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2'-Hydroxyacetophenone

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Identification
Molecular formula
C8H8O2
CAS number
118-93-4
IUPAC name
1-(2-hydroxyphenyl)ethanone
State
State

At room temperature, 2'-Hydroxyacetophenone is typically in a solid state as a crystalline powder. It is stable under normal conditions but must be stored properly to prevent sublimation.

Melting point (Celsius)
86.00
Melting point (Kelvin)
359.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
136.15g/mol
Molar mass
136.1480g/mol
Density
1.1660g/cm3
Appearence

2'-Hydroxyacetophenone appears as colorless to light yellow crystals or powder. It has a pleasant odor which can be detected at room temperature.

Comment on solubility

Solubility of 1-(2-hydroxyphenyl)ethanone

1-(2-hydroxyphenyl)ethanone, also known as 2-Hydroxyacetophenone, exhibits notable solubility characteristics that are intriguing for various applications. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is generally soluble in organic solvents such as ethanol and acetone, making it useful in organic synthesis and reaction processes.
  • Aqueous Solubility: While it has limited solubility in water, the presence of the hydroxyl group can slightly enhance its solubility in polar solvents compared to non-polar substances.
  • Temperature Dependence: Like many organic compounds, its solubility can be influenced by temperature; increasing temperature often leads to higher solubility in its preferred organic solvents.

In summary, the solubility of 1-(2-hydroxyphenyl)ethanone in various solvents showcases its versatility in applications, particularly in chemical synthesis. As with many compounds, understanding the solubility behavior is crucial for optimizing its use in practical scenarios.

Interesting facts

Interesting Facts About 1-(2-Hydroxyphenyl)ethanone

1-(2-Hydroxyphenyl)ethanone, also known as 2-Hydroxyacetophenone, is a fascinating compound that finds its significance in various fields, particularly in organic chemistry and materials science. Here are some intriguing insights:

  • Key Role in Organic Synthesis: This compound serves as an intermediate in the synthesis of various organic compounds, highlighting its versatility in chemical reactions.
  • Pharmaceutical Applications: Compounds similar to 1-(2-hydroxyphenyl)ethanone exhibit pharmacological activities, making it relevant in drug discovery and development.
  • Functional Group Influence: The presence of the hydroxyl group (-OH) adjacent to the ketone group influences the compound's reactivity, making it a valuable target for various chemical reactions.
  • UV Absorption Properties: It has unique UV absorption characteristics, allowing its use in photochemical studies and applications in UV-filtering agents.
  • Potential in Dye Synthesis: 1-(2-Hydroxyphenyl)ethanone can be involved in the synthesis of dyes and pigments, contributing to the field of material sciences.

In the words of chemists, "Understanding the properties and reactions of compounds like 2-Hydroxyacetophenone not only enriches our knowledge but also paves the way for innovative applications across numerous disciplines." Such compounds demonstrate the intricate dance of chemistry, where structure and function intertwine seamlessly.

This compound stands out because of its rich chemical behavior and the myriad of potential applications it holds, making it a staple subject of study for aspiring chemists and researchers alike.

Synonyms
2'-Hydroxyacetophenone
118-93-4
1-(2-Hydroxyphenyl)ethanone
2-Acetylphenol
O-HYDROXYACETOPHENONE
o-Acetylphenol
o-Hydroxyphenyl methyl ketone
104809-67-8
1-(2-Hydroxyphenyl)Ethan-1-One
2-Hydroxyphenyl methyl ketone
Acetophenone, 2'-hydroxy-
Ethanone, 1-(2-hydroxyphenyl)-
Methyl 2-hydroxyphenyl ketone
Acetophenone, o-hydroxy-
USAF KE-20
2/'-Hydroxyacetophenone
FEMA No. 3548
125507-95-1
NSC 16933
2-Hydroxyacetylbenzene
MFCD00002219
1-(2-hydroxyphenyl)-ethanone
CHEMBL3187012
DTXSID7040285
2-Acetophenol
NSC-16933
3E533Z76W0
2,4-Cyclohexadien-1-one, 6-(1-hydroxyethylidene)- (9CI)
WLN: QR BV1
Ethanone, 1-(hydroxyphenyl)-
1189865-36-8
FEMA 3548
Paracetamol Impurity I
2'-hydroxy-acetophenone
EINECS 204-288-0
BRN 0386123
o-acetyl phenol
AI3-12134
UNII-3E533Z76W0
1-(2-Hydroxyphenyl)ethanone; Paracetamol Imp. I (EP); 2-Hydroxyacetophenone; Paracetamol Impurity I
2,4-Cyclohexadien-1-one, 6-(1-hydroxyethylidene)-
orthohydroxyacetophenone
2`-Hydroxyacetophenone
2\'-Hydroxyacetophenone
Ethanone,1-(2-hydroxyphenyl)-, labeled with carbon-14 (9CI)
1-(hydroxyphenyl)ethanone
1-(2-Hydroxyphenyl)etanone
SCHEMBL40865
2-Acetophenol;2-Acetylphenol
4-08-00-00320 (Beilstein Handbook Reference)
ACETOPHENONE,2-HYDROXY
1-(2-hydroxy-phenyl)ethanone
1-(2-hydroxy phenyl)-ethanone
1-(2-hydroxy-phenyl)-ethanone
2'-Hydroxyacetophenone - 95%
DTXCID5020285
HY-Y1426R
NSC9263
2'-Hydroxyacetophenone, >=98%
CHEBI:145716
2'-Hydroxyacetophenone (Standard)
1-(2-Hydroxyphenyl)ethanone, 9CI
Acetophenone, 2'-hydroxy- (8CI)
HY-Y1426
NSC-9263
NSC16933
NSC44452
PXB86536
STR00372
Tox21_301119
2-HYDROXYACETOPHENONE [FHFI]
BBL012126
BDBM50140214
NSC-44452
s9375
STL163508
2`-Hydroxyacetophenone 2-Acetylphenol
AKOS000118832
AC-5622
CCG-266129
CS-W020051
FH64535
PS-3396
NCGC00248294-01
NCGC00257527-01
BP-13220
CAS-118-93-4
FH171307
2'-Hydroxyacetophenone, analytical standard
DB-269423
H0192
NS00020731
PARACETAMOL IMPURITY I [EP IMPURITY]
EN300-18385
2'-Hydroxyacetophenone, ReagentPlus(R), 99%
D70588
2'-Hydroxyacetophenone (Acetaminophen Impurity I)
doi:10.14272/JECYUBVRTQDVAT-UHFFFAOYSA-N.1
Q27257104
Z57101014
2'-Hydroxyacetophenone, Vetec(TM) reagent grade, 98%
F1908-0162
InChI=1/C8H8O2/c1-6(9)7-4-2-3-5-8(7)10/h2-5,10H,1H