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Mesityl oxide

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Identification
Molecular formula
C10H12O
CAS number
141-79-7
IUPAC name
1-(2,4,6-trimethylphenyl)ethanone
State
State

At room temperature, mesityl oxide is in a liquid state. It has a low melting point which means it remains liquid even in cooler environments.

Melting point (Celsius)
-53.00
Melting point (Kelvin)
220.20
Boiling point (Celsius)
129.50
Boiling point (Kelvin)
402.70
General information
Molecular weight
148.20g/mol
Molar mass
148.2040g/mol
Density
0.9865g/cm3
Appearence

Mesityl oxide is a clear, colorless to pale yellow liquid with a strong peppermint- or acetone-like smell. It is flammable and volatile, making it important to handle with care, especially under standard conditions.

Comment on solubility

Solubility of 1-(2,4,6-trimethylphenyl)ethanone

The solubility of 1-(2,4,6-trimethylphenyl)ethanone can be influenced by several factors due to its chemical structure. This compound, which features a bulky trimethylphenyl group, generally presents interesting solubility characteristics:

  • Solvent Interaction: It tends to be more soluble in non-polar solvents due to its hydrophobic nature. Common non-polar solvents include hexane and benzene.
  • Weak Polar Solvents: It may show moderate solubility in weakly polar solvents such as ethyl acetate or dichloromethane.
  • Water Solubility: However, the solubility in water is quite poor, primarily because water is a polar solvent and 1-(2,4,6-trimethylphenyl)ethanone is mostly non-polar.

In general, the bulky and hydrophobic trimethyl group significantly affects the solubility profile:

  • The steric hindrance from the trimethyl groups limits the interaction with polar solvents.
  • Thus, it restricts its ability to dissolve in water, leading to a low solubility in aqueous solutions.

In conclusion, the solubility of 1-(2,4,6-trimethylphenyl)ethanone is primarily dictated by its non-polar character and interaction with various solvents, favoring the non-polar over the polar environments. As a rule of thumb, remember: *“Like dissolves like.”*

Interesting facts

Interesting Facts about 1-(2,4,6-trimethylphenyl)ethanone

1-(2,4,6-trimethylphenyl)ethanone, commonly referred to as an aromatic ketone, is a fascinating compound with several intriguing characteristics:

  • Aromatic Compound: This compound belongs to the family of aromatic ketones, which are pivotal in various synthetic organic reactions due to their stability and reactivity.
  • Versatile Applications: It is used extensively in the fragrance and flavor industry, serving as a key ingredient in the synthesis of various perfumes and food additives.
  • Role in Organic Synthesis: 1-(2,4,6-trimethylphenyl)ethanone acts as a crucial intermediate in organic chemistry, facilitating the production of more complex organic molecules.
  • Biological Significance: Some studies suggest that the compounds derived from ketones like this one may exhibit biological activities, potentially leading to applications in pharmaceuticals.
  • Unique Structure: Its structure features a highly substituted aromatic ring, which contributes to its chemical properties and interactions. The three methyl groups on the phenyl ring induce specific steric effects that can influence reactivity.
  • Resonance Stabilization: The ketone functional group allows for resonance stabilization of the molecule, enhancing its stability compared to non-aromatic ketones.
  • Industrial Relevance: Beyond its role in aromas, this compound is significant in the manufacturing of dyes, pigments, and certain types of plastics.

In summary, 1-(2,4,6-trimethylphenyl)ethanone is more than just a molecule; it stands at the intersection of chemistry and various industries, showcasing the importance of structural nuances in determining functionality and application.

Synonyms
1667-01-2
2',4',6'-TRIMETHYLACETOPHENONE
Acetomesitylene
Ethanone, 1-(2,4,6-trimethylphenyl)-
Mesityl methyl ketone
Acetophenone, 2',4',6'-trimethyl-
1,3,5-Trimethyl-2-acetylbenzene
NSC 65636
AI3-11164
EINECS 216-783-9
DTXSID1061865
DTXCID2035350
Acetophenone, 2',4',6'-trimethyl-(8CI)
216-783-9
inchi=1/c11h14o/c1-7-5-8(2)11(10(4)12)9(3)6-7/h5-6h,1-4h
1-Mesitylethanone
Acetylmesitylene
1-(2,4,6-trimethylphenyl)ethanone
2,4,6-trimethylacetophenone
Methyl 2,4,6-trimethylphenyl ketone
1-mesitylethan-1-one
1-acetyl-2,4,6-trimethylbenzene
MFCD00008735
J9E8ZRC2WE
51885-97-3
1-(2,4,6-trimethylphenyl)ethan-1-one
NSC-65636
1-(2,4,6-trimethyl-phenyl)-ethanone
1-(2,4,6-Trimethylphenyl)-1-ethanone
2-Acetylmesitylene
1-Mesitylethanone #
Methyl mesityl ketone
UNII-J9E8ZRC2WE
R1204
NCIOpen2_000113
2',6'-Trimethylacetophenone
SCHEMBL698413
2,4,6-Trimethyl-acetophenone
1,5-Trimethyl-2-acetylbenzene
Acetophenone,4',6'-trimethyl-
Ethanone,4,6-trimethylphenyl)-
acetophenone, 2,4,6-trimethyl-
Methyl 2,6-trimethylphenyl ketone
2',4', 6'-trimethylacetophenone
2',4',6'-trimethyl acetophenone
ALBB-022477
NSC65636
2', 4', 6'-trimethylacetophenone
(2',4',6'-Trimethyl)acetophenone
STL281391
1-(2,4,6-Trimethylphenyl)-ethanone
AKOS000120526
FT70931
Ethanone,1-(2,4,6-trimethylphenyl)-
s10572
AS-10615
BP-12622
SY008923
2',4',6'-Trimethylacetophenone, 97+%
DB-019843
DB-302838
CS-0074269
NS00025454
EN300-20900
2',4',6'-Trimethylacetophenone, >=98.0% (GC)
Q63396022
F2146-0688
2 inverted exclamation mark ,4 inverted exclamation mark ,6 inverted exclamation mark -Trimethylacetophenone