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1-(2,3,4-trihydroxyphenyl)ethanone

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Identification
Molecular formula
C8H8O4
CAS number
152-01-6
IUPAC name
1-(2,3,4-trihydroxyphenyl)ethanone
State
State

At room temperature, 1-(2,3,4-trihydroxyphenyl)ethanone is solid.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.00
Boiling point (Celsius)
316.00
Boiling point (Kelvin)
589.00
General information
Molecular weight
168.15g/mol
Molar mass
168.1470g/mol
Density
1.4870g/cm3
Appearence

This compound is typically found as an off-white to light brown crystalline powder.

Comment on solubility

Solubility of 1-(2,3,4-trihydroxyphenyl)ethanone

1-(2,3,4-trihydroxyphenyl)ethanone is a compound characterized by its multiple hydroxyl groups, which significantly influence its solubility properties. The presence of these hydroxy groups enhances its ability to form hydrogen bonds with water, thus increasing its solubility in polar solvents.

Key Points about Solubility:

  • In Water: The compound is expected to have good solubility in water due to its three hydroxyl (−OH) groups, which can interact favorably with water molecules.
  • In Organic Solvents: It may exhibit limited solubility in non-polar organic solvents owing to the hydrophilic nature of the hydroxyl groups.
  • Temperature Effects: Solubility may increase with temperature, a common phenomenon observed in many organic compounds.
  • pH Dependence: The solubility can be influenced by pH, especially if the compound can exist in ionized forms under certain conditions.

In summary, the solubility of 1-(2,3,4-trihydroxyphenyl)ethanone is primarily driven by its capability to engage in hydrogen bonding and the environmental factors such as temperature and pH. This makes it potentially useful in various applications where aqueous solubility is critical.

Interesting facts

Interesting Facts about 1-(2,3,4-trihydroxyphenyl)ethanone

1-(2,3,4-trihydroxyphenyl)ethanone, often referred to in the scientific community for its unique structural features, is an intriguing compound with a variety of applications. Here are some noteworthy aspects of this compound:

  • Bioactivity: This compound is notable for its potential biological activities, including antioxidant properties. Its phenolic hydroxyl groups are known to play a crucial role in scavenging free radicals, which can undermine cellular integrity.
  • Applications in Research: In medicinal chemistry, 1-(2,3,4-trihydroxyphenyl)ethanone has been studied for its anticancer and anti-inflammatory properties. Researchers are particularly interested in its capability to modulate various biochemical pathways.
  • Synthesis: The synthesis of this compound typically involves multi-step organic reactions, showcasing the complexity of its formation. Chemists often explore various methods to improve yield and purity.
  • Derivative Studies: Due to its structure, derivatives of 1-(2,3,4-trihydroxyphenyl)ethanone are also of interest. Modifying the hydroxyl groups or the ethanone moiety can result in compounds with enhanced or varying biological activities.
  • Educational Value: For chemistry students, this compound serves as an excellent example of how organic molecules can exhibit diverse reactivity and interactivity due to functional group variations.

As noted by researchers, "Understanding compounds like 1-(2,3,4-trihydroxyphenyl)ethanone is essential not only for academic pursuits but for developing practical applications in pharmaceuticals and beyond." This emphasizes the importance of studying such compounds in advancing scientific knowledge.

In summary, 1-(2,3,4-trihydroxyphenyl)ethanone is more than just a chemical formula. It represents a class of compounds that bridge organic chemistry and the biological sciences, making it a fascinating subject for both study and application.

Synonyms
Gallacetophenone
528-21-2
1-(2,3,4-Trihydroxyphenyl)ethanone
2',3',4'-TRIHYDROXYACETOPHENONE
Galloacetophenone
Alizarin Yellow C
Alizarine Yellow C
Ethanone, 1-(2,3,4-trihydroxyphenyl)-
4-Acetylpyrogallol
C.I. 57000
NSC 66553
Acetophenone, 2',3',4'-trihydroxy-
2,3,4-Trihydroxyacetophenone oxime
EINECS 208-430-2
C70E921C4P
NSC-66553
GALLACETOPHENONE [MI]
DTXSID2060179
DTXCID3041297
208-430-2
inchi=1/c8h8o4/c1-4(9)5-2-3-6(10)8(12)7(5)11/h2-3,10-12h,1h
2,3,4-Trihydroxyacetophenone
MFCD00002193
1-(2,3,4-Trihydroxyphenyl)ethan-1-one
CHEMBL242540
1-(2,3,4-trihydroxy-phenyl)-ethanone
Gallacetophenon
UNII-C70E921C4P
Acetophenone, 2,3,4-trihydroxy-
Gallacetophenone, 97%
2,4-Trihydroxyacetophenone
WLN: QR BQ CQ DV1
SCHEMBL105704
2,4-Trihydroxyacetophenone oxime
Acetophenone,3',4'-trihydroxy-
Ethanone,3,4-trihydroxyphenyl)-
CHEBI:193439
ALBB-015601
NSC66553
Acetophenone, 2,3,4-trihydroxy-,
2', 3', 4'-trihydroxyacetophenone
BBL027373
BDBM50234652
STK519460
AKOS002214745
2'',3'',4''-Trihydroxyacetophenone
BS-3913
FT67476
BP-12555
SY048565
CS-0155152
NS00021192
T1198
2\',3\',4\'-TRIHYDROXYACETOPHENONE
EN300-203349
Q5518813
Z57124116
2 inverted exclamation mark ,3 inverted exclamation mark ,4 inverted exclamation mark -Trihydroxyacetophenone