Skip to main content

Nitrofurazone

ADVERTISEMENT
Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
1-(2-hydroxyethyl)-1-[(5-nitro-2-furyl)methyleneamino]urea
State
State

At room temperature, nitrofurazone is typically a solid. It is stable under normal conditions of use and storage.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
334.00
Boiling point (Kelvin)
607.15
General information
Molecular weight
198.14g/mol
Molar mass
198.1390g/mol
Density
1.6553g/cm3
Appearence

Nitrofurazone typically appears as a yellow crystalline powder, which can vary slightly in hue depending on its purity and form. This distinctive coloration is due to its nitro and furan functional groups, which contribute to its characteristic appearance.

Comment on solubility

Solubility of 1-(2-hydroxyethyl)-1-[(5-nitro-2-furyl)methyleneamino]urea

The solubility of 1-(2-hydroxyethyl)-1-[(5-nitro-2-furyl)methyleneamino]urea can be influenced by various factors, including its molecular structure and the presence of functional groups. This compound features both hydrophilic and hydrophobic characteristics, suggesting differing solubility in various solvents.

In general, the solubility behavior can be summarized as follows:

  • Water: Due to the presence of a hydroxyl group (-OH), hydrophilic interactions enhance its solubility in polar solvents like water.
  • Organic Solvents: Given the furan ring and nitro group, the compound may exhibit moderate solubility in certain organic solvents such as ethanol or dimethyl sulfoxide (DMSO), where π-π interactions can occur.
  • Temperature Dependence: Higher temperatures may increase solubility, as increased molecular motion can facilitate interactions with solvent molecules.

In summary, while 1-(2-hydroxyethyl)-1-[(5-nitro-2-furyl)methyleneamino]urea shows a degree of solubility in water, it is essential to consider the specific solvent and environmental conditions to fully understand its solubility profile. As the expression goes, "solubility is key to understanding the behavior of chemical compounds in diverse environments."

Interesting facts

Interesting Facts about 1-(2-hydroxyethyl)-1-[(5-nitro-2-furyl)methyleneamino]urea

This compound, with its complex structure, is quite fascinating in the fields of medicinal chemistry and agricultural sciences. It features a unique combination of functional groups that contribute to its biological activity.

1. Structural Diversity

  • The presence of the nitro group in the furan ring enhances its reactivity and potential biological activity.
  • With a hydroxyethyl substituent, this compound exhibits characteristics that may aid in enhancing solubility and bioavailability.

2. Biological Applications

This compound's chemical structure positions it as a potential candidate for various therapeutic uses:

  • It may exhibit antimicrobial and antitumor properties, making it a subject of interest in cancer research.
  • Its structural components can contribute to mechanisms seen in antiparasitic drugs.

3. Synthesis and Reactions

The synthesis of this compound involves well-established reactions common in organic chemistry, such as:

  • Condensation reactions that result in the linking of the urea moiety to the furan derivative.
  • The manipulation of the hydroxyethyl group which may influence the overall reactivity of the compound.

4. Research Potential

Ongoing research is crucial in understanding the full potential of 1-(2-hydroxyethyl)-1-[(5-nitro-2-furyl)methyleneamino]urea. Scientists are looking into:

  • How its unique structure affects cell signaling pathways.
  • The exploration of its effects on regulatory mechanisms in cells.
  • Possibilities for creating derivatives that could enhance efficacy or reduce side effects.

Quote

As many researchers state, "The journey of a compound is only as fascinating as the transformations it undergoes." This statement embodies the exploration and potential of this intriguing molecule.

In conclusion, the multifaceted nature of 1-(2-hydroxyethyl)-1-[(5-nitro-2-furyl)methyleneamino]urea invites further investigation and application in various scientific domains.

Synonyms
DTXSID701015578
SCHEMBL11091830
Hydrazinecarboxamide,1-(2-hydroxyethyl)-2-[(5-nitro-2-furanyl)methylene]-
NS00043205