazole, 1-(2-(ethylsulfonyl)ethyl)-2-methyl-4-nitro-
1-(2-ethylsulfonylethyl)-2-methyl-4-nitroimidazole
Isotinidazole
1-(2-(Ethylsulfonyl)ethyl)-2-methyl-4-nitro-1H-imidazole
4-Nitro-5-desnitro Tinidazole
OTU3H1J2L2
1-[2-(ethylsulfonyl)ethyl]-2-methyl-4-nitro-1H-imidazole
Tinidazole EP Impurity B
Tinidazole Impurity B
UNII-OTU3H1J2L2
Oprea1_106915
SCHEMBL28879382
DTXSID20180131
ISOTINIDAZOLE [USP IMPURITY]
STL334630
AKOS022124900
TINIDAZOLE IMPURITY B [EP IMPURITY]
1-(2-ethylsulfonyl-ethyl)-2-methyl-nitroimidazole