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Acetosyringone

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Identification
Molecular formula
C10H12O4
CAS number
2478-38-8
IUPAC name
1-(2-hydroxy-5-methoxy-4-methyl-phenyl)ethanone
State
State

At room temperature, acetosyringone is in a solid state. It is stable under normal conditions but should be stored in a dry and cool place to prevent degradation.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.00
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.00
General information
Molecular weight
196.21g/mol
Molar mass
196.2060g/mol
Density
1.1330g/cm3
Appearence

Acetosyringone is a white to off-white crystalline solid. This compound may appear as fine needles or in crystalline powder form. It has a mild aromatic odor.

Comment on solubility

Solubility of 1-(2-hydroxy-5-methoxy-4-methyl-phenyl)ethanone

The solubility of 1-(2-hydroxy-5-methoxy-4-methyl-phenyl)ethanone, a compound rich in functional groups, is influenced by various factors. As a ketone with additional hydroxyl and methoxy groups, it possesses unique properties that can affect its interaction with solvents.

Factors Influencing Solubility:

  • Polarity: The presence of the hydroxyl (-OH) and methoxy (-OCH3) groups increases the polarity of the molecule, which can enhance solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of the -OH group to form hydrogen bonds can lead to improved solubility in protic solvents.
  • Hydrophobic Interactions: The aromatic system and methyl groups may contribute to hydrophobic interactions, potentially limiting solubility in non-polar solvents.

Generally, you may find that this compound exhibits:

  • High solubility in polar organic solvents such as ethanol and methanol.
  • Moderate solubility in water due to its polar character, despite some hydrophobic portions.
  • Poor solubility in non-polar solvents like hexane or cyclohexane.

To summarize, "the solubility of 1-(2-hydroxy-5-methoxy-4-methyl-phenyl)ethanone varies significantly based on the solvent used, largely driven by the balance of polar and non-polar characteristics." Understanding these factors is crucial for its applications in various chemical contexts.

Interesting facts

Interesting Facts About 1-(2-Hydroxy-5-methoxy-4-methyl-phenyl)ethanone

1-(2-Hydroxy-5-methoxy-4-methyl-phenyl)ethanone, often abbreviated for convenience, is a fascinating compound that draws attention not only for its structure but also for its potential applications. Here are some intriguing aspects of this compound:

  • Biological Significance: This compound is related to various naturally occurring substances and exhibits properties that may be of interest in medicinal chemistry, particularly in research focusing on anti-inflammatory and antioxidant activities.
  • Structural Features: With hydroxyl and methoxy functional groups, this compound features a unique molecular architecture influencing its reactivity and interactions. The presence of a methyl group enhances its lipophilicity, which can affect its biological availability.
  • Chemical Reactivity: Derivatives of this compound can be synthesized for studying reactive intermediates. Researchers are keen to explore how modifications to the phenyl ring can alter the reactivity and potency of the compound, making it a valuable model in organic synthesis.
  • Natural Sources: This compound bears structural resemblance to flavonoids and other polyphenolic compounds often extracted from plants. Such compounds have traditionally been revered for their use in traditional medicine.
  • Applications in Research: The unique characteristics of 1-(2-hydroxy-5-methoxy-4-methyl-phenyl)ethanone make it a point of interest for studies involving drug discovery, particularly in screening for novel therapeutic agents.

As we continue to explore the realms of chemistry and biology, 1-(2-hydroxy-5-methoxy-4-methyl-phenyl)ethanone serves as a reminder of the intricate relationships between structure, function, and potential applications in medicinal chemistry. Its study not only broadens our understanding of chemical compounds but also inspires innovations in pharmaceuticals.

Synonyms
4223-84-1
1-(2-hydroxy-5-methoxy-4-methylphenyl)ethanone
2-HYDROXY-5-METHOXY-4-METHYLACETOPHENONE
1-(2-HYDROXY-5-METHOXY-4-METHYL-PHENYL)-ETHANONE
Ethanone,1-(2-hydroxy-5-methoxy-4-methylphenyl)-
SCHEMBL14566480
DTXSID90195055
AKOS006281158
from E:/powder/org3_fox/gsas/P21a.cif