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5-Iodouridine monohydrate

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Identification
Molecular formula
C9H11IN2O6
CAS number
320-40-1
IUPAC name
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione;hydrate
State
State

At room temperature, 5-Iodouridine monohydrate is in a solid state. It remains stable under standard atmospheric conditions without decomposing.

Melting point (Celsius)
218.00
Melting point (Kelvin)
491.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
384.10g/mol
Molar mass
384.0580g/mol
Density
2.3200g/cm3
Appearence

5-Iodouridine monohydrate appears as a white to off-white crystalline powder. The crystals are typically fine and exhibit a solid form under standard conditions.

Comment on solubility

Solubility of 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione; hydrate

The solubility of this compound can be described as quite complex, due in part to its multifaceted structure, which includes both hydrophilic and hydrophobic components.

  • Hydrophilic Characteristics: The presence of hydroxyl groups (–OH) increases the likelihood of the compound being soluble in polar solvents such as water.
  • Hydrophobic Regions: The inclusion of iodine in the structure may introduce some hydrophobic characteristics, potentially decreasing overall solubility in aqueous environments.
  • Hydrate Form: The fact that this compound is a hydrate suggests that it can interact favorably with water molecules, often leading to enhanced solubility due to its ability to form hydrogen bonds.

Therefore, while one might expect moderate solubility in water, it is essential to consider the solvent system and concentration. Additionally, properties such as temperature can significantly affect solubility. As it has been noted, "Solubility is not just a property but a complex interaction of molecular characteristics." Thus, predicting the solubility of this compound may require empirical evidence obtained through experimental methods.

Interesting facts

Interesting Facts about 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione; hydrate

This intriguing compound, often referred to in scientific literature due to its potential applications in pharmaceuticals, presents a fascinating structure that intertwines both carbohydrate and heterocyclic chemistry. Here are some noteworthy points:

  • Structural Complexity: The compound exhibits a unique combination of a pyrimidine ring and a tetrahydrofuran structure. This fusion of structural elements showcases the versatility of organic chemistry in creating complex molecules.
  • Biological Relevance: Compounds related to pyrimidines are often explored for their biological activity. They serve as essential building blocks in the synthesis of nucleic acids and have significant roles in cellular processes.
  • Hydroxy Functionality: The presence of hydroxy groups within its structure can enhance interactions with biological targets, making this compound a candidate for further exploration in medicinal chemistry.
  • Popularity in Research: As scientists search for new therapeutic agents, this compound may emerge as a focus due to its potential anti-viral or anti-cancer properties, aligning with the ongoing demand for innovative treatments.
  • Quote from a Chemist: "Nature's creativity in molecular design is unparalleled. Each compound holds a story waiting to be unraveled, and this one is no exception!"

In summary, 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione; hydrate is not just a molecule; it represents a crossroads of various scientific fields, highlighting the importance of interdisciplinary approaches in modern chemistry.

Synonyms
IDOXURIDINE MONOHYDRATE
17140-71-5
UNII-7E78KL7PVW
7E78KL7PVW
Uridine, 2'-deoxy-5-iodo-, monohydrate
DTXSID50169090
DTXCID3091581
Idoxuridine (hydrate)
5-Iodo-2'-deoxyuridine (hydrate)
orb1688543
HY-B0307A
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione,hydrate
1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1h,3h)-dione hydrate
DA-49040
CS-0009289
Q27268138
5-Iodo-2-deoxyuridine (hydrate);IdUrd (hydrate);5-IUdR (hydrate)
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione;hydrate