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Piperazinyl chloroethanol

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Identification
Molecular formula
C15H22ClNO3
CAS number
223474-65-7
IUPAC name
1-[2-hydroxy-4-(2-piperidin-1-ium-1-ylethoxy)phenyl]ethanone;chloride
State
State

At room temperature, piperazinyl chloroethanol is generally in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
302.00
Boiling point (Kelvin)
575.15
General information
Molecular weight
329.83g/mol
Molar mass
329.8260g/mol
Density
1.2170g/cm3
Appearence

The compound typically appears as a white to off-white or pale-yellow crystalline powder. It is hygroscopic, meaning it can absorb moisture from the environment.

Comment on solubility

Solubility of 1-[2-hydroxy-4-(2-piperidin-1-ium-1-ylethoxy)phenyl]ethanone;chloride

The solubility of 1-[2-hydroxy-4-(2-piperidin-1-ium-1-ylethoxy)phenyl]ethanone;chloride is influenced by several factors due to its complex structure and ionic nature. Understanding its solubility characteristics is essential for practical applications. Here are some key points regarding its solubility:

  • Polarity: The presence of the piperidinium group and hydroxyl (-OH) functionality contributes to the polarity of the compound, enabling it to be soluble in polar solvents such as water.
  • Solvent Interaction: It is expected that the compound may exhibit improved solubility in aqueous solutions compared to non-polar organic solvents due to hydrogen bonding and ionic interactions.
  • pH Dependence: The solubility can also be influenced by the pH of the solution, with increased solubility in more acidic or basic conditions owing to possible protonation/deprotonation of the piperidine or hydroxyl groups.
  • Temperature Effects: Like many other chemical compounds, an increase in temperature may enhance the solubility of this chloride compound, as higher temperatures typically aid in breaking intermolecular interactions.
  • Concentration Dependence: As the concentration of the dissolved compound increases, one might observe a shift towards saturation, impacting further solubility.

In conclusion, while 1-[2-hydroxy-4-(2-piperidin-1-ium-1-ylethoxy)phenyl]ethanone;chloride shows favorable solubility in polar environments, factors such as polarity, temperature, and pH play crucial roles in determining its overall solubility profile. When handling this compound, adequate consideration of these factors will lead to more effective use in various chemical applications.

Interesting facts

Interesting Facts about 1-[2-hydroxy-4-(2-piperidin-1-ium-1-ylethoxy)phenyl]ethanone;chloride

This compound, often referred to in studies for its unique structural characteristics, is noteworthy for several reasons. It embodies a fascinating combination of functional groups that contribute to its reactivity and potential applications in various fields.

Chemical Structure and Functionality

At the core of this compound lies a phenolic derivative coupled with a piperidine moiety, which can significantly enhance its pharmacological activity. The compound features:

  • Hydroxy group - This contributes to the compound's ability to engage in hydrogen bonding, impacting its interaction with biological targets.
  • Piperidine ring - Known for its significance in medicinal chemistry, it plays a crucial role in influencing the compound's biological profile.
  • Ethanone functionality - This ketonic component may participate in various chemical reactions, enhancing the compound's versatility.

Potential Applications

The distinct molecular framework makes this compound a point of interest in research, particularly in:

  • Pharmaceutical Development - The characteristics of the piperidine and phenolic components suggest a role in drug design, particularly in targeting neurological pathways.
  • Biomedical Research - Investigations into its bioactivity could lead to discoveries related to its therapeutic effects.

Chemical Insights

One of the most intriguing aspects is the presence of the chloride ion in conjunction with the complex organic structure. This can affect:

  • Stability - The chloride can influence the compound's solubility in different media, which is essential for its biological studies.
  • Reactivity - The presence of halide ions can be leveraged in synthesis, leading to diverse derivatives and potential innovations.

As you delve deeper into the realm of this compound, you will come to appreciate not only its chemical attributes but also its potential to unlock new avenues in scientific research. In the words of renowned chemists, "The bond is just the beginning; the infinite possibilities lie in our understanding and manipulation of these bonds!"

Synonyms
Acetophenone, 6'-hydroxy-4'-(2-(piperidino)ethoxy)-, hydrochloride
21092-66-0
2'-Hydroxy-4'-(2-(piperidino)ethoxy)acetophenone hydrochloride
ACETOPHENONE, 2'-HYDROXY-4'-(2-(PIPERIDINO)ETHOXY)-, HYDROCHLORIDE
RefChem:316886