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1-Aminopropan-2-ol

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Identification
Molecular formula
C6H15NO2
CAS number
78-96-6
IUPAC name
1-(2-hydroxypropylamino)propan-2-ol
State
State

At room temperature, 1-Aminopropan-2-ol is typically in a liquid state. It has a slightly viscous nature, which is characteristic of this type of organic compound.

Melting point (Celsius)
-2.00
Melting point (Kelvin)
271.00
Boiling point (Celsius)
181.00
Boiling point (Kelvin)
454.00
General information
Molecular weight
89.14g/mol
Molar mass
89.1410g/mol
Density
0.9300g/cm3
Appearence

1-Aminopropan-2-ol is a colorless to pale yellow liquid with a slightly viscous texture. It may be presented as a clear liquid without any impurities visible to the naked eye.

Comment on solubility

Solubility of 1-(2-hydroxypropylamino)propan-2-ol

The compound 1-(2-hydroxypropylamino)propan-2-ol exhibits noteworthy solubility characteristics that are crucial for its applications. This compound showcases a strong ability to dissolve in polar solvents, particularly in:

  • Water: Being a hydroxyl-containing amine, it is highly soluble in water due to hydrogen bonding interactions.
  • Alcohols: The presence of hydroxyl groups enhances its solubility in common alcohols, facilitating various chemical reactions and formulations.

Its solubility can be primarily attributed to the following factors:

  1. Hydrogen Bonding: The hydroxyl groups provide sites for hydrogen bonding, leading to strong interactions with solvent molecules.
  2. Polarity: The polar nature of the amine and hydroxyl functionalities increases the overall polarity, making it compatible with polar solvents.

However, it is important to note that while 1-(2-hydroxypropylamino)propan-2-ol is readily soluble in polar solvents, its solubility in nonpolar solvents may be significantly diminished. As a result, one can observe the tendency of such compounds to exhibit:

  • A preference for aqueous phases in biological systems, which is essential for its biological activity.
  • Effective solubilization properties that enhance its use in various chemical formulations.

In conclusion, the solubility profile of 1-(2-hydroxypropylamino)propan-2-ol underlines its versatility and functional significance in both laboratory and industrial settings.

Interesting facts

Interesting Facts about 1-(2-Hydroxypropylamino)propan-2-ol

1-(2-Hydroxypropylamino)propan-2-ol, often abbreviated for convenience, is a fascinating compound with a range of applications, particularly in the field of pharmaceuticals and biochemistry. Here are some noteworthy points about this compound:

  • Functionality: As an amino alcohol, this compound possesses both hydroxyl (-OH) and amino (-NH2) functional groups, making it versatile for various chemical reactions and applications.
  • Biological Significance: Compounds like 1-(2-hydroxypropylamino)propan-2-ol can act as intermediates in the synthesis of important biomolecules, particularly those used for drug development.
  • Surfactant Properties: Due to its structure, this compound may exhibit surfactant properties, which can be useful in formulations where emulsification or solubilization is necessary.
  • Chiral Center: With its specific arrangement, this compound can exist in different enantiomeric forms, leading to variations in biological activity. This makes it an interesting compound for chiral synthesis and study.
  • Applications in Medicine: There is potential for this compound to be used in drug formulations, particularly in therapies that require targeting specific receptors or pathways in biological systems.

As you can see, even though 1-(2-hydroxypropylamino)propan-2-ol may not be as widely recognized as some other compounds, it holds significant potential for further study and application in both chemistry and pharmacology. The exploration of its properties and contributions to various fields can open new avenues in research and innovation!

Synonyms
DIISOPROPANOLAMINE
110-97-4
Bis(2-hydroxypropyl)amine
1,1'-Iminodipropan-2-ol
Bis(2-propanol)amine
1,1'-Iminodi-2-propanol
2-Propanol, 1,1'-iminobis-
Di-2-propanolamine
di-isopropanolamine
DIPA (alcohol)
1-[(2-hydroxypropyl)amino]propan-2-ol
Dipropyl-2,2'-dihydroxy-amine
N,N-Bis(2-hydroxypropyl)amine
1-(2-hydroxypropylamino)propan-2-ol
1,1'-Iminobis-2-propanol
2-Propanol, 1,1'-iminodi-
NSC 4963
2-Propanol,1,1'-iminobis-
CCRIS 6234
HSDB 338
Diisopropanolamine [NF]
diisopropanolamin
DIPA alcohol
NSC-4963
EINECS 203-820-9
1,1'-Iminobis[2-propanol]
BRN 0605363
0W44HYL8T5
DTXSID8020179
di(2-hydroxypropyl)amine
DTXCID20179
DIISOPROPANOLAMINE [II]
DIISOPROPANOLAMINE [MI]
1,1'-azanediylbis propan-2-ol
DIISOPROPANOLAMINE [HSDB]
1,1'-azanediyldi(propan-2-ol)
CHEBI:143266
DIISOPROPANOLAMINE [VANDF]
DIISOPROPANOLAMINE [MART.]
EC 203-820-9
3-04-00-00761 (Beilstein Handbook Reference)
1,1'-IMINOBIS(2-PROPANOL)
Diisopropanolamine (NF)
1335-54-2
DIISOPROPANOLAMINE (II)
DIISOPROPANOLAMINE (MART.)
1,1'-Azanediylbis(propan-2-ol)
1-((2-hydroxypropyl)amino)propan-2-ol
203-820-9
CAS-110-97-4
DI-ISOPROPANOL AMINE
UNII-0W44HYL8T5
Di2propanolamine
diiso-propanolamine
diisopropanol amine
1,1'-IMINODI-2-PROPANOL(Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253)
1,1'-IMINODI-2-PROPANOL[Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253]
BIS(2-HYDROXYPROPYL)AMINE(Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253)
BIS(2-HYDROXYPROPYL)AMINE[Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253]
BIS(2-PROPANOL)AMINE(Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253)
BIS(2-PROPANOL)AMINE[Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 1253]
Bis(2propanol)amine
MFCD00004531
1,1'Iminodi2propanol
1,1'Iminodipropan2ol
1,1'Iminobis2propanol
Bis(2-propanol) amine
Bis(2hydroxypropyl)amine
2-Propanol,1'-iminodi-
2Propanol, 1,1'iminodi
1,1'-Imino-2-propanol
2-Propanol,1'-iminobis-
2Propanol, 1,1'iminobis
Dipropyl2,2'dihydroxyamine
bis-(2-hydroxypropyl)amine
N,NBis(2hydroxypropyl)amine
bis-(2-hydroxypropyl)-amine
SCHEMBL22774
Di(2-hydroxy-n-propyl) amine
1,1'-Imino-di(2-propanol)
CHEMBL2106303
DIISOPROPANOLAMINE [INCI]
NSC4963
WLN: QY1 & 1M1YQ1
2,2'-DIHYDROXYDIPROPYLAMINE
Tox21_201602
Tox21_302859
BBL013266
STK503623
AKOS005457854
DIPA low freeze grade 85 (Salt/Mix)
DIPA low freeze grade 90 (Salt/Mix)
NCGC00249081-01
NCGC00256476-01
NCGC00259151-01
VS-03726
Diisopropanolamine(DL- and meso- mixture)
Bis(2-hydroxypropyl)amine, >=98.0% (T)
D0924
NS00001427
EN300-722418
Q777543
F0001-0230
9AFD2C98-2177-4499-8EB2-1C8EA079F21D