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Mitoxantrone

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Identification
Molecular formula
C22H28N4O6
CAS number
65271-80-9
IUPAC name
1-(2-hydroxyethylamino)-4-(methylamino)anthracene-9,10-dione
State
State

At room temperature, Mitoxantrone is in a solid state, commonly available in powdered form for use in pharmaceutical applications.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.00
Boiling point (Celsius)
550.00
Boiling point (Kelvin)
823.00
General information
Molecular weight
517.43g/mol
Molar mass
517.4290g/mol
Density
1.3315g/cm3
Appearence

Mitoxantrone appears as a dark blue-green crystalline powder. It is known for its intensely dark color which is typical for anthraquinone derivatives.

Comment on solubility

Solubility of 1-(2-hydroxyethylamino)-4-(methylamino)anthracene-9,10-dione

The solubility of 1-(2-hydroxyethylamino)-4-(methylamino)anthracene-9,10-dione can be influenced by various factors. This compound, often characterized by its complex molecular structure, demonstrates certain properties that affect its solubility:

  • Polar and Non-Polar Interactions: The presence of both hydroxyethyl and methylamino groups introduces polar characteristics, which can enhance solubility in polar solvents such as water.
  • Solvent Compatibility: Since anthracene derivatives tend to be less soluble in non-polar solvents, this compound may exhibit better solubility in mixtures that include polar organic solvents (e.g., ethanol, methanol).
  • Temperature effects: Like many organic compounds, increasing the temperature may improve solubility, allowing more of the compound to dissolve in a given volume of solvent.
  • pH Sensitivity: Changes in pH can influence the ionization state of the amino groups, potentially affecting the solubility in aqueous solutions.

Overall, understanding the solubility of this compound requires considering its unique chemical structure. As with many organic compounds, solubility can be complex and may shift under different environmental conditions.

Interesting facts

Interesting Facts About 1-(2-hydroxyethylamino)-4-(methylamino)anthracene-9,10-dione

1-(2-hydroxyethylamino)-4-(methylamino)anthracene-9,10-dione, often referred to simply as a derivative of anthracene, is a fascinating compound that holds a significant place in organic chemistry and material science.

Key Characteristics:

  • Photochemical Properties: This compound is known for its fluorescence properties, making it useful in applications such as dyes and sensors.
  • Synthesis: The synthesis of this compound involves intricate organic reactions, offering students an excellent example of functional group manipulation and complex molecule construction.
  • Biological Significance: Compounds of this nature have been studied for their potential biological applications, including anticancer properties, which makes them a subject of interest in medicinal chemistry.

Moreover, the presence of both hydroxy and amino groups in its structure enhances its reactivity and versatility in forming various derivatives. This compound also serves as a crucial model for understanding the behavior of more complex organic molecules.

Fun Fact:

Did you know that anthracene derivatives are often used in OLED (organic light-emitting diode) technology? Their ability to emit light upon excitation makes them integral in this rapidly advancing area of electronics.

In summary, 1-(2-hydroxyethylamino)-4-(methylamino)anthracene-9,10-dione is not only a key player in the lab but also an important compound within the broader context of material science and pharmacology.

