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2,4,5-Trimethoxyamphetamine

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Identification
Molecular formula
C12H19NO3
CAS number
2012-31-1
IUPAC name
1-(2,4,5-trimethoxyphenyl)propan-2-amine
State
State

At room temperature, 2,4,5-Trimethoxyamphetamine is typically found as a solid.

Melting point (Celsius)
198.50
Melting point (Kelvin)
471.65
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
225.29g/mol
Molar mass
211.2760g/mol
Density
1.0030g/cm3
Appearence

2,4,5-Trimethoxyamphetamine is typically a crystalline solid. It may appear as an off-white to slightly yellowish powder, depending on its purity and form. In different contexts, it may be found in other forms or mixed with other substances.

Comment on solubility

Solubility of 1-(2,4,5-trimethoxyphenyl)propan-2-amine

The solubility of 1-(2,4,5-trimethoxyphenyl)propan-2-amine, often known as a member of the phenethylamine class, can be an intriguing topic of discussion. This compound exhibits specific solubility characteristics that are influenced by its molecular structure. Key factors that determine its solubility include:

  • Polarity: The presence of the highly polar amine functional group contributes to its solubility in polar solvents.
  • Substituents: The trimethoxy group on the aromatic ring can affect overall solubility, generally increasing hydrophobic interactions, which may lead to lower solubility in water.
  • pH Sensitivity: The solubility of amines can be significantly influenced by the pH of the solution. In an acidic environment, protonation of the amine group can enhance solubility.

Quotes from the literature reveal that solubility can vary widely based on formulation and environmental conditions, highlighting the importance of conducting solubility tests under specific conditions to gain accurate insights.

In summary, while 1-(2,4,5-trimethoxyphenyl)propan-2-amine may show moderate solubility in polar organic solvents and reduced solubility in water, the exact solubility profile can only be understood through systematic study and experimental data. Each factor plays a vital role in predicting how this compound interacts within different solvent systems.

Interesting facts

Interesting Facts About 1-(2,4,5-trimethoxyphenyl)propan-2-amine

1-(2,4,5-trimethoxyphenyl)propan-2-amine, also known by its common names and characterizations, is an interesting compound that diverges into the realms of medicinal chemistry and psychoactive research.

Chemical Characteristics

This compound belongs to a class of chemicals often referred to as analogs of amphetamines. Its chemical structure contributes to a variety of intriguing properties, such as:

  • Potential psychoactive effects: The compound shares structural similarities with compounds known for their psychoactive properties, making it a subject of interest for researchers studying the effects of molecular variations on human receptors.
  • Molecular complexity: The presence of three methoxy groups on the phenyl ring alters the electron distribution and polarity, which can illustrate the significance of subtle molecular changes.
  • Research potential: Due to its structure, it is studied not only for its pharmacological properties but also for its implications in understanding neurochemistry.

Research and Applications

A fascinating aspect of 1-(2,4,5-trimethoxyphenyl)propan-2-amine is its exploration in medicinal fields:

  • Psychopharmacology: This compound can serve as a model for developing new treatments for mood disorders, as researchers aim to delineate the pathways activated by such compounds.
  • Neuroscience studies: By observing its interaction with neurotransmitter receptors, scientists can glean insights into depression and anxiety treatments.
  • Analog studies: It opens avenues for studying structural analogs, comparing the effects of variations in functional groups and substituent locations.

In the words of a prominent chemist: "The key to innovation lies in the exploration of the uncharted territories of molecular structures." Exploring compounds like 1-(2,4,5-trimethoxyphenyl)propan-2-amine allows us to push the boundaries of what is known in chemical sciences, facilitating advancements in both therapeutic and recreational contexts. Accordingly, it remains pivotal in ongoing research aimed at unlocking new treatments with minimized side effects while maximizing efficacy.

Synonyms
2,4,5-Trimethoxyamphetamine
1083-09-6
2,4,5-Trimethoxyphenylisopropylamine
713Z3SL0TJ
Phenethylamine, 2,4,5-trimethoxy-alpha-methyl-
2,4,5-Trimethoxy-alpha-methylbenzeneethanamine
DTXSID00874364
TMA-2 cpd
RefChem:908691
DTXCID001012492
1-(2,4,5-trimethoxyphenyl)propan-2-amine
TMA-2
2,4,5-TRIMETHOXYAMPHETAMIN
2,4,5-Trimethoxy-alpha-methylphenethylamine
Phenethylamine, 2,4,5-trimethoxy-.alpha.-methyl-
CHEMBL8389
Phenethylamine, .alpha.-methyl-2,4,5-trimethoxy-
UNII-713Z3SL0TJ
Phenethylamine, alpha-methyl-2,4,5-trimethoxy-
SCHEMBL398580
Benzeneethanamine, 2,4,5-trimethoxy-.alpha.-methyl-
SCHEMBL29425260
TVSIMAWGATVNGK-UHFFFAOYSA-N
Benzeneethanamine, 2,4,5-trimethoxy-alpha-methyl-, (+-)-
BAA08309
BDBM50005253
AKOS000161117
DL-2,4,5-TRIMETHOXYAMPHETAMINE
22199-15-1
J13.143A
PD020028
2,4,5-TRIMETHOXYAMPHETAMINE, DL-
DB-226815
NS00017333
2,4,5-Trimethoxy-.alpha.-methylphenethylamine
C22746
1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylamine
1-Methyl-2-(2,4,5-trimethoxyphenyl)ethylamine #
(+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylamine
(+/-)-1-(2,4,5-TRIMETHOXYPHENYL)-2-AMINOPROPANE
1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylamine(2,4,5-TMA)
Benzeneethanamine,2,4,5-trimethoxy-.alpha.-methyl-(.+/-.)-