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Venlafaxine

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Identification
Molecular formula
C17H27NO2
CAS number
93413-69-5
IUPAC name
1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-[3-methoxypropyl(methyl)amino]ethanol
State
State

At room temperature, venlafaxine is typically in a solid state, commonly found in its pharmaceutical dosage forms such as tablets or capsules for oral administration.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
454.80
Boiling point (Kelvin)
727.95
General information
Molecular weight
277.41g/mol
Molar mass
277.4080g/mol
Density
1.1327g/cm3
Appearence

Venlafaxine is a white to off-white crystalline solid. It is soluble in water and appears in tablet or capsule form for pharmaceutical use.

Comment on solubility

Solubility of 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-[3-methoxypropyl(methyl)amino]ethanol

The solubility of organic compounds can be greatly influenced by their molecular structure and functional groups. For 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-[3-methoxypropyl(methyl)amino]ethanol, its unique configuration introduces a variety of factors that affect its solubility. Here are some key points to consider:

  • Polarity: The presence of functional groups such as the hydroxyl (-OH) and amino (-NH) groups increases the polarity, which can enhance solubility in polar solvents like water.
  • Hydrophobic Regions: The aromatic and long hydrocarbon chains introduce hydrophobic characteristics, suggesting that this compound may also dissolve well in non-polar organic solvents.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds with solvent molecules can significantly impact solubility. Compounds capable of engaging in extensive hydrogen bonding tend to have increased solubility in polar solvents.

In conclusion, the solubility of 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-[3-methoxypropyl(methyl)amino]ethanol likely varies depending on the solvent used. As a general guideline:

  • It may exhibit good solubility in water due to the polar groups.
  • It could also be soluble in common organic solvents such as ethanol or acetone.

Further experimental studies are advisable to precisely quantify its solubility across different solvents, thereby providing deeper insights into its potential applications and behaviors in various environments.

Interesting facts

Interesting Facts about 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-[3-methoxypropyl(methyl)amino]ethanol

This compound, known for its complex molecular structure, offers a fascinating glimpse into the world of organic chemistry and medicinal applications. It features a benzodioxin moiety, which is a characteristic element in various bioactive compounds. Here are some key points that highlight its significance:

  • Potential Therapeutic Applications: Compounds with a benzodioxin core have been studied for their possible roles as pharmaceutical agents, particularly in treating neurological disorders and as anti-inflammatory drugs.
  • Structure-Activity Relationship: The combination of the dioxin ring with amine functionalities can significantly affect biological activity, making it an interesting subject for medicinal chemistry research.
  • Synthetic Pathways: The synthesis of this compound involves intricate organic reactions, showcasing the art of chemical synthesis. Chemists utilize advanced techniques such as palladium-catalyzed coupling reactions to construct the benzodioxin framework.
  • Research Significance: Recent studies have indicated that compounds with similar structures may possess neuroprotective properties, contributing to research in neuropharmacology and potential therapies.

It's essential to continue exploring the properties and applications of this compound and its derivatives in the field of chemistry. Each modification at various locations of the molecule could lead to exciting new findings and advancements in drug development.

As the field of medicinal chemistry evolves, the exploration of complex compounds like this one remains critical. As one researcher aptly put it, "Understanding the relationship between structure and function in organic compounds opens the door to revolutionary discoveries in medicine."

Synonyms
13627-81-1
2800 I.S.
BRN 1389082
alpha-((N-(3-Methoxypropyl)methylamino)methyl)-1,4-benzodioxan-2-methanol
1,4-BENZODIOXAN-2-METHANOL, alpha-(((3-METHOXYPROPYL)METHYLAMINO)METHYL)-
2-(1-Idrossi-2-(N-metil-N-gamma-metossipropilammino))etil-1,4-benzodiossano [Italian]
2-(1-Idrossi-2-(N-metil-N-gamma-metossipropilammino))etil-1,4-benzodiossano
1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-[3-methoxypropyl(methyl)amino]ethanol
alpha-[[(3-Methoxypropyl)methylamino]methyl]-1,4-benzodioxane-2-methanol
DTXSID50929313
1-(2,3-Dihydro-1,4-benzodioxin-2-yl)-2-[(3-methoxypropyl)(methyl)amino]ethan-1-ol