Interesting facts
Interesting Facts about 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
This fascinating compound, known for its intricate structure, has captured the interest of scientists in various fields due to its potential applications and unique properties. Here are some intriguing aspects worth noting:
- Structural Complexity: This compound features a pyrimidine ring fused with a dihydrofuran moiety, showcasing a remarkable interplay between different functional groups. The presence of a hydroxymethyl group adds to its potential reactivity.
- Biological Relevance: Compounds of this nature often serve as precursors for biologically active substances, opening possibilities in pharmacology and medicinal chemistry. Their structures may resemble key biologically active components, making them ideal candidates for drug discovery.
- Synthetic Pathways: The synthesis of this compound highlights the fascinating techniques within organic chemistry, where chemists often utilize multi-step reactions to obtain such complex structures.
- Research Applications: Given its unique characteristics, this compound could play a pivotal role in the development of agrochemicals and pharmaceuticals, particularly those targeting metabolic pathways in various organisms.
A chemist might conclude that understanding the properties and reactivity of 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione not only enhances our knowledge of chemical interactions but also provides vital insights into potential applications in medicine and agriculture. As the field evolves, the exploration of such compounds continues to unveil exciting prospects.
Synonyms
stavudine
3056-17-5
2',3'-Didehydro-3'-deoxythymidine
Estavudina
Stavudinum
Thymidine, 2',3'-didehydro-3'-deoxy-
Zerit Xr
d4T
3'-Deoxy-2'-thymidinene
2',3'-Didehydro-3'-deoxythimidine
Dideoxydidehydrothymidine
1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
Stavudine (d4T)
BO9LE4QFZF
Stavudine (dt4)
STV
NSC-759897
DTXSID1023819
CHEBI:63581
NSC-163661
DTXCID803819
NSC163661
1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
STAVUDINE (MART.)
STAVUDINE [MART.]
STAVUDINE (USP-RS)
STAVUDINE [USP-RS]
STAVUDINE (EP MONOGRAPH)
STAVUDINE [EP MONOGRAPH]
STAVUDINE (USP MONOGRAPH)
STAVUDINE [USP MONOGRAPH]
2',3' Didehydro 3' deoxythymidine
3'-deoxythymidin-2'-ene
Stavudin
2',3'-Didehydro-2',3'-dideoxythmidine
Didehydrodeoxythymidine
1-(2,3-dideoxy-beta-glycero-pent-2-enofuranosyl)thymine
sanilvudine
Zerit
BMY-27857
Stavudinum [INN-Latin]
Estavudina [INN-Spanish]
ddeThd
3'-Deoxy-2',3'-didehydrothymidine
BMY 27857
1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine
Sanilvudine (JAN)
CHEMBL991
Zerut XR
1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione
MLS000028546
D-4T
1-[(2R,5S)-5-(HYDROXYMETHYL)-2,5-DIHYDROFURAN-2-YL]-5-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE
NCGC00023212-07
SMR000058350
D 4T (nucleoside)
SANILVUDINE [JAN]
NSC 163661
Stavudine [USAN:BAN:INN]
1-(2,3-Dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine
D 4T
ddeTyd
MFCD00132921
1-(cis-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
220020-60-0
CAS-3056-17-5
Zerit(TM)
Zerit (TN)
HSDB 7338
SR-01000075802
UNII-BO9LE4QFZF
BMY27857
Stavudine (USAN/INN)
BRN 0618327
D4T & GM-CSF
2'-Thymidinene, 3'-deoxy-
Stavudine [USAN:USP:INN:BAN]
D4TMBY-27857-3
Stavudine (Standard)
STAVUDINE [INN]
STAVUDINE [MI]
STAVUDINE [HSDB]
