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Acetovanillone

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Identification
Molecular formula
C9H10O3
CAS number
498-02-2
IUPAC name
1-(2-hydroxy-4-methoxy-phenyl)ethanone
State
State

At room temperature, Acetovanillone exists as a solid. It is usually handled in its crystalline form.

Melting point (Celsius)
111.00
Melting point (Kelvin)
384.15
Boiling point (Celsius)
298.00
Boiling point (Kelvin)
571.15
General information
Molecular weight
166.17g/mol
Molar mass
166.1730g/mol
Density
1.1340g/cm3
Appearence

Acetovanillone appears as a white to light tan crystalline solid. It is known for its pleasant vanilla-like odor.

Comment on solubility

Solubility of 1-(2-hydroxy-4-methoxy-phenyl)ethanone

The solubility of 1-(2-hydroxy-4-methoxy-phenyl)ethanone (also known as a phenolic compound) can be influenced by several factors:

  • Polarity: The presence of both hydroxyl (-OH) and methoxy (-OCH3) groups in its structure imparts a degree of polarity, enhancing its solubility in polar solvents such as water.
  • Temperature: Generally, as temperature increases, solubility may also increase, particularly for solid compounds like this one.
  • Solvent Choice: This compound is likely to show good solubility in organic solvents like ethanol, methanol, and acetone, while having limited solubility in non-polar solvents.

In summary, it is essential to consider these characteristics when evaluating the solubility of 1-(2-hydroxy-4-methoxy-phenyl)ethanone in various media. It might be said that, due to its functional groups, it exhibits considerable solubility in polar environments while being less soluble in non-polar ones.

Interesting facts

Interesting Facts About 1-(2-hydroxy-4-methoxy-phenyl)ethanone

1-(2-hydroxy-4-methoxy-phenyl)ethanone, a compound belonging to the class of natural products, is widely recognized for its intriguing structural characteristics and potential applications. Here are some fascinating insights:

  • Natural Occurrence: This compound is a derivative of flavonoids and is often found in various plants, contributing to their therapeutic properties.
  • Biological Activity: It has gained attention for its antioxidant, anti-inflammatory, and potential anticancer activities, making it a subject of interest in pharmacological studies.
  • Chemical Structure: The presence of both -OH (hydroxyl) and -OCH3 (methoxy) groups on the aromatic ring significantly enhances the compound's reactivity and interaction with biological systems.
  • Synthetic Variants: Researchers have developed synthetic routes to create analogs of this compound, aiming to improve its efficacy and selectivity in medical applications.

As scientists continue to explore its potential, this compound exemplifies the intersection of natural chemistry and medicinal research. Its versatile structure not only allows for a variety of chemical reactions but also contributes to its rich biochemical properties. This compound serves as an excellent example of how nature inspires scientific exploration and innovation.

Synonyms
PAEONOL
552-41-0
1-(2-Hydroxy-4-methoxyphenyl)ethanone
Peonol
2-Hydroxy-4-methoxyacetophenone
Ethanone, 1-(2-hydroxy-4-methoxyphenyl)-
1-(2-hydroxy-4-methoxyphenyl)ethan-1-one
4-O-Methylresacetophenone
Resacetophenone-4-methyl ether
4'-Methoxy-2'-hydroxyacetophenone
Acetophenone, 2'-hydroxy-4'-methoxy-
NSC 401442
2-acetyl-5-methoxyphenol
Resacetophenone, 4-O-methyl ester
EINECS 209-012-2
UNII-3R834EPI82
BRN 1282794
AI3-10581
3R834EPI82
NSC-401442
RESACETOPHENONE 4-O-METHYL ETHER
4-08-00-01793 (Beilstein Handbook Reference)
1-(4-METHOXY-2-HYDROXYPHENYL)ETHANONE
2-HYDROXY-4-METHOXYPHENYL METHYL KETONE
2'-Hydroxy-4'-methoxyacetophenone
MFCD00008730
Paeonal
Paeonol (Peonol)
1-(2-hydroxy-4-methoxy-phenyl)ethanone
CHEMBL1079227
CHEBI:69581
1-(2-hydroxy-4-methoxy-phenyl)-ethanone
2-HYDROXY-4-METHOXYACETOPHENONE (4,4,4-D3)
Paeonol (Standard)
1-[2-hydroxy-4-(methyloxy)phenyl]ethanone
Spectrum2_001981
Spectrum3_001686
PAEONOL [WHO-DD]
2-Acetyl-5-methoxy-phenol
CBiol_000986
BSPBio_003212
MLS006011902
SPECTRUM1601021
SPBio_002161
SCHEMBL1449478
DTXSID1022059
HY-N0159R
KBio3_002432
4-methoxy 2-hydroxy acetophenone
HMS3656E07
HMS3884J13
2`-Hydroxy-4`-methoxyacetophenone
HY-N0159
BBL012127
BDBM50310718
CCG-39471
ICCB4_000282
MSK158477
NSC401442
s2339
STK078097
AKOS000119646
AC-7982
FH54161
SDCCGMLS-0066845.P001
1-(2-hydroxy-4-methoxyphenyl)-ethanone
NCGC00095977-01
NCGC00095977-02
NCGC00095977-03
2'-Hydroxy-4'-methoxyacetophenone, 99%
AS-15489
SMR000112386
SY013508
1-(2-Hydroxy-4-methoxyphenyl)ethanone #
1-(4-Methoxy-2-hydroxy-phenyl)-ethanone
1-(2-hydroxy-4-methoxyphenyl)ethane-1-one
H0789
NS00033267
SW219250-1
EN300-17920
1-(2-Hydroxy-4-methoxyphenyl)ethanone;Paeonol
Acetophenone, 2'-hydroxy-4'-methoxy-(7CI,8CI)
AL-968/20304013
SR-05000002397
Q7124105
SR-05000002397-1
BRD-K94239562-001-02-2
BRD-K94239562-001-03-0
BRD-K94239562-001-05-5
Z57101020
2 inverted exclamation mark -Hydroxy-4 inverted exclamation mark -methoxyacetophenone
InChI=1/C9H10O3/c1-6(10)8-4-3-7(12-2)5-9(8)11/h3-5,11H,1-2H