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2-(2,3-Dihydrobenzofuran-2-yl)-N-methyl-ethanamine

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Identification
Molecular formula
C11H15NO
CAS number
133053-19-3
IUPAC name
1-(2,3-dihydrobenzofuran-2-yl)-N-methyl-methanamine
State
State

The compound is typically in a liquid state at room temperature. It has a relatively low melting point, which keeps it from being solid under standard conditions.

Melting point (Celsius)
-12.10
Melting point (Kelvin)
261.05
Boiling point (Celsius)
143.80
Boiling point (Kelvin)
416.95
General information
Molecular weight
179.25g/mol
Molar mass
179.2500g/mol
Density
1.1750g/cm3
Appearence

2-(2,3-Dihydrobenzofuran-2-yl)-N-methyl-ethanamine typically appears as a colorless to light yellow liquid that may have a characteristic odor, depending on its purity and any impurities present.

Comment on solubility

Solubility of 1-(2,3-dihydrobenzofuran-2-yl)-N-methyl-methanamine

The solubility of 1-(2,3-dihydrobenzofuran-2-yl)-N-methyl-methanamine can be influenced by various factors. This compound is characterized by its complex aromatic structure, which suggests a few key points regarding its solubility:

  • Polarity: Due to the presence of an amine group, the molecule may exhibit some polar characteristics, allowing it to interact with polar solvents like water.
  • Hydrophobic Regions: The dihydrobenzofuran moiety generates hydrophobic properties that might hinder substantial solubility in aqueous environments.
  • Solvent Compatibility: It is likely to show better solubility in organic solvents, such as ethanol, methanol, or dimethyl sulfoxide (DMSO), compared to water.

When considering the solubility profile, it is essential to recognize that:

  1. Temperature variations can significantly affect solubility; higher temperatures generally increase solubility in organic solvents.
  2. pH levels may also influence the degree of ionization of the amine, further impacting solubility.

Overall, the solubility of 1-(2,3-dihydrobenzofuran-2-yl)-N-methyl-methanamine is expected to be moderate in polar solvents but may exhibit greater solubility in non-polar organic solvents, making it versatile for various applications in chemical processes.

Interesting facts

Introduction to 1-(2,3-dihydrobenzofuran-2-yl)-N-methyl-methanamine

1-(2,3-dihydrobenzofuran-2-yl)-N-methyl-methanamine is an intriguing chemical compound with a complex structure that piques the interest of chemists and researchers alike. It belongs to the class of organic compounds known as amines and possesses distinct characteristics that make it worthy of exploration.

Key Features

  • Structural Diversity: The compound features a benzofuran ring, which contributes to its unique physical and chemical properties. Benzofurans often exhibit interesting biological activity, making this compound a candidate for pharmacological studies.
  • Potential Applications: Due to its structure, this compound could serve as a scaffold for the development of new drugs. Compounds derived from benzofurans are known for their antidepressant, antitumor, and anti-inflammatory properties.
  • Research Interest: Scientists have begun to explore the potential interactions between this compound and biological receptors, demonstrating its possible relevance in medicinal chemistry.

Biological Significance

The structural motifs in 1-(2,3-dihydrobenzofuran-2-yl)-N-methyl-methanamine allow for intriguing interactions at the molecular level. Studies have suggested that compounds with similar structures could exhibit:

  • Neuroactive properties that may influence neurotransmitter systems.
  • Anticancer activity through mechanisms involving apoptosis and cell cycle regulation.
  • Potential in treating mood disorders by modulating serotonin and dopamine pathways.

Conclusion

In summary, 1-(2,3-dihydrobenzofuran-2-yl)-N-methyl-methanamine is a fascinating compound that stands at the intersection of organic chemistry and pharmacology. As research continues to unfold regarding its properties and applications, it holds promise for future discoveries in therapeutic agents and chemical biology.

Synonyms
21130-01-8
EPS 4032
2,3-Dihydro-N-methyl-2-benzofuranmethanamine
2-Methylaminomethyl-2,3-dihydrobenzofuran
RefChem:88250
2-Methylaminomethyl coumaran
(2,3-Dihydro-benzofuran-2-ylmethyl)-methyl-amine
1-(2,3-Dihydrobenzofuran-2-yl)-N-methylmethanamine
1-(2,3-dihydro-1-benzofuran-2-yl)-N-methylmethanamine
MFCD00460575
(2,3-dihydro-1-benzofuran-2-ylmethyl)(methyl)amine
BRN 1283431
SCHEMBL1485141
2-BENZOFURANMETHYLAMINE, 2,3-DIHYDRO-N-METHYL-
DTXSID50943453
(7-methoxy-2,3-dihydro-1-benzofuran-2-yl)methylazanium chloride
AKOS000558650
AKOS022185000
SB35368
DB-257483
CS-0449700
5-18-09-00636 (Beilstein Handbook Reference)
1-(2,3-dihydrobenzofuran-2-yl)-N-methyl-methanamine
[(2,3-dihydro-1-benzofuran-2-yl)methyl](methyl)amine
F8885-5886