No common name available | Solubility of Things

Identification

Molecular formula

C₂₅H₂₄FNO₂

CAS number

IUPAC name

1-(2-fluorophenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one

State

At room temperature, this compound is typically found in a solid state and is stable under standard conditions of temperature and pressure. It can decompose when exposed to high temperatures or reactive chemicals.

Melting point (Celsius)

112.00

Melting point (Kelvin)

385.15

Boiling point (Celsius)

590.00

Boiling point (Kelvin)

863.15

General information

Molecular weight

363.41g/mol

Molar mass

363.4120g/mol

Density

1.2000g/cm³

Appearence

This compound generally appears as a crystalline solid with a pale yellow to off-white coloration. Its appearance may vary based on its purity and the presence of impurities.

Comment on solubility

Solubility of 1-(2-fluorophenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one

The solubility of 1-(2-fluorophenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one is influenced by its structural components and molecular interactions. This compound features several functional groups that impact its ability to dissolve in various solvents. Here are some key points to consider regarding its solubility:

Solvent Polarity: The solubility of this compound may vary significantly depending on the polarity of the solvent used. Generally, organic solvents such as dimethyl sulfoxide (DMSO) or ethanol can facilitate better solubility due to their compatibility with the organic groups within the molecule.
Hydrogen Bonding: The presence of -O- (ether) and -NH- (amine) groups suggests potential for hydrogen bonding, which may enhance solubility in polar solvents.
Molecular Weight and Size: With a relatively high molecular weight, solubility may decrease in less polar or non-polar solvents due to increased hydrophobic interactions, making it essential to select an appropriate solvent system.
Conformational Flexibility: The presence of cyclic moieties may lead to steric hindrance, which could affect how the compound interacts with solvent molecules, further impacting solubility.
Practical Applications: Understanding the solubility of this compound is crucial for applications in drug formulation, as it can dictate bioavailability and the feasibility of various therapeutic uses.

In conclusion, the solubility of 1-(2-fluorophenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one is multifaceted, influenced by a range of factors including functional group interactions, solvent choice, and molecular structure. Therefore, careful consideration is required when determining optimal conditions for dissolution.

Interesting facts

Interesting Facts about 1-(2-Fluorophenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one

This fascinating compound belongs to the class of chalcones, which are known for their unique structural features that make them prominent in biological fields. Here are some intriguing insights regarding this compound:

Potential Pharmaceutical Applications: Compounds like this have shown promise in medicinal chemistry. Chalcones exhibit properties such as anti-inflammatory, antimicrobial, and even anticancer activities, making them a focal point for drug discovery research.
Diverse Bioactivity: The presence of various functional groups, such as the fluorophenyl and pyrrolidin-1-ylethoxy, suggests the potential for an array of biological activities. This diversity can lead to interactions with different biological pathways.
Synthesis and Derivitization: The versatility in the synthesis of chalcones allows for numerous derivatives. Scientists can modify existing chalcone structures to enhance their biological efficacy or decrease toxicity, tailoring them for specific therapeutic uses.
Study of Structure-Activity Relationship (SAR): Researching such compounds can unveil the significance of each substituent on the molecule. Understanding how changes affect biological activity can lead to innovative drug design.

Chalcone derivatives like 1-(2-fluorophenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one highlight the intricate relationship between chemical structure and biological function. "The beauty of chemistry lies in its ability to create complexity from simplicity," says many a chemist, signifying the endless possibilities that stem from the modification of a single molecular framework.

In conclusion, the exploration of this compound may very well contribute to significant advances in the realms of pharmaceuticals and material sciences, making it a critical subject of study for chemists and researchers alike.