1-(2-morpholinoethyl)-3,4-dihydroquinolin-2-one

Identification

Molecular formula

C₁₅H₂₀N₂O₂

CAS number

74209-96-6

IUPAC name

1-(2-morpholinoethyl)-3,4-dihydroquinolin-2-one

State

At room temperature, this compound is usually in a solid state, maintaining its structural integrity while being handled or stored.

Melting point (Celsius)

183.00

Melting point (Kelvin)

456.15

Boiling point (Celsius)

385.00

Boiling point (Kelvin)

658.15

General information

Molecular weight

274.34g/mol

Molar mass

274.3410g/mol

Density

1.2105g/cm³

Appearence

This compound typically appears as a crystalline solid, which can range from off-white to pale yellow in color depending on its purity and specific batch.

Comment on solubility

Solubility of 1-(2-morpholinoethyl)-3,4-dihydroquinolin-2-one

The solubility of 1-(2-morpholinoethyl)-3,4-dihydroquinolin-2-one can significantly influence its application in various chemical and pharmaceutical processes. Here are key points to consider regarding its solubility:

Solvent Polarity: The compound's solubility is greatly affected by the polarity of the solvent used. Generally, polar solvents such as water can dissolve more polar compounds, while non-polar solvents favor non-polar substances.
Hydrogen Bonding: The presence of functional groups, especially the morpholine moiety, can enhance solubility through hydrogen bonding interactions with solvents.
Temperature Dependence: Like many organic compounds, the solubility of this compound may increase with temperature, allowing greater interaction with the solvent molecules.
pH Sensitivity: The solubility can also vary with pH, particularly in biological systems, as it may exist in different protonation states.
Crystalline vs. Amorphous Form: The physical form of the compound can impact its solubility; amorphous forms are typically more soluble than their crystalline counterparts.

In conclusion, the solubility of 1-(2-morpholinoethyl)-3,4-dihydroquinolin-2-one is a multifaceted property, and understanding the variables that affect it is crucial for its effective utilization in scientific applications. Adequate solubility can enhance the bioavailability of pharmaceutical formulations, thereby improving therapeutic efficacy.

Interesting facts

Interesting Facts about 1-(2-Morpholinoethyl)-3,4-dihydroquinolin-2-one

The compound 1-(2-morpholinoethyl)-3,4-dihydroquinolin-2-one is a fascinating member of the quinoline family, which is known for its diverse biological activities. Here are some notable points about this interesting compound:

Pharmacological Potential: This compound has garnered attention in medicinal chemistry due to its potential as a therapeutic agent. Its structural motif allows it to interact with various biological targets, which could lead to new treatments for diseases.
Mechanism of Action: The specific arrangement of the morpholinoethyl group in conjunction with the quinolone framework presents unique opportunities for designing molecules that can precisely modulate biological pathways.
Research Significance: Studies involving this compound often focus on its role in combating bacterial and viral infections. Research is ongoing to unlock its full potential, including the synthesis of analogs to improve efficacy and reduce toxicity.
Interdisciplinary Applications: Beyond pharmacology, this compound could find applications in the fields of materials science and agrochemicals, showcasing the versatility of quinoline derivatives.

As noted in a scientific review, compounds like this one "represent the intersection of chemistry and biology, where the design of new molecules can lead to profound innovations in health care."

Overall, 1-(2-morpholinoethyl)-3,4-dihydroquinolin-2-one is not just another chemical entity; it is a potential cornerstone for future discoveries in drug development and beyond.