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Diclofenac

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Identification
Molecular formula
C14H11Cl2NO2
CAS number
15307-86-5
IUPAC name
1-[2,2-dichloro-1-(4-ethoxyphenyl)cyclopropyl]-4-ethoxy-benzene
State
State

At room temperature, diclofenac is in a solid state.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
445.50
Boiling point (Kelvin)
718.65
General information
Molecular weight
296.15g/mol
Molar mass
296.1480g/mol
Density
1.2800g/cm3
Appearence

Diclofenac is typically encountered as a white to slightly yellow crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of 1-[2,2-Dichloro-1-(4-ethoxyphenyl)cyclopropyl]-4-ethoxy-benzene

The solubility of 1-[2,2-dichloro-1-(4-ethoxyphenyl)cyclopropyl]-4-ethoxy-benzene is a fascinating topic due to its unique molecular structure and the influence of functional groups on its solubility characteristics.

  • Polarity: This compound is generally non-polar due to the presence of multiple ethoxy groups and its overall hydrocarbon framework, leading to limited solubility in polar solvents such as water.
  • Solvent Compatibility: It exhibits greater solubility in non-polar organic solvents such as hexane, dichloromethane, and toluene. This is attributed to the molecule's hydrophobic character.
  • Temperature Effects: The solubility of organic compounds often increases with temperature. Thus, heating the solvent may enhance the dissolution of this compound.
  • Functional Groups: The presence of ethoxy groups contributes to a balance between polar and non-polar characteristics, allowing some interaction with various solvents.

In summary, the solubility of 1-[2,2-dichloro-1-(4-ethoxyphenyl)cyclopropyl]-4-ethoxy-benzene can be characterized by its poor solubility in water but significant solubility in non-polar organic solvents, making it suitable for use in specific chemical environments.

Interesting facts

Interesting Facts about 1-[2,2-Dichloro-1-(4-Ethoxyphenyl)cyclopropyl]-4-ethoxy-benzene

1-[2,2-Dichloro-1-(4-ethoxyphenyl)cyclopropyl]-4-ethoxy-benzene is a fascinating compound that showcases the unique interplay of cyclopropyl groups and aromatic compounds. Here are some key insights:

  • Structural Complexity: This compound features a cyclopropane ring, which is known for its strain and unique reactivity. The incorporation of a cyclopropyl group often leads to intriguing chemical behaviors that differ from more common alkyl groups.
  • Dichlorination: The presence of two chlorine atoms in the structure adds a layer of functional versatility. Chlorinated compounds are widely studied for their biological activity and potential as pharmaceuticals or agrochemicals.
  • Aromatic Influence: With ethoxy substituents positioned on both the cyclopropyl and the para position of the benzene ring, this compound exhibits potential for stabilizing charge distribution and enhancing lipophilicity, which is crucial in drug design.
  • Biological Significance: Compounds like this one may exhibit significant activity in biological systems, including acting as inhibitors, facilitators, or synthetical agents. Their synthesis often leads to compounds of interest in medicinal chemistry.

As chemists continue to explore this compound, it serves as a reminder of the vast potential and rich chemical landscape found within organic compounds. The complex interplay of structural elements can lead to discoveries in both fundamental chemistry and practical applications. As Marie Curie once said, "Nothing in life is to be feared, it is only to be understood." Understanding compounds like this unlocks new possibilities in scientific advancement.

Synonyms
Monsanto CP-51543
ENT 27,391
22125-35-5
CP 51543
NSC 190983
CYCLOPROPANE, 1,1-DICHLORO-2,2-BIS(p-ETHOXYPHENYL)-
AI3-27391
1,1'-(2,2-Dichlorocyclopropylidene)bis(4-ethoxybenzene)
Benzene, 1,1'-(2,2-dichlorocyclopropylidene)bis(4-ethoxy-
DTXSID90176647
RefChem:336141
DTXCID2099138
1-[2,2-dichloro-1-(4-ethoxyphenyl)cyclopropyl]-4-ethoxybenzene
SCHEMBL11879135
1,1-di-(p-ethoxyphenyl)-2,2-dichlorocyclopropane