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Acetophenone

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Identification
Molecular formula
C8H8O
CAS number
98-86-2
IUPAC name
1-(2-hydroxy-5-methyl-phenyl)ethanone
State
State

Acetophenone is typically a liquid at room temperature. However, it can solidify to form crystals depending on the ambient temperature.

Melting point (Celsius)
19.60
Melting point (Kelvin)
292.75
Boiling point (Celsius)
202.00
Boiling point (Kelvin)
475.15
General information
Molecular weight
120.15g/mol
Molar mass
120.1480g/mol
Density
1.0320g/cm3
Appearence

Acetophenone is a colorless, viscous liquid with a distinct sweet, floral aroma, resembling that of orange blossoms or jasmine. It can also present as crystalline when solidified. This compound is a common ingredient in fragrances and flavorings due to its pleasant smell.

Comment on solubility

Solubility of 1-(2-hydroxy-5-methyl-phenyl)ethanone

The solubility of 1-(2-hydroxy-5-methyl-phenyl)ethanone, also known as a type of ketone, can vary significantly based on its molecular interactions with solvents. Understanding its solubility characteristics is essential for its applications in various chemical processes. Here are some key points to consider:

  • Polarity: 1-(2-hydroxy-5-methyl-phenyl)ethanone contains both hydrophobic and hydrophilic regions. The presence of the hydroxyl group (-OH) increases its ability to interact with polar solvents.
  • Common Solvents: It is typically soluble in solvent types such as:
    • Alcohols (e.g., ethanol, methanol)
    • Ketones (e.g., acetone)
    • Aromatic hydrocarbons (e.g., toluene)
  • Insolubility: Conversely, this compound is generally insoluble or exhibits low solubility in non-polar solvents like hexane, due to its polar nature.
  • Temperature Effects: Temperature can also influence its solubility; generally, higher temperatures will improve solubility in certain solvents.

In summary, the solubility of 1-(2-hydroxy-5-methyl-phenyl)ethanone is influenced by its molecular structure, polarity, and the nature of the solvent. It serves as a reminder that "like dissolves like" in chemistry, making understanding solubility crucial for effective compound use.

Interesting facts

Interesting Facts About 1-(2-Hydroxy-5-methyl-phenyl)ethanone

1-(2-Hydroxy-5-methyl-phenyl)ethanone, commonly known in the scientific community as a compound with interesting applications and properties. Here are some notable facts:

  • Classification: This compound falls under the category of ketones, which are important functional groups in organic chemistry.
  • Natural Occurrence: It is often found in various natural sources, including plants and essential oils, contributing to its importance in the fragrance and flavor industries.
  • Biological Activity: Research indicates that this compound may exhibit significant biological properties, making it a candidate for pharmaceutical applications. For instance, it has been studied for its potential anti-inflammatory and antioxidant effects.
  • Synthesis: The synthesis of this compound can be achieved through methods involving the acetylation of the corresponding phenolic compound, demonstrating the versatility of organic reactions.
  • Industrial Use: It is utilized in the formulation of various products, including cosmetics and perfumes, due to its pleasant scent and compatibility with other aromatic compounds.

The compound serves as a prime example of how clever manipulation of molecular structures can lead to materials with diverse applications. As we delve further into organic chemistry, compounds like 1-(2-hydroxy-5-methyl-phenyl)ethanone remind us of the intricate relationship between structure and function in the chemistry of life.

Synonyms
1450-72-2
1-(2-Hydroxy-5-methylphenyl)ethanone
2'-Hydroxy-5'-methylacetophenone
2-Hydroxy-5-methylacetophenone
Ethanone, 1-(2-hydroxy-5-methylphenyl)-
o-Acetyl-p-cresol
2-ACETYL-4-METHYLPHENOL
1-(2-Hydroxy-5-Methylphenyl)Ethan-1-One
1-Hydroxy-2-acetyl-4-methylbenzene
Acetophenone, 2'-hydroxy-5'-methyl-
11661U1ZEN
EINECS 215-915-2
NSC-26458
NSC-63363
DTXSID9061702
FEMA NO. 4594
NSC 26458
NSC 63363
5'-METHYL-2'-HYDROXYACETOPHENONE
DTXCID0034720
Acetophenone, 2"-hydroxy-5"-methyl-
215-915-2
inchi=1/c9h10o2/c1-6-3-4-9(11)8(5-6)7(2)10/h3-5,11h,1-2h
MFCD00002380
1-(2-Hydroxy-5-methyl-phenyl)-ethanone
UNII-11661U1ZEN
NSC63363
2-Acetyl-p-cresol
NCIOpen2_000252
SCHEMBL471440
CHEMBL4444601
Methyl 6-hydroxy-m-tolyl ketone
CHEBI:179659
2'-hydroxy-5'-methyl-acetophenone
ALBB-019497
NSC26458
STK727255
AKOS000266093
FH33098
HY-W100681
SDCCGMLS-0065880.P001
1-(2-Hydroxy-5-methylphenyl)-Ethanone
2'-Hydroxy-5'-methylacetophenone, 98%
1-(2-Hydroxy-5-methylphenyl)ethanone #
BP-12459
PD171706
SY048474
DB-011374
1-(2-Hydroxy-5-methylphenyl)ethanone, 9CI
CS-0153323
H0790
NS00021663
EN300-18588
5D-073
1-(2-HYDROXY-5-METHYLPHENYL)-1-ETHANONE
Q27251292
Z85923114
2 inverted exclamation mark -Hydroxy-5 inverted exclamation mark -methylacetophenone