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N-Acetylserotonin

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Identification
Molecular formula
C12H14N2O2
CAS number
608-07-1
IUPAC name
1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone
State
State

At room temperature, N-Acetylserotonin is found in a solid state, typically as a crystalline powder.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.00
Boiling point (Celsius)
522.00
Boiling point (Kelvin)
795.00
General information
Molecular weight
218.27g/mol
Molar mass
218.2650g/mol
Density
1.2100g/cm3
Appearence

N-Acetylserotonin typically appears as an off-white to pale yellow powder or crystalline substance.

Comment on solubility

Solubility of 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone

The solubility of 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone in various solvents is an intriguing aspect of its chemical behavior. Several factors influence its solubility, including:

  • Polarity: Due to the presence of amino and indole functional groups, this compound is expected to exhibit moderate polarity, possibly enhancing solubility in polar solvents.
  • Hydrogen Bonding: The amino group can participate in hydrogen bonding, which may significantly increase solubility in water and alcohols.
  • Hydrophobic Interactions: The indole moiety can introduce hydrophobic characteristics, leading to varying solubility in different organic solvents.

Water Solubility: Results may vary, but the compound could be soluble to a certain extent in water, primarily due to the amino group. It’s essential to note that solubility can be affected by:

  • Temperature: Higher temperatures may increase solubility.
  • pH: Changes in pH can protonate or deprotonate the amino group, influencing solubility.

In Summary: The solubility of 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone is a multifaceted characteristic shaped by its functional groups, solvent interactions, and environmental conditions. Further experimental data would provide a clearer picture of its solubility profile across various solvents.

Interesting facts

Interesting Facts about 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone

The compound 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone is a fascinating molecule primarily due to its structural complexity and potential biological significance. Here are some intriguing aspects to consider:

  • Indole Derivative: The presence of the indole ring in this compound links it to a broad class of biologically active compounds often found in nature. Indoles are essential building blocks in many pharmaceuticals and natural products.
  • Potential Applications: Compounds with similar structures have been studied for their roles in anti-cancer and anti-inflammatory activities. This molecule could be a candidate for further research in medicinal chemistry.
  • Biological Relevance: The aminoethyl group introduces a functional interaction point that may enhance the biological activity, allowing for potential receptor interactions or enzyme modulations.
  • Synthetic Routes: From a synthetic perspective, creating this compound poses unique challenges and opportunities. Chemists may explore various methods for introducing the indole moiety and the ethylamine chain to achieve the desired functionality.
  • Research Potential: Ongoing research into similar compounds continues to unveil their potential in treating neurodegenerative disorders and as precursors for drug synthesis.

In summary, 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone is more than just a chemical formula; it embodies the intersection of synthetic chemistry and biological applications that can lead to meaningful discoveries.

Synonyms
Acetryptine
3551-18-6
Acetriptina
Acetryptine [INN]
1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone
W 2965 A
3-(2-Aminoethyl)indol-5-yl methyl ketone
N9VWZ34G5E
CHEMBL110317
W2965 A
W-2965-A
Acetryptin
Acetryptinum
1-(3-(2-aminoethyl)-1H-indol-5-yl)ethanone
Acetryptinum [INN-Latin]
UNII-N9VWZ34G5E
Acetriptina [INN-Spanish]
5-acetyltryptamine
SCHEMBL2734593
DTXSID90189015
5-acetyl-1H-indole-3-ethanamine
RAUGYAOLAMRLLZ-UHFFFAOYSA-N
BDBM50049085
AKOS022647301
DB-069224
NS00124897
1-[3-(2-Amino-ethyl)-1H-indol-5-yl]-ethanone
Q27284757