Interesting facts
Compound Overview: 1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride
The compound 1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride is a fascinating substance that belongs to the class of amines and has a variety of applications, particularly in pharmaceutical chemistry.
Key Characteristics:
- Pharmaceutical Relevance: This compound is often found in research related to neuropharmacology and behavioral science, as it holds potential for developing new therapeutics.
- Functional Groups: The presence of both an aromatic ether and an amine functional group suggests interesting reactivity profiles. This makes it a compound of interest for synthetic chemists who are exploring new reaction pathways.
- Structural Variability: The 2,6-dimethyl substitution on the phenyl ring introduces steric hindrance, potentially influencing the compound's interaction with biological targets.
Research Applications:
Researchers are particularly interested in the compound for its potential therapeutic applications, including:
- Exploration of central nervous system (CNS) activity, given the amine group is often associated with neurotransmitter interactions.
- Investigation of its role as a precursor in the synthesis of related compounds with enhanced biological activity.
- Studying its pharmacokinetics and pharmacodynamics to understand its behavior in biological systems.
Did You Know?
As a hydrochloride salt, this compound is often more soluble in water compared to its free base form, enhancing its applicability in various biological assays. The ability to alter solubility is a crucial factor in drug design and development.
Moreover, the structural characteristics of this compound can lead to tailored modifications, paving the way for novel compounds with specific therapeutic targets.
In the words of a renowned chemist, “The beauty of chemistry resides in its ability to transform simple molecules into complex structures that can make profound impacts in the world around us.” This is particularly true for 1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride as it bridges the gap between basic research and therapeutic application.
Synonyms
Mexiletine hydrochloride
Mexiletine HCL
Katen
1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride
1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride
Ko 1173 Cl
2-Propanamine, 1-(2,6-dimethylphenoxy)-, hydrochloride
NSC-758639
KO-1173-Cl
KO-1173 CL
EINECS 226-362-1
606D60IS38
CHEBI:6917
UNII-606D60IS38
1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride
1-(2,6-Dimethylphenoxy)-2-aminopropane hydrochloride
NSC 758639
Ethylamine, 1-methyl-2-(2,6-xylyloxy)-, hydrochloride
(+-)-1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride
2-PROPANAMINE, 1-(2,6-DIMETHYLPHENOXY)-, HYDROCHLORIDE (1:1)
MEXILETINE HYDROCHLORIDE (MART.)
MEXILETINE HYDROCHLORIDE [MART.]
MEXILETINE HYDROCHLORIDE (USP-RS)
MEXILETINE HYDROCHLORIDE [USP-RS]
Mexiletine hydrochloride (USAN:USP:JAN)
Mexiletine hydrochloride [USAN:USP:JAN]
MEXILETINE HYDROCHLORIDE (EP MONOGRAPH)
MEXILETINE HYDROCHLORIDE (USP IMPURITY)
MEXILETINE HYDROCHLORIDE (USP MONOGRAPH)
MEXILETINE HYDROCHLORIDE [EP MONOGRAPH]
MEXILETINE HYDROCHLORIDE [USP IMPURITY]
MEXILETINE HYDROCHLORIDE [USP MONOGRAPH]
1-(2,6-dimethylphenoxy)propan-2-aminium chloride
2-Propanamine, 1-(2,6-dimethylphenoxy)-, hydrochloride, (+-)-
(1RS)-2-(2,6-Dimethylphenoxy)-1-methylethylamine monohydrochloride
5370-01-4
Mexitil
Mexiletene hydrochloride
Mexiletine (hydrochloride)
MFCD00216024
2-(2-aminopropoxy)-1,3-dimethylbenzene hydrochloride
1-Methyl-2-(2,6-xylyloxy)ethylammonium chloride
1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride
KOE-1173 (hydrochloride)
DTXSID2045783
1-(2,6-Xylyloxy)-2-aminopropane hydrochloride
1-(2,6-Dimethylphenoxy)-2-propylamine Hydrochloride
KO-1173
NCGC00094121-01
DTXCID0025783
SMR000326711
CAS-5370-01-4
SR-01000075986
NCGC00015659-06
(2S)-1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride
MFCD18379556
Prestwick_666
Mexitil (TN)
SCHEMBL42226
MLS001056756
MLS002222239
MLS002548872
SPECTRUM1503929
MEXILITENE HYDROCHLORIDE
Mexiletine hydrochloride, powder
CHEMBL1200606
HY-A0093R
HMS1568B04
Pharmakon1600-01503929
1-(2,6-Xylyloxy)-2-aminopropane
BCP28602
HY-A0093
Tox21_111249
Tox21_500784
KO1173
Mexiletine hydrochloride ( ge 98%)
Mexiletine hydrochloride ( ge 99%)
MEXILETINE HYDROCHLORIDE [MI]
NSC758639
s4225
Mexiletine hydrochloride (JP17/USP)
MEXILETINE HYDROCHLORIDE [JAN]
AKOS009139802
Mexiletine (hydrochloride) (Standard)
Tox21_111249_1
Tox21_111249_2
AC-4260
AC-8240
CCG-213246
FD25993
LP00784
MEXILETINE HYDROCHLORIDE [USAN]
NC00682
SB79359
MEXILETINE HYDROCHLORIDE [VANDF]
MEXILETINE HYDROCHLORIDE [WHO-DD]
NCGC00015659-14
NCGC00094121-02
NCGC00094121-03
NCGC00094121-04
NCGC00261469-01
5370-01-4 (HCl)
AS-13790
SY124361
1-(2,6-Dimethylphenoxy)-2-propanamine HCl
EU-0100784
M2040
SW196821-3
EN300-53944
MEXILETINE HYDROCHLORIDE [ORANGE BOOK]
D00639
M 2727
Mexiletine HCl;KO-1173; KO 1173; KO1173
SR-01000075986-1
SR-01000075986-6
Q27107357
Z2237335016
(S)-1-(2,6-Dimethylphenoxy)-2-propanamine Hydrochloride
1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride, 97%
(+/-)-1-METHYL-2-(2,6-XYLYLOXY)ETHYLAMINE HYDROCHLORIDE
2-PROPANAMINE, 1-(2,6-DIMETHYLPHENOXY)-, HYDROCHLORIDE, (+/-)-
Mexiletine hydrochloride, European Pharmacopoeia (EP) Reference Standard
Mexiletine hydrochloride, United States Pharmacopeia (USP) Reference Standard
Mexiletine hydrochloride;1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride;Katen
Solubility of 1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride
The solubility of 1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride is an important aspect to consider, as it directly affects its applications and biological activity. This compound is a salt form, which typically enhances its solubility in water compared to its corresponding free base.
Key points regarding its solubility include:
In summary, one could say that “the solubility of such ammonium salts can generally be exemplary for pharmaceutical applications, providing a favorable profile for interactions in biological systems.”
This characteristic makes 1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride a compound of interest in formulations requiring high solubility.