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2'-nitroacetophenone

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Identification
Molecular formula
C8H7NO3
CAS number
577-27-5
IUPAC name
1-(2-nitrophenyl)ethanone
State
State

At room temperature, 2'-nitroacetophenone is typically in a solid state, characterized by its crystalline structure.

Melting point (Celsius)
76.50
Melting point (Kelvin)
350.00
Boiling point (Celsius)
297.00
Boiling point (Kelvin)
570.00
General information
Molecular weight
165.16g/mol
Molar mass
165.1560g/mol
Density
1.3150g/cm3
Appearence

2'-nitroacetophenone is a yellow crystalline solid. It forms needle-like crystals that emit a faint, yet characteristic aromatic odor.

Comment on solubility

Solubility of 1-(2-nitrophenyl)ethanone

1-(2-nitrophenyl)ethanone, also known as 2-nitroacetophenone, is a compound characterized by its interesting solubility properties. Understanding how well this compound dissolves in different solvents can provide insights into its potential applications and behavior in various chemical reactions.

This compound exhibits the following solubility characteristics:

  • Polar Solvents: 1-(2-nitrophenyl)ethanone is generally soluble in polar solvents such as water, methanol, and ethanol due to its own polar functional groups.
  • Non-Polar Solvents: It also finds solubility in non-polar solvents like hexane and benzene, highlighting its amphipathic nature.
  • Chemical Interactions: The presence of the nitro group can create favorable interactions with solvents that polar or hydrogen bond, significantly enhancing its solubility in those mediums.

According to solubility principles, "like dissolves like," which means that solubility can depend on the polarity of both the solute (1-(2-nitrophenyl)ethanone) and the solvent. Therefore, it’s crucial to consider these aspects when predicting solubility outcomes in different scenarios.

In conclusion, 1-(2-nitrophenyl)ethanone demonstrates a versatile solubility profile that allows it to be utilized in a range of chemical applications, making it a compound of interest in both industrial and laboratory settings.

Interesting facts

Interesting Facts About 1-(2-Nitrophenyl)ethanone

1-(2-Nitrophenyl)ethanone is an intriguing compound, both for its chemical properties and its applications. Here are some fascinating insights into this compound:

  • Chemical Structure: The structure features a nitrophenyl group attached to an ethanone moiety, indicating the presence of a carbonyl group (C=O) that contributes significantly to its reactivity. This unique arrangement allows it to participate in various chemical reactions, making it a versatile building block in organic synthesis.
  • Applications: This compound is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its reactivity enables the formation of other complex molecules, which are essential in drug development and other chemical processes.
  • Reactivity: 1-(2-Nitrophenyl)ethanone exhibits electrophilic properties due to the electron-withdrawing nitro group. This characteristic enhances its ability to undergo nucleophilic attack, enabling it to participate in reactions such as nucleophilic acyl substitution.
  • Historical Significance: The nitrophenyl group has a rich history in the development of dyes and pigments. Compounds like 1-(2-nitrophenyl)ethanone have played a critical role in the chemical industry, impacting everything from textiles to pharmaceuticals.
  • Research Potential: Researchers continue to explore the potential of this compound and its derivatives in various fields, including medicinal chemistry, materials science, and environmental studies. The ability to modify the nitrophenyl component provides an exciting avenue for creating novel compounds with specific properties.

In summary, 1-(2-nitrophenyl)ethanone is a compound that combines structure, reactivity, and versatility, making it a valuable subject of study in the realm of organic chemistry. Its applications and potential in research continue to drive interest among scientists and students alike.

Synonyms
2'-Nitroacetophenone
1-(2-Nitrophenyl)ethanone
2-Nitroacetophenone
O-NITROACETOPHENONE
2-Acetylnitrobenzene
Ethanone, 1-(2-nitrophenyl)-
CCRIS 2329
1-acetyl-2-nitrobenzene
NSC 3641
EINECS 209-414-8
UNII-52L53K4X3O
BRN 1102322
DTXSID6025723
52L53K4X3O
NSC-3641
NITROACETOPHENONE, O-
CCRIS-2329
DTXCID705723
METHYL O-NITROPHENYL KETONE
4-07-00-00655 (Beilstein Handbook Reference)
o-Nitrophenyl methyl ketone
O-ACETYLNITROBENZENE
O-NITROACETYLBENZENE
inchi=1/c8h7no3/c1-6(10)7-4-2-3-5-8(7)9(11)12/h2-5h,1h
sugxzlkudldtkx-uhfffaoysa-n
577-59-3
Acetophenone, 2'-nitro-
Methyl 2-nitrophenyl ketone
MFCD00007144
1-(2-Nitrophenyl)ethan-1-one
o-nitroacetophenon
NSC3641
2`-Nitroacetophenone
2'-nitro-acetophenone
1-(2-nitrophenyl)-ethanone
2'-Nitroacetophenone, 95%
MLS002415763
SCHEMBL334763
1-(2-nitro-phenyl)-ethanone
CHEMBL1881120
SCHEMBL14438210
STR04123
Tox21_200072
AKOS000120648
AC-2890
CS-W017892
FN26280
PS-3008
NCGC00091366-01
NCGC00091366-02
NCGC00257626-01
CAS-577-59-3
SMR001261211
SY003270
DB-014161
N0110
NS00033782
2 inverted exclamation mark -Nitroacetophenone
EN300-20910
Q27261014
F0001-1504
1-(2-Nitrophenyl)-ethanone;1-Acetyl-2-nitrobenzene;Methyl 2-nitrophenyl ketone