STAVUDINE [USAN]
Opera_ID_1281
D 1413
cid_5155
STAVUDINE [WHO-DD]
STAVUDINE [WHO-IP]
1-((2R,5S)-5-Hydroxymethyl-2,5-dihydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione
3''-deoxy-2''-thymidine
Lopac0_000336
SCHEMBL38661
STAVUDINE [EMA EPAR]
cid_18283
MLS000759504
MLS001055348
MLS001077292
MLS001424091
MLS006011922
BIDD:GT0082
Stavudine - Bio-X trade mark
2',3'-Anhydrothymidine; d4T
STAVUDINE [EP IMPURITY]
STAVUDINE [ORANGE BOOK]
GTPL12678
HY-B0116R
1-(2,3-Dideoxy-beta-D-glycero-2-pentenofuranosyl)thymine
STAVUDINUM [WHO-IP LATIN]
HMS2051O20
HMS2234C10
HMS3039O05
HMS3259L21
HMS3261C13
HMS3428C07
HMS3714N22
Pharmakon1600-01502339
STAVUDINE (D4T) [VANDF]
STAVUDINE (DT4) [VANDF]
BCP02952
HY-B0116
Tox21_110886
Tox21_201393
Tox21_300583
Tox21_500336
BBL033763
BDBM50013111
NSC759897
STK801888
AKOS005622554
Tox21_110886_1
AC-5263
CCG-100902
CS-1872
DB00649
KS-1115
LP00336
NC00152
NC00684
ND07118
SDCCGSBI-0050324.P002
ZIDOVUDINE IMPURITY A [WHO-IP]
2'',3''-didehydro-3''-deoxythymidine
3''-deoxy-2'',3''-didehydrothymidine
3'-Deoxy-2',3'-didehydro-D-thymidine
NCGC00023212-03
NCGC00023212-04
NCGC00023212-05
NCGC00023212-08
NCGC00023212-09
NCGC00023212-10
NCGC00023212-11
NCGC00023212-12
NCGC00023212-13
NCGC00023212-14
NCGC00023212-25
NCGC00023212-30
NCGC00254372-01
NCGC00258944-01
NCGC00261021-01
Stavudine 100 microg/mL in Acetonitrile
1-[5-(hydroxymethyl)-2,5-dihydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione & Colony-stimulating factor 2
BD164571
SMR000673569
2',3'-didehydro-2',3'-dideoxythymidine
Thymidine, 2',3'-didehydro-, 3'-deoxy-
ZIDOVUDINE IMPURITY A [EP IMPURITY]
D3580
EU-0100336
NS00002353
2'',3''-dideoxy-2'',3''-didehydrothymidine
C07312
D00445
EN300-120634
AB00383018_18
Q423984
SR-01000075802-1
SR-01000075802-4
2',3'-Didehydro-3'-deoxythymidine, >=98% (TLC)
BRD-K93880783-001-26-6
Z1530425068
Stavudine, European Pharmacopoeia (EP) Reference Standard
Stavudine, United States Pharmacopeia (USP) Reference Standard
Thymine, 1-(2,3-dideoxy-beta-D-glycero-pent-2-enofuranosyl)-
1-(5-Hydroxymethyl-2,5-dihydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione
1-(5-Hydroxymethyl-2,5-dihydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (ddeThd)
3'- Azido-3'-deoxythymidine & Granulocyte-macrophage colony-stimulating factor
Stavudine for system suitability, European Pharmacopoeia (EP) Reference Standard
1-[(2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-(1H,3H)-dione
Sanilvudine;2',3'-Didehydro-2',3'-dideoxythymidine;3'-Deoxy-2',3'-didehydro-D-thymidine;2',3'-Didehydro-3'-deoxythymidine
Zidovudine Related Compound A;Sanilvudine;3'-Deoxy-2',3'-didehydro-D-thymidine;2',3'-Didehydro-3'-deoxythymidine
Solubility of 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
The solubility of this complex organic compound is influenced by several factors, primarily its molecular structure and functional groups. 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione features a pyrimidine ring with additional hydroxymethyl and furan-based functionalities that can engage in interactions with solvents.
Here are some key points regarding its solubility:
It’s important to note that specific experimental conditions, such as temperature and pH, will also play important roles in determining solubility. Understanding these interactions can significantly enhance the application and utilization of this compound in various chemical processes.