Synonyms
Disperse blue 3
C.I. Disperse Blue 3
2475-46-9
1-Ma-4oeaa
Disperse Blue K
Setacyl Blue BN
Setacyl Blue FG
Setacyl Blue RF
Amacel Blue BNN
Artisil Blue BSG
Artisil Blue BSQ
Cibacet Blue BNG
Eastman Blue BNN
Eastman Blue GBN
Nacelan Blue KLT
Celliton Blue FFR
Celutate Blue BLT
Celutate Blue RNH
Cibacet Blue F3R
Perliton Blue FFR
Microsetile Blue FF
Serinyl Hosiery Blue
Microsetile Blue FFR
Nyloquinone Pure Blue
Cilla Fast Blue FFR
Fenacet Fast Blue FF
Kayalon Fast Blue FN
Setacyl Brilliant Blue
Fenacet Fast Blue FFN
Celliton Fast Blue FFR
Lurafix Blue FFR
Amacel Brilliant Blue B
Duranol Printing Blue B
Nyloquinone Pure Blue R
Serinyl Hosiery Blue BG
Altocyl Brilliant Blue B
Calcosyn Sapphire Blue R
Duranol Brilliant Blue B
Interchem Acetate Blue B
Miketon Brilliant Blue B
Celliton Fast Blue FBBN
Celliton Fast Blue FFRN
Celliton Fast Blue FFRS
Akasperse Blue GLF
Celanthrene Brilliant Blue
Modr ostacetova p3r
Celutate Brilliant Blue B
Duranol Brilliant Blue BN
Serisol Brilliant Blue BG
Serisol Brilliant Blue BP
Serisol Brilliant Blue FF
Setacyl Brilliant Blue BG
Acetate Brilliant Blue 4B
Lurafix Blue 660
Supracet Brilliant Blue BG
Calcosyn Sapphire Blue 2GS
Interchem Acetate Blue NBN
Interchem Acetate Blue RBN
Interchem Acetate Blue WNBN
Toray blue
Transetile Blue P-FER
Transetile Blue P-FFR
Celanthrene Brilliant Blue FFS
Acetoquinone Light Pure Blue R
Cibacete Brilliant Blue BG new
Modr Disperzni 3
C.I. 61505
Atlantic Disperse Blue BNA
Diacelliton Fast Brilliant Blue B
Modr Disperzni 3 [Czech]
1-Methylamino-4-ethanolaminoanthraquinone
1-MA-4OEAA [Russian]
Diacelliton Fast Brilliant Blue BF
C. I. Disperse Blue 41
C. I. Disperse Blue 66
Modr Ostacetova P3R [Czech]
CCRIS 3734
1-[(2-hydroxyethyl)amino]-4-(methylamino)-9,10-anthracenedione
HSDB 5533
Serisol Brilliant Blue BGN 300
1-Methylamino-4-oxyethylaminoanthraquinone
EINECS 219-604-2
NSC 64753
BRN 2060684
Cibacet Blue F 3R
CI 61505
EINECS 289-276-3
NSC-64753
8X7KL92596
CI DISPERSE BLUE 3
1-Methylamino-4-oxyethylaminoanthraquinone [Russian]
9,10-Anthracenedione, 1-((2-hydroxyethyl)amino)-4-(methylamino)-
1-(Methylamino)-4-(2-hydroxyethylamino)anthraquinone
C.I. DISPERSE BLUE 3 [HSDB]
1-(beta-Hydroxyethylamino)-4-(methylamino)anthraquinone
9,10-Anthracenedione, 1-[(2-hydroxyethyl)amino]-4-(methylamino)-
Anthraquinone, 1-((2-hydroxyethyl)amino)-4-(methylamino)-
Anthraquinone, 1-[(2-hydroxyethyl)amino]-4-(methylamino)-
1-((2-Hydroxyethyl)amino)-4-(methylamino)-9,10-anthracenedione
Transetile Blue PFER
Transetile Blue PFFR
1MA4OEAA
CELANTHREN BRILLIANT BLUE
DISPERSE BLUE 3 [INCI]
DTXSID9041730
1Methylamino4oxyethylaminoanthraquinone
9,10Anthracenedione, 1((2hydroxyethyl)amino)4(methylamino)
9,10-Anthracenedione, 1-(2-hydroxyethyl)amino-4-(methylamino)-
Anthraquinone, 1-((2-hydroxyethyl)amino)-4-(methylamino)-(8CI)
86722-66-9
1-(2-Hydroxyethylamino)-4-(methylamino)anthraquinone
1-(2-hydroxyethylamino)-4-(methylamino)anthracene-9,10-dione
1-[(2-HYDROXYETHYL)AMINO]-4-(METHYLAMINO)ANTHRAQUINONE
MFCD00001199
1-((2-Hydroxyethyl)amino)-4-(methylamino)anthraquinone
Disperse Blue 3 (20% dye content)
UNII-8X7KL92596
Dispersive blue K
Mireton Brilliant Blue B
Disperse Blue 3, tech.
C.I. Disperse Blue 41
NCIOpen2_003132
SCHEMBL23404
BIDD:GT0458
Cibacet Brilliant Blue BG new
DTXSID301015819
NSC64753
STK000027
Disperse Blue 3, Dye content 20 %
AKOS015903427
WLN: L C666 BV IVJ DM2Q GM1
1-(Methylamino)-4-ethanolaminoanthraquinone
DB-258704
NS00009216
9, 1-[(2-hydroxyethyl)amino]-4-(methylamino)-
4-[(Hydroxyethyl)amino]-1-(methylamino)anthraquinone
Q27271150
Disperse Blue 3 100 microg/mL in Acetonitrile:Methanol
1-(.beta.-Hydroxyethylamino)-4-(methylamino)anthraquinone
1-(Methylamino)-4-(.beta.-hydroxyethylamino)anthraquinone
1-[(2-hydroxyethyl)amino]-4-(methylamino)anthracene-9,10-dione
9,10-Anthracenedione, 1,4-diamino-N-methyl-N'-(2-hydroxyethyl)-
1-(2-Hydroxyethylamino)-4-(methylamino)anthraquinone; Anthraquinone, 1-[(2-hydroxyethyl)amino]-4-(methylamino)- (6CI,7CI); 1-[(2-Hydroxyethyl)amino]-4-(methylamino)-9,10-anthracenedione; 1-(2-Hydroxyethylamino)-4-(methylamino)anthraquinone; NSC 64753; Serisol Brilliant Blue BGN 300