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3,5-Diiodothyronine

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Identification
Molecular formula
C9H7I2NO3
CAS number
3615-08-5
IUPAC name
1-(2,3-dihydroxypropyl)-3,5-diiodo-pyridin-4-one
State
State

At room temperature, 3,5-Diiodothyronine is typically a solid substance.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
444.96g/mol
Molar mass
444.9370g/mol
Density
3.1100g/cm3
Appearence

3,5-Diiodothyronine typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 1-(2,3-dihydroxypropyl)-3,5-diiodo-pyridin-4-one

The solubility of 1-(2,3-dihydroxypropyl)-3,5-diiodo-pyridin-4-one can be insightful due to its unique chemical structure. This compound, known for its functional groups, demonstrates certain solubility characteristics that can be discussed as follows:

  • Polar vs Non-polar: The presence of the –OH (hydroxyl) groups contributes to the compound's polar nature, enhancing its solubility in polar solvents like water.
  • Hydrogen Bonding: The hydroxyl groups may facilitate hydrogen bonding with water, thus increasing solubility.
  • Iodine Atoms: The –I (iodine) substituents may influence solubility through van der Waals interactions but are generally considered less favorable for solubility in polar solvents compared to the hydroxyl groups.
  • Solvent Compatibility: While polar solvents could dissolve this compound effectively, its solubility might be limited in non-polar solvents due to the opposing polarities.

In practical applications, understanding the solubility of 1-(2,3-dihydroxypropyl)-3,5-diiodo-pyridin-4-one is essential, as it can affect factors such as:

  1. The compound's bioavailability in pharmaceutical formulations.
  2. Its effectiveness in various chemical reactions where solubility plays a critical role.
  3. The ease of purification and extraction in laboratory settings.

Overall, while challenges with solubility may arise due to structural characteristics, the presence of polar functional groups provides a pathway for improved interaction with suitable solvents.

Interesting facts

Interesting Facts about 1-(2,3-dihydroxypropyl)-3,5-diiodo-pyridin-4-one

1-(2,3-dihydroxypropyl)-3,5-diiodo-pyridin-4-one is a fascinating compound that has attracted attention in various fields, particularly in medicinal chemistry. Here are some notable aspects:

  • Pharmacological Potential: This compound belongs to the class of pyridinones, which are known for their diverse biological activities. Research has shown that such compounds may exhibit anti-inflammatory, antimicrobial, and even anticancer properties.
  • Structure and Function: The unique structure of this compound, with its diiodo substitutions and hydroxyl groups, contributes to its reactivity and potential interactions with biological targets. The presence of multiple functional groups enhances its prospects for varied applications.
  • Role as a Ligand: Due to its ability to coordinate with metal ions, this compound can serve as a ligand in coordination chemistry, potentially forming complexes that are useful in catalysis or drug design.
  • Research Interests: Scientists have been intrigued by how the diiodo groups influence the compound's physical and chemical properties. They are particularly interested in studying how these modifications can enhance biological activity or selectivity toward specific targets.
  • Natural Inspiration: The design and synthesis of similar compounds often draw inspiration from natural products that exhibit potent biological activities, showcasing the interplay between synthetic chemistry and nature.

Overall, 1-(2,3-dihydroxypropyl)-3,5-diiodo-pyridin-4-one stands as a prime example of how small modifications in chemical structure can lead to significant changes in biological behavior, making it a compound of keen interest in ongoing scientific research.

Synonyms
IOPYDOL
5579-92-0
Iopidol
Iopidolo
Iopydolum
Jopydolum
Iopidolo [DCIT]
Iopidol [INN-Spanish]
Iopydolum [INN-Latin]
Iopydol (USAN)
UNII-T4661K682A
Iopydol [USAN:INN:BAN:JAN]
IOPYDOL [INN]
IOPYDOL [USAN]
IOPYDOL [MI]
EINECS 226-968-6
IOPYDOL [MART.]
IOPYDOL [WHO-DD]
T4661K682A
4(1H)-Pyridinone, 1-(2,3-dihydroxypropyl)-3,5-diiodo-
4(1H)-Pyridone, 1-(2,3-dihydroxypropyl)-3,5-diiodo-
Iopidol (INN-Spanish)
Iopydolum (INN-Latin)
IOPYDOL (MART.)
1-(2,3-DIHYDROXYPROPYL-3,5-DIIODO-4(1H)-PYRIDONE
1-(2,3-dihydroxypropyl)-3,5-diiodo-1,4-dihydropyridin-4-one
226-968-6
1-(2,3-dihydroxypropyl)-3,5-diiodopyridin-4-one
1-(2,3-Dihydroxypropyl)-3,5-diiodo-4(1H)-pyridone
1-(2,3-dihydroxypropyl)-3,5-diiodopyridin-4(1H)-one
4(1H)-Pyridinone, 1-(2,3-dihydroxypropyl)-3,5-diiodo-; 4(1H)-Pyridone, 1-(2,3-dihydroxypropyl)-3,5-diiodo- (7CI,8CI); 1-(2,3-Dihydroxypropyl)-3,5-diiodo-4(1H)-pyridone; 1-(2,3-Dihydroxypropyl)-3,5-diiodo-4-pyridone; Iopydol; N-(2,3-Dihydroxypropyl)-3,5-diiodo-4-pyridone
SCHEMBL668231
CHEMBL2104393
DTXSID90863565
CHEBI:136000
TZADDXVKYWMEHX-UHFFFAOYSA-N
FAA57992
AKOS034130849
DB13389
NS00044246
D04586
EN300-1272849
Q6063905
Z1269228101