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Piribedil

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Identification
Molecular formula
C16H24N2O2
CAS number
3605-01-4
IUPAC name
1-[2-hydroxy-4-[2-(1-piperidyl)ethoxy]phenyl]butan-1-one
State
State

At room temperature, Piribedil is a solid.

Melting point (Celsius)
91.10
Melting point (Kelvin)
364.25
Boiling point (Celsius)
465.30
Boiling point (Kelvin)
738.45
General information
Molecular weight
298.38g/mol
Molar mass
298.3960g/mol
Density
1.2260g/cm3
Appearence

Piribedil typically appears as a white or off-white crystalline powder.

Comment on solubility

Solubility of 1-[2-hydroxy-4-[2-(1-piperidyl)ethoxy]phenyl]butan-1-one

Understanding the solubility of 1-[2-hydroxy-4-[2-(1-piperidyl)ethoxy]phenyl]butan-1-one is crucial for its applications in various fields. This compound, due to its complex structure, exhibits unique solubility characteristics:

  • Solvent Compatibility: It tends to be soluble in polar organic solvents such as ethanol and methanol, but less soluble in non-polar solvents. This suggests a strong interaction with polar molecular environments.
  • Temperature Dependence: The solubility of this compound may increase with temperature, meaning that heat could facilitate its dissolution, a typical behavior for many organic compounds.
  • pH Influence: The presence of the hydroxy group can lead to pH-dependent solubility, potentially increasing its solubility in acidic environments where protonation may occur.
  • Hydrogen Bonding: The ability of this compound to engage in hydrogen bonding enhances its solubility in water to some extent, though it is not primarily a water-soluble compound.

To summarize, the solubility of 1-[2-hydroxy-4-[2-(1-piperidyl)ethoxy]phenyl]butan-1-one can be influenced by a variety of factors, including solvent type, temperature, pH level, and the presence of functional groups that promote intermolecular interactions. As a result, the compound can demonstrate varied solubility profiles depending on the context in which it is used.

Interesting facts

Interesting Facts about 1-[2-hydroxy-4-[2-(1-piperidyl)ethoxy]phenyl]butan-1-one

This compound, often recognized for its complex structure, is an intriguing target for researchers in the field of medicinal chemistry. With its unique arrangement of functional groups, 1-[2-hydroxy-4-[2-(1-piperidyl)ethoxy]phenyl]butan-1-one showcases some fascinating properties and potential applications.

Key Characteristics

  • Pharmacological Interest: This compound is studied for its potential role in developing therapeutic agents, particularly in neurological and psychiatric conditions due to its piperidine moiety.
  • Synthetic Pathways: The synthesis of this compound involves innovative synthetic strategies, often utilizing selective reactions that highlight the intricacies of organic chemistry.
  • Structure-Activity Relationships (SAR): Researchers are keenly interested in understanding how alterations in the compound's structure can affect its biological activity, paving the way for optimized drug design.

Research Highlights

In addition to its potential therapeutic applications, studies on 1-[2-hydroxy-4-[2-(1-piperidyl)ethoxy]phenyl]butan-1-one have provided insights into:

  • Mechanism of Action: Understanding how this compound interacts with specific receptors or enzymes can lead to breakthroughs in treatment methodologies.
  • Derivatives Development: Modifying the compound can lead to new variants that may have improved efficacy or reduced side effects.

As an emerging compound in the realm of pharmaceutical chemistry, 1-[2-hydroxy-4-[2-(1-piperidyl)ethoxy]phenyl]butan-1-one is more than just a chemical entity—it is a cornerstone for further scientific exploration and innovation.