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1-(2-hydroxy-1-methyl-indol-3-yl)iminoisothiourea

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Identification
Molecular formula
C11H13N3OS
CAS number
55634-91-0
IUPAC name
1-(2-hydroxy-1-methyl-indol-3-yl)iminoisothiourea
State
State

The compound is typically in a solid state at room temperature. It is usually presented as a powder or crystalline solid suitable for storage and handling in ambient conditions.

Melting point (Celsius)
289.00
Melting point (Kelvin)
562.15
Boiling point (Celsius)
379.00
Boiling point (Kelvin)
652.15
General information
Molecular weight
221.31g/mol
Molar mass
221.2960g/mol
Density
1.4300g/cm3
Appearence

1-(2-hydroxy-1-methyl-indol-3-yl)iminoisothiourea appears as an off-white to light brownish solid. It tends to be slightly hygroscopic, absorbing moisture from the atmosphere, and is generally supplied in powder or crystalline form.

Comment on solubility

Solubility of 1-(2-hydroxy-1-methyl-indol-3-yl)iminoisothiourea

The solubility of 1-(2-hydroxy-1-methyl-indol-3-yl)iminoisothiourea is a critical aspect that influences its application in various chemical processes. Here are some key points regarding its solubility:

  • Solvent Interaction: This compound is expected to have variable solubility in polar solvents due to the presence of functional groups such as hydroxyl and imino moieties, which can form hydrogen bonds.
  • pH Dependence: The solubility may be affected by the pH of the solution, as the ionization of the imino group can alter solubility behavior. Generally, solutions that provide a suitable pH environment will enhance solubility.
  • Temperature Factors: Increased temperature often enhances solubility for most organic compounds, and this may also apply here; therefore, solubility studies at different temperatures could yield valuable insights.

Overall, the solubility of 1-(2-hydroxy-1-methyl-indol-3-yl)iminoisothiourea can be characterized as moderate, where experimental conditions such as solvent choice and temperature play pivotal roles in determining its solubility profile.

Interesting facts

Interesting Facts about 1-(2-hydroxy-1-methyl-indol-3-yl)iminoisothiourea

The compound 1-(2-hydroxy-1-methyl-indol-3-yl)iminoisothiourea is a fascinating molecule that has garnered interest in the field of medicinal chemistry. Here are some key aspects that highlight its significance:

  • Biological Activity: This compound has shown potential as a bioactive agent, particularly in the realm of pharmacology. It is explored for its antiproliferative effects, making it a candidate for cancer research.
  • Structural Features: The structure of this compound features an indole ring, which is noteworthy for its role in various biological systems. Indoles are known for their presence in many natural products and pharmaceuticals.
  • Therapeutic Potential: Researchers are investigating how this compound might be utilized in the treatment of conditions such as diabetes and hypertension, owing to its unique interactions with biological targets.
  • Versatile Chemistry: The iminoisothiourea moiety provides opportunities for further chemical modifications, which can lead to the discovery of new derivatives with enhanced properties.
  • Complexity and Synthesis: Synthesizing this compound can be a complex process, often requiring multi-step organic reactions. This aspect can be both challenging and rewarding for chemists.

In summary, 1-(2-hydroxy-1-methyl-indol-3-yl)iminoisothiourea is a compound that exemplifies the intersection of complex organic chemistry and potential therapeutic application. Its unique structure and biological implications make it a compelling subject for ongoing research.