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Deferiprone

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Identification
Molecular formula
C7H9NO3
CAS number
30652-11-0
IUPAC name
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-hydroxy-pyridin-4-one
State
State

At room temperature, Deferiprone is typically found in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
272.50
Melting point (Kelvin)
545.65
Boiling point (Celsius)
223.00
Boiling point (Kelvin)
496.15
General information
Molecular weight
213.20g/mol
Molar mass
213.2160g/mol
Density
1.3900g/cm3
Appearence

Deferiprone appears as a white to off-white powder or crystalline solid. It is typically odorless.

Comment on solubility

Solubility of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-hydroxy-pyridin-4-one

This compound exhibits fascinating solubility characteristics that can be influenced by its unique molecular structure. Generally, the solubility of organic compounds such as this one can be assessed through several key factors:

  • Polarity: The presence of multiple hydroxyl groups contributes to its polar nature, which can increase solubility in polar solvents like water.
  • Hydrogen Bonding: The hydroxyl groups can form hydrogen bonds with solvent molecules, further enhancing solubility in suitable solvents.
  • pH Sensitivity: Being a pyridinone compound, its solubility may vary with pH changes, which can affect ionization and subsequent solubility.

The interplay of these factors makes it likely that this compound is more soluble in aqueous solutions and alcohols while presenting lower solubility in non-polar solvents. In practical applications, understanding the solubility can guide the formulation of drugs, where solubility plays a critical role in bioavailability. As expressed in a common adage in chemistry, "Like dissolves like." Therefore, this compound's solubility behavior emphasizes the importance of solvent choice in practical applications.

Overall, the intricate balance of structural features and environmental factors dictates the solubility of this interesting pyridinone compound.

Interesting facts

Interesting Facts About 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-hydroxy-pyridin-4-one

This fascinating compound presents a remarkable intersection of carbohydrate and heterocyclic chemistry. Not only does it incorporate elements of both sugar and aromatic functionalities, but it also illustrates the complexity of natural product synthesis.

Key Features

  • Biological Significance: Compounds similar to this one are often found in various biological systems, potentially playing key roles in biochemical pathways, particularly in metabolism and signaling.
  • Stereochemistry: The presence of multiple chiral centers in this compound highlights the importance of stereochemistry in determining biological activity and interactions. This allows scientists to explore the impact of spatial arrangement on function.
  • Potential Applications: Given its structural features, there is potential for this compound to be explored as a therapeutic agent. Its similarity to known bioactive molecules raises interest in its pharmacological properties.
  • Research Frontiers: The study of such compounds opens new avenues in medicinal chemistry, allowing for the design of novel compounds with targeted activity against diseases.

As noted by researchers, "Understanding the interplay between sugar moieties and aromatic systems can unlock new dimensions in drug discovery." This underscores the compound's relevance in synthetic and medicinal chemistry fields.

Overall, the intricate design of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-hydroxy-pyridin-4-one makes it a captivating subject for ongoing research and exploration!