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Tryptamine Hydrochloride

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Identification
Molecular formula
C10H13ClN2O
CAS number
343-94-2
IUPAC name
1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone;hydrochloride
State
State

At room temperature, tryptamine hydrochloride is in a solid state. It is a dry powder and needs to be stored in an airtight container to prevent exposure to air and moisture, which may affect its stability.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
204.71g/mol
Molar mass
204.7070g/mol
Density
1.1760g/cm3
Appearence

Tryptamine hydrochloride appears as a white to off-white crystalline powder. It is generally odorless and can form crystalline needles depending on the method of crystallization. This compound is often used in research and is sensitive to light and moisture, which can cause it to degrade and change appearance.

Comment on solubility

Solubility of 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone;hydrochloride

The solubility of 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone;hydrochloride can be influenced by several factors, particularly its ionic nature as a hydrochloride salt. Generally, the solubility characteristics of such compounds can be summarized as follows:

  • Solvent Polarity: Being a hydrochloride salt, it is expected to be soluble in polar solvents such as water. The presence of the hydrochloride group enhances its affinity for polar solvents.
  • pH Influence: The solubility may vary significantly with pH. In acidic conditions, the hydrochloride form is favored, increasing solubility.
  • Temperature Dependence: Like many chemical compounds, increasing the temperature can enhance solubility. Heat typically increases the kinetic energy of molecules, allowing for better interaction with solvent molecules.
  • Concentration Effects: As the concentration of this compound in solution increases, one might see a limit where saturation occurs, beyond which solubility will not increase.

In conclusion, the solubility of 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone;hydrochloride is primarily influenced by its ionic nature and the medium in which it is present. To optimize its solubility, it is essential to consider factors such as solvent properties, environmental pH, and temperature. Overall, compounds of this nature tend to display favorable solubility profiles, especially in aqueous environments.

Interesting facts

Interesting Facts about 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone; hydrochloride

This intriguing compound, which belongs to the indole family, presents a unique blend of characteristics that make it notable in both research and application. Indoles are known for their diverse biological activities, and this particular derivative showcases the following points of interest:

  • Biological Significance: Compounds related to indoles are often linked with antibacterial, antifungal, and anticancer activities, making them valuable in pharmaceutical research.
  • Neuroscience Connections: Due to its aminoethyl side chain, this compound could have implications in neuropharmacology, as indole derivatives are often studied for their roles in neurotransmitter systems.
  • Synthetic Pathways: The synthesis of this compound is of particular interest to synthetic organic chemists due to the challenges and strategies involved in constructing the indole ring and side ammonoethyl chain.
  • Research Applications: As a hydrochloride salt, this compound is often easier to handle and analyze in laboratory settings, making it a potential candidate for drug formulation studies.

"The study of indole derivatives continues to reveal new biochemical pathways and therapeutic possibilities." - Renowned Organic Chemist

Overall, 1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone; hydrochloride is a fascinating compound that bridges synthetic chemistry, biology, and pharmacology, encouraging further exploration in these interconnected scientific fields.

Synonyms
4682-98-8
KETONE, 3-(2-AMINOETHYL)INDOL-5-YL METHYL, HYDROCHLORIDE
3-(2-Aminoethyl)indol-5-yl methyl ketone hydrochloride
5-Acetyl-3-(2-aminoethyl)indole hydrochloride
DTXSID60196953
DTXCID00119444
1-[3-(2-aminoethyl)-1H-indol-5-yl]ethanone hydrochloride