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Foscarnet Sodium

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Identification
Molecular formula
C9H13N3O7P
CAS number
63585-09-1
IUPAC name
1-(2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-5-methyl-pyrimidine-2,4-dione
State
State
The compound is typically in a crystalline form at room temperature.
Melting point (Celsius)
89.50
Melting point (Kelvin)
362.65
Boiling point (Celsius)
150.80
Boiling point (Kelvin)
423.95
General information
Molecular weight
250.09g/mol
Molar mass
152.0040g/mol
Density
2.1040g/cm3
Appearence

Foscarnet is a white crystalline powder. It is generally solid at room temperature and used as a trisodium salt for pharmaceutical purposes.

Comment on solubility

Solubility of 1-(2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-5-methyl-pyrimidine-2,4-dione (C9H13N3O7P)

The solubility of this compound exhibits some intriguing characteristics due to its complex structure. Several factors can influence solubility, including molecular polarity, presence of functional groups, and the overall molecular architecture. Below are key insights related to the solubility of this compound:

  • Polarity: The presence of polar functional groups such as hydroxyl (-OH) and carbonyl (C=O) plays a crucial role in solubility, often enhancing the compound's ability to dissolve in polar solvents such as water.
  • Intermolecular Interactions: The ability to form hydrogen bonds and dipole-dipole interactions can increase solubility in various solvents.
  • Solvent Compatibility: This compound may have better solubility in organic solvents, particularly those that can engage in favorable interactions with its large, organic framework.
  • Concentration Effects: At higher concentrations, solubility may decrease due to saturation or the formation of precipitates.

As a general rule, like dissolves like, meaning that polar compounds tend to dissolve well in polar solvents, while non-polar compounds prefer non-polar environments. For this compound, it is essential to approach solubility testing with a strategic focus on solvent choice and environmental conditions. Overall, the intricate balance between these factors dictates the solubility behavior of 1-(2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-5-methyl-pyrimidine-2,4-dione.

Interesting facts

Interesting Facts about 1-(2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-5-methyl-pyrimidine-2,4-dione

This compound, known for its complex structure, showcases the fascinating world of organic chemistry and phosphorus-containing compounds. Below are some intriguing aspects:

  • Structural Diversity: The molecule features a unique combination of a pyrimidine ring and a dioxaphosphinin moiety, which contributes to its potential reactivity and biological activity.
  • Phosphorus Chemistry: The presence of phosphorus in its structure highlights its significance in various biochemical pathways, especially in the synthesis of nucleotides and nucleic acids.
  • Potential Applications: Compounds like this are often explored for their utility in pharmaceuticals. They may act as enzyme inhibitors or modulators, providing pathways for new therapeutic agents.
  • Intriguing Synthesis: The synthesis of such a complex compound requires advanced organic synthetic techniques, often involving multi-step reactions and careful control of conditions.
  • Research Interest: This class of compounds is of great interest in medicinal chemistry, as researchers aim to discover new drugs that can leverage the unique properties of these nitrogen and phosphorus-containing organic molecules.

As we delve deeper into the realm of complex compounds, it is crucial to appreciate the intricate dance of atoms and bonds that result in molecules with rich chemical behavior. As one researcher aptly put it, “Each molecule tells a story of its elemental ancestors.” This compound certainly exemplifies that, weaving together elements of nitrogen, carbon, oxygen, and phosphorus into a narrative full of potential and discovery.

Synonyms
DTXSID90863848
CHEBI:182671
NS00015201
Thymidine-3',5'-cyclic monophosphate sodium salt
Thymidine-3',5'-cyclic monophosphate sodium salt
1-(2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-uro[3,2-d][1,3,2]dioxaphosphinin-6-yl)-5-methylpyrimidine-2,4-dione
1-(2-Hydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-5-methylpyrimidine-2,4(1H,3H)-dione