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Cariprazine

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Identification
Molecular formula
C21H33Cl3N6O
CAS number
1083076-69-0
IUPAC name
1-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ium-1-yl-piperidin-1-ium-4-carboxamide;dichloride
State
State

At room temperature, Cariprazine is in a solid state, usually found as a crystalline powder. This solid-state form is typically stable when stored under proper conditions.

Melting point (Celsius)
218.50
Melting point (Kelvin)
491.65
Boiling point (Celsius)
376.70
Boiling point (Kelvin)
649.85
General information
Molecular weight
458.48g/mol
Molar mass
458.0120g/mol
Density
1.1564g/cm3
Appearence

Cariprazine dichloride is typically described as a white to off-white solid powder. It is often used in its crystalline form and doesn't have any distinct characteristics in appearance that set it apart visually from many other medications in solid powder or pill form.

Comment on solubility

Solubility of 1-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ium-1-yl-piperidin-1-ium-4-carboxamide; dichloride

The solubility of this compound is influenced by its complex structure and the presence of multiple functional groups. Here are some key points to consider:

  • Ionic Nature: As a dichloride salt, the presence of chloride ions suggests that this compound may exhibit reasonable solubility in polar solvents, particularly water.
  • Hydrophilicity: The ionic piperidin-1-ium groups increase its hydrophilicity, which typically enhances solubility in aqueous solutions.
  • Altering Conditions: Factors such as pH and temperature can significantly affect solubility. For instance, an increase in temperature usually leads to greater solubility for many salts.
  • Solvent Compatibility: This compound may show varying solubility in different organic solvents, where polar protic solvents like methanol or ethanol might promote dissolution compared to non-polar solvents.

In summary, while the exact solubility value may vary based on the conditions applied, it can generally be expected that the compound would be soluble in polar solvents due to its ionic and hydrophilic nature. As the adage goes, "Like dissolves like", reinforcing the notion that polar solvents will be most effective for dissolving this ionic compound.

Interesting facts

Exploring the Multifaceted Compound: 1-[3-(2-chloro-5,6-dihydrobenzob[1]benzazepin-11-yl)propyl]-4-piperidin-1-ium-1-yl-piperidin-1-ium-4-carboxamide; dichloride

This compound, known for its intricate structure, opens the door to fascinating discussions in the realm of medicinal chemistry. Here are some noteworthy insights:

  • Structural Complexity: The compound showcases a unique structural arrangement, featuring multiple piperidine rings and an aromatic system. This complexity often correlates with intriguing bioactivity, as structures can influence interaction with biological targets.
  • Pharmacological Potential: Compounds with similar structures have been studied extensively for their potential therapeutic effects, especially in treating neurological disorders. The presence of both piperidine and benzene derivatives suggests possible interactions with neurotransmitter receptors.
  • Chlorine Substitution: The substitution of chlorine atoms in organic compounds often enhances their biological activity while influencing their solubility and permeability. This is a critical feature in drug design.
  • Potential Research Applications: The dichloride form of the compound indicates its utility in experimental settings. Research may focus on understanding its mechanisms of action, stability, and how it compares with other compounds in therapeutic efficacy.

As students and scientists investigate this compound, they can also explore the significance of its derivation. The dual piperidinyl and carboxamide components are particularly interesting for their role in forming hydrogen bonds—an essential factor in drug-receptor interactions. In summary, this compound not only serves as a promising candidate in drug discovery but also highlights the richness of chemistry as a field of ongoing exploration.

Synonyms
(1,4'-Bipiperidine)-4'-carboxamide, 1'-(3-(10,11-dihydro-3-chloro-5H-dibenz(b,f)azepin-5-yl)propyl)-, dihydrochloride