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Fenofibrate

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Identification
Molecular formula
C20H21Cl2O4
CAS number
49562-28-9
IUPAC name
1-[2,2-dichloro-1-(4-ethoxyphenyl)ethyl]-4-ethoxy-benzene
State
State

At room temperature, Fenofibrate is a solid. It is practically insoluble in water, slightly soluble in alcohols, and has better solubility in organic solvents such as methanol and acetone.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
527.70
Boiling point (Kelvin)
800.85
General information
Molecular weight
360.83g/mol
Molar mass
360.8320g/mol
Density
1.1903g/cm3
Appearence

Fenofibrate appears as a white crystalline powder. It is odorless and has a faint bitter taste. The compound is typically used in its pure form as a pharmaceutical product.

Comment on solubility

Solubility of 1-[2,2-dichloro-1-(4-ethoxyphenyl)ethyl]-4-ethoxy-benzene

The solubility of 1-[2,2-dichloro-1-(4-ethoxyphenyl)ethyl]-4-ethoxy-benzene is influenced by various factors, primarily its polarity and functional groups present in the structure. Here’s what you need to understand about its solubility characteristics:

  • Polarity: Given that the compound contains both ethoxy groups and dichloro substituents, its overall polarity can affect solubility in polar versus non-polar solvents.
  • Solvent Compatibility: This compound is more likely to be soluble in organic solvents such as:
    • Ethyl acetate
    • Toluene
    • Chloroform
  • Water Solubility: Due to the presence of large hydrophobic phenyl groups and ethoxy chains, it is *expected to have low solubility* in water.

In essence, while the various substituents can enhance interactions with non-polar environments, they may limit solubility in polar solvents. As a result, when working with this compound, *considering the solvent choice* is crucial for effective dissolution:

  1. For reactions or processes requiring solubility, opt for non-polar organic solvents.
  2. Avoid polar solvents like water unless specific conditions allow for solubility enhancement.

Understanding these solubility dynamics is key in applications involving 1-[2,2-dichloro-1-(4-ethoxyphenyl)ethyl]-4-ethoxy-benzene.

Interesting facts

Interesting Facts about 1-[2,2-Dichloro-1-(4-ethoxyphenyl)ethyl]-4-ethoxy-benzene

This compound is a fascinating example of how chemical structures can be designed for specific functionalities and applications. As a member of the organochlorine family, it showcases the versatility of chlorinated compounds in various fields. Here are some intriguing aspects:

  • Potential Applications: Compounds like this one have garnered attention in agricultural chemistry as potential pesticides or herbicides due to the biological activity often associated with chlorinated aromatic compounds.
  • Structural Complexity: The intricate structure of 1-[2,2-dichloro-1-(4-ethoxyphenyl)ethyl]-4-ethoxy-benzene reveals how modifications such as ethoxy groups can influence solubility and reactivity, making it a valuable subject of study in medicinal chemistry.
  • Mechanism of Action: Understanding how such compounds interact at the molecular level can shed light on their potential pharmacological effects, contributing to the development of new therapeutic agents.
  • Synthetic Routes: Chemists often employ innovative strategies to synthesize such complex molecules, and learning about the synthetic pathways can enhance our knowledge of organic synthesis.
  • Environmental Considerations: The use of chlorinated compounds presents questions regarding environmental persistence and toxicity, prompting ongoing research into safer alternatives.

As scientific research continues to expand, the exploration of compounds like 1-[2,2-dichloro-1-(4-ethoxyphenyl)ethyl]-4-ethoxy-benzene becomes not merely an academic pursuit but also a crucial endeavor for innovation and sustainability.

Synonyms
BRN 1993183
7388-32-1
Benzene, 1,1'-(2,2-dichloroethylidene)bis(4-ethoxy-
1,1'-(2,2-Dichloroethylidene)bis(4-ethoxybenzene)
DTXSID40224465
4-06-00-06691 (Beilstein Handbook Reference)
DTXCID40146956
1,1-bis-(p-ethoxyphenyl)-2,2-dichloroethane