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1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone

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Identification
Molecular formula
C13H13NO
CAS number
80841-78-7
IUPAC name
1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone
State
State

Solid at room temperature: This compound exists as a solid under standard room temperature conditions (25°C and 1 atm).

Melting point (Celsius)
59.00
Melting point (Kelvin)
332.15
Boiling point (Celsius)
387.00
Boiling point (Kelvin)
660.15
General information
Molecular weight
197.26g/mol
Molar mass
197.2550g/mol
Density
1.0670g/cm3
Appearence

1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone appears as a crystalline solid. It may exhibit a range of colors depending on purity and specific crystal formation, often appearing white or off-white. This compound, like many aromatic ketones, can be sensitive to light and air.

Comment on solubility

Solubility of 1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone

The solubility of 1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone (C13H13NO) is influenced by its molecular structure, especially the presence of both hydrophobic and hydrophilic regions. Generally, the solubility can be characterized as follows:

  • Solvent Compatibility: The compound is likely to be soluble in organic solvents such as ethanol, methanol, and dichloromethane, owing to its non-polar aromatic components.
  • Polarity Considerations: With a lone nitrogen atom and the carbonyl group, the compound may exhibit some degree of polarity, which can enhance its solubility in polar solvents to a limited extent.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature. Higher temperatures can facilitate the dissolution process.
  • Poor Water Solubility: It is likely that 1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone exhibits low solubility in water due to its hydrophobic characteristics, which often leads to segregation in aqueous environments.

In summary, the solubility of 1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone can be described as:

  1. Soluble in organic solvents
  2. Poorly soluble in water
  3. Temperature dependent

Understanding these solubility characteristics is essential for applications in both research and industrial contexts.

Interesting facts

Interesting Facts about 1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone

1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone is a fascinating compound that bridges the gap between organic chemistry and medicinal applications. Here are some intriguing aspects of this compound:

Chemical Structure and Significance

  • Pyrrole Derivative: This compound contains a pyrrole ring, which is known for contributing to the biological activity of various natural and synthetic compounds.
  • Functional Groups: It features a ketone functional group that plays a critical role in reactivity and potential pharmacological properties.
  • Substituents: The presence of both methyl and phenyl groups enhances its lipophilicity, making it interesting for drug design and synthesis.

Potential Biological Activities

Compounds containing pyrrole moieties have been studied for their various biological activities:

  • Antioxidant Properties: Many pyrrole derivatives exhibit antioxidant effects, which can be beneficial in preventing oxidative stress in biological systems.
  • Anti-cancer Potential: Some studies suggest that similar compounds have anti-cancer properties, opening avenues for further research into this specific derivative.
  • Neuroprotective Effects: Compounds like this one are being investigated for their neuroprotective abilities, potentially aiding in the treatment of neurodegenerative diseases.

Innovative Applications

The innovative potential of 1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone extends beyond pharmaceuticals:

  • Material Science: Its unique structure may lead to applications in the development of new materials with enhanced properties.
  • Catalysis: This compound could be a candidate for use in organic synthesis as a catalyst in various reactions.

In a nutshell, 1-(2-methyl-5-phenyl-1H-pyrrol-3-yl)ethanone stands as a reminder of the intricate relationship between chemical structure and function. As research continues, its potential implications for both science and medicine are a testament to the ever-evolving nature of organic chemistry.

Synonyms
BRN 0383810
1-(2-Methyl-5-phenyl-1H-pyrrol-3-yl)ethanone
ETHANONE, 1-(2-METHYL-5-PHENYL-1H-PYRROL-3-YL)-
13219-97-1
Ketone, (2-methyl-5-phenylpyrrol-3-yl) methyl
DTXSID50157412
5-21-08-00494 (Beilstein Handbook Reference)
DTXCID7079903