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3,4-Methylenedioxyamphetamine (MDA)

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Identification
Molecular formula
C10H13NO2
CAS number
4764-17-4
IUPAC name
1-(2,3-dihydro-1,4-benzodioxin-3-yl)ethanamine
State
State

At room temperature, MDA is most commonly found as a solid, either in its pure powdered form or as crystalline tablets. It is also known to be used in pharmaceutical and illicit environments in pill form.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
191.00
Boiling point (Kelvin)
464.15
General information
Molecular weight
179.22g/mol
Molar mass
179.2170g/mol
Density
1.1230g/cm3
Appearence

MDA typically appears as an off-white to beige crystalline powder.

Comment on solubility

Solubility of 1-(2,3-dihydro-1,4-benzodioxin-3-yl)ethanamine

The solubility of 1-(2,3-dihydro-1,4-benzodioxin-3-yl)ethanamine is influenced by several factors due to its complex structure. Here are some important points to consider:

  • Polarity: The polarity of the compound plays a significant role in its solubility. Compounds with polar functional groups tend to dissolve well in polar solvents, such as water.
  • Hydrogen Bonding: The presence of nitrogen and oxygen atoms in the structure can facilitate hydrogen bonding, enhancing its solubility in polar solvents.
  • Molecular Weight: The relatively low molecular weight of this compound might suggest favorable solubility characteristics in organic solvents.
  • Application in Solvents: Generally, it can be expected that 1-(2,3-dihydro-1,4-benzodioxin-3-yl)ethanamine may show solubility in organic solvents such as ethanol or methanol.
  • Miscibility: It is likely that the compound has limited water solubility; however, detailed experimental solubility data is needed for precise information.

To sum up, while the precise solubility of 1-(2,3-dihydro-1,4-benzodioxin-3-yl)ethanamine in various solvents requires empirical testing, its structural features suggest a tendency towards solubility in polar organic solvents as a consequence of molecular interactions.

Interesting facts

Interesting Facts about 1-(2,3-dihydro-1,4-benzodioxin-3-yl)ethanamine

1-(2,3-dihydro-1,4-benzodioxin-3-yl)ethanamine is a compound that embodies a fascinating blend of organic chemistry and medicinal applications. Here are some intriguing insights:

  • Structural Characteristics: This compound features a unique benzo[d][1,3]dioxole core, which contributes to its interesting chemical properties. The presence of both dioxole and ethylamine functionalities enhances its reactivity and potential physiological interactions.
  • Biological Significance: Compounds with similar structures have garnered attention for their potential therapeutic effects. They may possess properties that contribute to neuroprotection and mood enhancement, making them subjects of interest in the field of pharmacology.
  • Synthesis and Derivatives: The synthesis of this compound can serve as a platform for developing derivatives that could modulate various biological activities. This versatility can lead to novel drugs aimed at treating neurological disorders.
  • Potential Applications: Research into similar compounds suggests that they may play roles in:
    • Antidepressant therapy
    • Neuroprotective agents
    • Antioxidant action
  • Research Directions: Ongoing studies may uncover more about the mechanisms of action and possible therapeutic applications, making it an exciting area for both academic and commercial research.

In conclusion, 1-(2,3-dihydro-1,4-benzodioxin-3-yl)ethanamine exemplifies how organic compounds can hold the key to understanding biological mechanisms and developing new therapeutic strategies. As research continues, this compound could pave the way for significant advancements in medicine.

Synonyms
2469-18-3
2-(1-Aminoethyl)-1,4-benzodioxane
1-(1,4-benzodioxan-2-yl)ethylamine
1-(2,3-dihydro-1,4-benzodioxin-3-yl)ethanamine
1-(2,3-dihydro-1,4-benzodioxin-2-yl)ethan-1-amine
1,4-Benzodioxin-2-methanamine, 2,3-dihydro-alpha-methyl-
1-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)ethan-1-amine
BRN 1345378
(1r)-1-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)ethan-1-amine
1,4-BENZODIOXAN, 2-(1-AMINOETHYL)-
1-(2,3-dihydro-1,4-benzodioxin-2-yl)ethanamine
1372912-56-5
Oprea1_855066
SCHEMBL4461156
DTXSID70947630
AANTWDPFFAREMQ-UHFFFAOYSA-N
STK555959
AKOS005481977
EN300-1851284