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Metaraminol

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Identification
Molecular formula
C9H13NO3
CAS number
54-49-9
IUPAC name
1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-(2-hydroxyethylamino)ethanol
State
State

At room temperature, Metaraminol is a solid, specifically a crystalline powder, which is often used in solution form in medical applications.

Melting point (Celsius)
149.00
Melting point (Kelvin)
422.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
167.20g/mol
Molar mass
167.2040g/mol
Density
1.2028g/cm3
Appearence

Metaraminol appears as a white or almost white crystalline powder. It is usually odourless or has a very faint specific odour. It is soluble in water and quite soluble in alcohol.

Comment on solubility

Solubility of 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-(2-hydroxyethylamino)ethanol

The solubility of 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-(2-hydroxyethylamino)ethanol can be understood through several key factors:

  • Polarity: This compound features both hydrophilic (2-hydroxyethyl) and hydrophobic (benzodioxin) components, influencing its solubility in various solvents.
  • Hydrogen Bonding: The presence of hydroxyl groups enables strong hydrogen bonding with water, potentially enhancing solubility in polar solvents.
  • Temperature Dependence: Like many organic compounds, the solubility can vary significantly with temperature, often increasing at higher temperatures.

In general, this compound is likely to be:

  • Soluble in water: due to its ability to form hydrogen bonds.
  • Slightly soluble in organic solvents: particularly those that are polar.
  • Insoluble in non-polar solvents: as its hydrophobic characteristics dominate.

Overall, understanding the solubility profile of this compound is crucial for its practical applications in various fields, as the solubility will dictate its behavior in biological and chemical processes.

Interesting facts

Interesting Facts about 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-(2-hydroxyethylamino)ethanol

1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-(2-hydroxyethylamino)ethanol is a fascinating compound that boasts several unique characteristics and applications:

  • Structural Complexity: The compound features a complex fused ring system, characterized by a 1,4-benzodioxin moiety. This structural element is often associated with bioactive compounds, making it a subject of interest in pharmaceutical research.
  • Biological Activity: Compounds containing benzodioxin rings have been investigated for their potential anti-inflammatory and analgesic properties. Their unique interactions with biological systems can lead to significant therapeutic effects.
  • Amine Derivatives: The presence of the 2-(2-hydroxyethylamino) group enhances the compound's solubility in biological systems, making it an excellent candidate for drug formulation where bioavailability is essential.
  • Applications in Synthesis: This compound can serve as an intermediate in organic synthesis, particularly in the development of new pharmaceuticals. Its unique functional groups allow for further functionalization, resulting in a variety of derivatives.
  • Safety Considerations: As with many chemical compounds, proper handling and safety precautions are essential during its synthesis and application to avoid potential hazards associated with chemical exposure.

Ultimately, the intriguing properties of 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-(2-hydroxyethylamino)ethanol position it as an exciting subject for ongoing research in both medicinal chemistry and materials science.

Synonyms
13627-75-3
BRN 1384543
2691 I.S.
alpha-(((2-Hydroxyethyl)amino)methyl)-1,4-benzodioxan-2-methanol
2-(1-Idrossi-2-ethanolammino)etil-1,4-benzodiossano [Italian]
1,4-BENZODIOXAN-2-METHANOL, alpha-(((2-HYDROXYETHYL)AMINO)METHYL)-
2-(1-Idrossi-2-ethanolammino)etil-1,4-benzodiossano
1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-(2-hydroxyethylamino)ethanol
alpha-[[(2-Hydroxyethyl)amino]methyl]-1,4-benzodioxane-2-methanol
DTXSID00929308
1-(2,3-Dihydro-1,4-benzodioxin-2-yl)-2-[(2-hydroxyethyl)amino]ethan-1-ol