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DMPP

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Identification
Molecular formula
C11H17NO
CAS number
5908-79-6
IUPAC name
1-(2,6-dimethylphenoxy)propan-2-amine
State
State

DMPP is a liquid at room temperature.

Melting point (Celsius)
-10.00
Melting point (Kelvin)
263.15
Boiling point (Celsius)
217.50
Boiling point (Kelvin)
490.60
General information
Molecular weight
179.27g/mol
Molar mass
179.2760g/mol
Density
1.0201g/cm3
Appearence

DMPP is typically a colorless liquid.

Comment on solubility

Solubility of 1-(2,6-dimethylphenoxy)propan-2-amine (C11H17NO)

The solubility of 1-(2,6-dimethylphenoxy)propan-2-amine can be quite interesting due to its unique chemical structure. This compound features both hydrophobic and hydrophilic characteristics, which can influence its behavior in various solvents.

Factors Affecting Solubility

Several factors play a crucial role in determining the solubility of this compound:

  • Polarity: The presence of the amine functional group contributes to the polar nature of the molecule, enhancing solubility in polar solvents.
  • Hydrophobic Aromatic Ring: The 2,6-dimethylphenoxy group introduces hydrophobic characteristics, which can limit solubility in water.
  • Temperature: As with many compounds, an increase in temperature generally leads to increased solubility.

General Observations

In a typical scenario, one might observe:

  • Moderate solubility in water due to the polar amine group.
  • Higher solubility in organic solvents such as ethanol, methanol, or DMSO due to the hydrophobic properties associated with the rest of the molecule.

As a rule of thumb, compounds that contain both hydrophilic and hydrophobic regions tend to have a unique solubility profile that can be explored in various contexts. Understanding the solubility mechanics can facilitate effective usage in synthetic and analytical chemistry.

Interesting facts

Interesting Facts about 1-(2,6-Dimethylphenoxy)propan-2-amine

1-(2,6-Dimethylphenoxy)propan-2-amine, often abbreviated as DMAPA, is a fascinating organic compound that finds its applications primarily in the field of medicinal chemistry. Here are some key points that highlight its significance:

  • Structural Insight: The compound features a propan-2-amine backbone linked to a 2,6-dimethylphenoxy group. This unique structure contributes to its biological properties and potential efficacy in pharmaceuticals.
  • Biological Relevance: As an amine derivative, DMAPA may exhibit important interactions with neurotransmitter systems, making it a potential candidate for drugs targeting various neurological conditions.
  • Synthetic Utility: The amine functional group in DMAPA makes it a valuable intermediate for synthesizing more complex molecules, thus serving as a building block in organic synthesis.
  • Research Potential: Current studies focus on examining its therapeutic applications, including anti-depressant or anti-anxiety effects, owing to its ability to modulate neurotransmitter levels in the brain.
  • Safety First: Although many organic compounds can have beneficial effects, understanding the toxicological profile and safety aspects of DMAPA is essential in its development and usage.

In the words of renowned chemists, "The true beauty of organic compounds lies not only in their structure but in the vast potential they hold for advancing science and medicine." DMAPA exemplifies this notion, representing the intersection of organic chemistry and pharmacology.

As research continues to evolve, the full scope of 1-(2,6-dimethylphenoxy)propan-2-amine's contributions to science remains to be uncovered, emphasizing the importance of innovation in the field of chemistry.

Synonyms
Mexiletine
31828-71-4
1-(2,6-dimethylphenoxy)propan-2-amine
Mexiletina
1-(2,6-Dimethylphenoxy)-2-propanamine
2-Propanamine, 1-(2,6-dimethylphenoxy)-
Mexitil
Mexiletinum
dl-mexiletine
Mexiletinum [INN-Latin]
Mexiletina [INN-Spanish]
(RS)-Mexiletine
1-Methyl-2-(2,6-xylyloxy)ethylamine
1-(2,6-Dimethylphenoxy)-2-aminopropane
ETHYLAMINE, 1-METHYL-2-(2,6-XYLYLOXY)-
(+/-)-Mexiletine
1-(2',6'-Dimethylphenoxy)-2-aminopropane
EINECS 250-825-7
UNII-1U511HHV4Z
Mexiletine (INN)
1-methyl-2-(2,6-xylyloxy)ethanamine
BRN 2092205
1U511HHV4Z
CHEBI:6916
(2RS)-1-(2,6-dimethylphenoxy)-2-aminopropane
CHEMBL558
2-Amino-1-(2,6-dimethylphenoxy)propane
Mexilitine
DTXSID8048446
(+-)-1-(2,6-dimethylphenoxy)propan-2-amine
MEXILETINE [INN]
Mexiletinum (INN-Latin)
Mexiletina (INN-Spanish)
Mexiletine [INN:BAN]
(+/-)-2-AMINO-1-(2',6'-DIMETHYLPHENOXY)PROPANE
(2-((2,6-DIMETHYLPHENYL)OXY)-1-METHYLETHYL)AMINE
2-(2-aminopropoxy)-1,3-dimethylbenzene
NCGC00015659-06
Mexitil (Salt/Mix)
1-(2,4-Dimethylphenoxy)-2-propanamine
Spectrum_001602
MEXILETINE [MI]
1-(2,6-Dimethylphenoxy)-2-amino propane
Prestwick0_000241
Prestwick1_000241
Prestwick2_000241
Prestwick3_000241
Spectrum3_000727
Spectrum4_000795
Spectrum5_001279
MEXILETINE [VANDF]
MEXILETINE [WHO-DD]
Lopac0_000784
SCHEMBL16081
BSPBio_000022
BSPBio_002254
KBioGR_001270
KBioSS_002082
DivK1c_000834
SPBio_002241
BPBio1_000026
GTPL2629
DTXCID8028420
KBio1_000834
KBio2_002082
KBio2_004650
KBio2_007218
KBio3_001474
C01BB02
NINDS_000834
Mexiletine hydrochloride (Salt/Mix)
BDBM50117271
MFCD00792471
AKOS015890265
CCG-204869
DB00379
SB45974
SB45976
SDCCGSBI-0050762.P004
IDI1_000834
NCGC00015659-02
NCGC00015659-03
NCGC00015659-04
NCGC00015659-05
NCGC00015659-07
NCGC00015659-08
NCGC00015659-09
NCGC00015659-10
NCGC00015659-11
NCGC00015659-13
NCGC00015659-23
NCGC00162253-01
NCGC00162253-02
1-(2,6-dimethylphenoxy)-2-propanolamine
FM153231
SBI-0050762.P003
2-(2,6-dimethylphenoxy)-1-methylethylamine
AB00053683
NS00008331
2-(2,6-dimethylphenoxy)-1-methyl-ethylamine
EN300-54300
2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine
C07220
D08215
(+/-)-1-(2,6-dimethylphenoxy)propan-2-amine
AB00053683_10
AB00053683_11
Q420377
BRD-A64092382-003-04-3
BRD-A64092382-003-09-2
BRD-A64092382-003-16-7
BRD-A64092382-003-17-5
BRD-A64092382-003-18-3
2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine(Mexiletine)
2-(2-Aminopropoxy)-1,3-dimethylbenzene;1-(2,6-Dimethylphenoxy)-2-propanamine
250-825-7