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Methamphetamine

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Identification
Molecular formula
C10H15NO
CAS number
537-46-2
IUPAC name
1-(2-methoxyphenyl)-N-methyl-propan-2-amine
State
State

State at Room Temperature: Methamphetamine is usually found in a crystalline solid or powder at room temperature. The compound is stable and does not evaporate easily, which contributes to its persistence in the environment.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
0.9708g/cm3
Appearence

Methamphetamine is typically found as a white crystalline powder or small crystals similar in appearance to coarse salt or sugar. When in its crystalline form, it is commonly referred to as 'crystal meth' and has a translucent to white color with a glass-like appearance.

Comment on solubility

Solubility of 1-(2-methoxyphenyl)-N-methyl-propan-2-amine (C10H15NO)

Understanding the solubility of 1-(2-methoxyphenyl)-N-methyl-propan-2-amine is essential for its applications in various chemical processes. This compound, characterized by its unique structure, demonstrates a range of solubility traits:

  • Solvent Compatibility: Generally, this compound is more soluble in organic solvents than in water, which is typical for many amines.
  • Polarity Considerations: The presence of the methoxy group enhances the overall polarity of the molecule, potentially increasing its solubility in polar organic solvents.
  • Temperature Influence: Like many organic compounds, solubility may increase with temperature, allowing for better dissolution in solvents when heated.

It is important to note that solubility can vary significantly based on the specific solvent used and the conditions under which the solubility is measured. For practical applications, experimentation with different solvents such as ethanol, acetone, or dichloromethane is recommended to find the optimal conditions for dissolution.

In summary, while 1-(2-methoxyphenyl)-N-methyl-propan-2-amine may not exhibit high solubility in water, its behavior in organic solvents can still provide valuable insights for its utilization in synthetic and analytical chemistry.

Interesting facts

Interesting Facts about 1-(2-methoxyphenyl)-N-methyl-propan-2-amine

1-(2-methoxyphenyl)-N-methyl-propan-2-amine, commonly referred to in the realm of organic chemistry, is a fascinating compound with several intriguing aspects worth exploring.

Chemical Structure and Properties

This compound features a structure that includes a methoxy group and a propan-2-amine moiety, which can significantly influence its biological activity. The presence of the methoxy group can enhance lipophilicity, thereby improving its ability to penetrate biological membranes.

Biological Relevance

  • Pharmacological Potential: Compounds like this one are often investigated for their psychoactive properties, similar to other derivatives of amphetamines, and contribute knowledge to the study of central nervous system stimulants.
  • Research Applications: Researchers may study it for potential use in treating conditions such as ADHD or depression, highlighting its significance in medicinal chemistry.
  • Analytical Interest: This compound often finds its way into forensic science due to its structural similarities with other illicit substances.

Historical Context

The exploration of compounds like 1-(2-methoxyphenyl)-N-methyl-propan-2-amine is rooted in a long history of synthetic organic chemistry. It illustrates how small modifications in a molecule can lead to markedly different pharmacological profiles, which is a fundamental principle in drug development.

Potential Risks

While there are exciting avenues for discovery, it's crucial to note that compounds with similar structures can pose risks. Their potential for misuse and the challenge of regulation are ongoing concerns for scientists and policymakers alike.

As we delve deeper into the chemistry of compounds like 1-(2-methoxyphenyl)-N-methyl-propan-2-amine, we uncover the balance between pharmacology and safety—an essential endeavor in the advancement of medicinal chemistry!

Synonyms
METHOXYPHENAMINE
Orthoxine
93-30-1
Methoxiphenadrin
Methoxyphenamin
Ortodrinex
Euspirol
2-Methoxymethamphetamine
Proasma
Methoxifenaminio
Methoxyphenaminum
Methoxiphenadrinum
metoxifenamina
Metossifenamina
Metoxifenaminio
Ortoxine
Methoxyphenadrine
Metossifenamina [DCIT]
Oxalacetic acid orthoxine
Methoxyphenamine [INN:BAN]
Methoxyphenaminum [INN-Latin]
Metoxifenaminio [INN-Spanish]
1-(2-methoxyphenyl)-N-methylpropan-2-amine
Phenethylamine, 2-methoxy-N,alpha-dimethyl-
EINECS 202-237-7
J3Z5SRI26Z
2-Methoxy-N,alpha-dimethylphenethylamin
o-Methoxy-N,alpha-dimethylphenethylamine
Benzeneethanamine, 2-methoxy-N,.alpha.-dimethyl-
DTXSID0023292
Methamphetamine, 2-methoxy
2-methoxy-N,alpha-dimethylphenethylamine
METHOXYPHENAMINE [MI]
2-Methoxy-N-methylamphetamine
METHOXYPHENAMINE [INN]
DTXCID203292
Benzeneethanamine, 2-methoxy-N,alpha-dimethyl-
METHOXYPHENAMINE [WHO-DD]
CHEBI:134817
[1-(2-methoxyphenyl)propan-2-yl](methyl)amine
NCGC00159469-02
1-(o-Methoxyphenyl)-2-methylaminopropane
Phenethylamine, o-methoxy-N,.alpha.-dimethyl-
O-METHOXY-N,.ALPHA.-DIMETHYLPHENETHYLAMINE
Methoxyphenaminum (INN-Latin)
Metoxifenaminio (INN-Spanish)
mimexina
CAS-93-30-1
2-METHOXYPHENAMINE HCL
(1-(2-methoxyphenyl)propan-2-yl)(methyl)amine
UNII-J3Z5SRI26Z
OMMA
1-(2-methoxyphenyl)-2-methylaminopropane
SCHEMBL218289
CHEMBL2010507
R03CB02
Tox21_113045
BDBM50595336
AKOS009939590
Tox21_113045_1
DB13624
NCGC00159469-03
NCGC00159469-04
AC-16015
beta-(o-Methoxyphenyl)isopropylmethylamine
NCI60_019552
O-Methoxy-N,alpha-dimethyl-Phenethylamine
2-Methoxy-N,.alpha.-dimethylphenethylamine
2-Methoxy-N,alpha-dimethylbenzeneethanamine
.beta.-(o-Methoxyphenyl)isopropylmethylamine
1-(2-Methoxyphenyl)-N-methyl-2-propanamine
2-Methoxy-N,alpha-dimethyl-Benzeneethanamine
NS00017734
2-Methoxy-N,.alpha.-dimethylbenzeneethanamine
EN300-92107
alpha-(2-Methoxyphenyl)-beta-methylaminopropane
N10866
N-methyl-1-[2-(methyloxy)phenyl]propan-2-amine
SR-01000944496
.alpha.-(2-Methoxyphenyl)-.beta.-methylaminopropane
Q6823901
SR-01000944496-1
BRD-A21474126-001-01-6
202-237-7