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Morpholinium Chloride Derivative

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Identification
Molecular formula
C14H22ClNO4
CAS number
137590-44-6
IUPAC name
1-[2-hydroxy-4-(2-morpholin-4-ium-4-ylethoxy)phenyl]butan-1-one;chloride
State
State

At room temperature, this compound exists in a solid state, often found in a powdered or crystalline form. It should be stored in a cool, dry place to prevent clumping due to its hygroscopic nature.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
320.82g/mol
Molar mass
320.8180g/mol
Density
1.2000g/cm3
Appearence

This compound typically appears as a white to off-white crystalline solid. It is hygroscopic and may become clumpy upon exposure to moisture.

Comment on solubility

Solubility of 1-[2-hydroxy-4-(2-morpholin-4-ium-4-ylethoxy)phenyl]butan-1-one; chloride

The solubility of 1-[2-hydroxy-4-(2-morpholin-4-ium-4-ylethoxy)phenyl]butan-1-one; chloride can be influenced by several factors, particularly its ionic and polar characteristics due to the presence of the morpholinium group. This compound is expected to exhibit varying solubility depending on the solvent used. Here are some pertinent aspects:

  • Polar solvents: Compounds with polar functional groups, such as the hydroxy and morpholinium moieties, generally show increased solubility in polar solvents like water and ethanol. Thus, the chloride salt form is likely to be quite soluble in these environments.
  • Non-polar solvents: Conversely, in non-polar solvents (e.g., hexane or chloroform), the compound may exhibit significantly lower solubility due to the inability to effectively interact with the solvent molecules.
  • Temperature effects: Temperature adjustments can also affect solubility. As is commonly observed, increasing the temperature often enhances the solubility of solid compounds in liquids.
  • pH considerations: The solubility can additionally be affected by the pH of the solution. The ionization state of the morpholinium group may alter in response to the surrounding pH, influencing its solubility properties.

In summary: The solubility of this compound is multifaceted, primarily favoring polar solvents while being limited in non-polar environments. Understanding these nuances is essential for practical applications in pharmaceutical and chemical processes.

Interesting facts

Interesting Facts about 1-[2-Hydroxy-4-(2-morpholin-4-ium-4-ylethoxy)phenyl]butan-1-one; Chloride

This intriguing compound, commonly referred to as a quaternary ammonium salt, has gained attention in various fields due to its versatile chemical properties and biological activity. Below are some notable aspects:

  • Biological Activity: Compounds like this one are often investigated for their potential pharmacological effects, such as antimicrobial and antitumor properties. The presence of the morpholine moiety can enhance interactions with biological systems.
  • Solubility Versatility: The unique structure allows for better solubility in both aqueous and organic solvents, making it suitable for diverse applications in drug formulation and chemical synthesis.
  • Structure-Activity Relationship (SAR): The specific functional groups and their positions play a crucial role in determining the compound's reactivity and biological efficacy. Understanding the SAR can lead to the design of more effective derivatives.
  • Potential in Material Science: Beyond biological applications, this compound has potential uses in material science, particularly in creating multifunctional materials due to its ability to act as a ligand in coordination chemistry.

As scientists continue to explore the properties and applications of this compound, its relevance across disciplines only broadens. The study of quaternary ammonium compounds has not only enriched our understanding of chemical interactions but also opened new avenues for therapeutic development.

"The beauty of chemistry lies in its endless possibilities—every compound tells a story waiting to be discovered."
This quote encapsulates the journey of researching compounds like 1-[2-hydroxy-4-(2-morpholin-4-ium-4-ylethoxy)phenyl]butan-1-one; chloride and the excitement that comes with uncovering their multifaceted roles in science.

Synonyms
BUTYROPHENONE, 2'-HYDROXY-4'-(2-MORPHOLINOETHOXY)-, HYDROCHLORIDE
20800-12-8
2'-Hydroxy-4'-(2-(morpholino)ethoxy)butyrophenone hydrochloride
Butyrophenone, 6'-hydroxy-4'-(2-morpholinoethoxy)-, hydrochloride
RefChem:331371