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Periciazine

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Identification
Molecular formula
C21H23ClN4O2S
CAS number
2622-26-6
IUPAC name
1-[3-(2-chlorophenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide
State
State

At room temperature, Periciazine is found as a solid.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.00
Boiling point (Celsius)
603.00
Boiling point (Kelvin)
876.00
General information
Molecular weight
447.95g/mol
Molar mass
447.0020g/mol
Density
1.2000g/cm3
Appearence

Periciazine appears as a yellow to orange solid that is typically crystalline in nature.

Comment on solubility

Solubility of 1-[3-(2-chlorophenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide

The solubility of 1-[3-(2-chlorophenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide can be quite intriguing due to its complex structure. When analyzing the solubility of this compound, several factors come into play:

  • Polarity: The presence of polar functional groups, such as the carboxamide, suggests that the compound may be soluble in polar solvents like water.
  • Hydrophobic Regions: The chlorophenothiazine moiety introduces significant hydrophobic characteristics, which could limit solubility in aqueous environments.
  • pH Dependency: The carboxamide group might also influence solubility through ionization, depending on the pH of the solution, potentially increasing solubility in alkaline conditions.
  • Solvent Interaction: Organic solvents such as ethanol or methanol may enhance solubility due to similar polar properties and the capability to disrupt hydrophobic interactions.

In conclusion, while 1-[3-(2-chlorophenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide may exhibit varied solubility profiles, its actual solubility will ultimately depend on the specific environmental conditions. As is often stated in chemistry, "the solvent plays a critical role in determining the solubility of a compound."

Interesting facts

Interesting Facts about 1-[3-(2-chlorophenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide

This complex organic compound represents a fascinating class of molecules known as piperidine derivatives, which have significant importance in medicinal chemistry.

  • Therapeutic Potential: This compound exhibits properties that could make it valuable in treating various psychiatric and neurological disorders. By interacting with specific neurotransmitter systems, it may have the potential to alleviate symptoms associated with conditions such as schizophrenia or mood disorders.
  • Structural Diversity: The presence of both piperidine and phenothiazine moieties in its structure contributes to its diversity. The unique combination enhances the compound's ability to modulate biological activity while providing a scaffold for further modifications.
  • Mechanism of Action: As a compound that interacts with dopamine and serotonin receptors, its mechanism of action is complex. Researchers are particularly interested in its affinity for these receptors, which can provide insights into potential therapeutic routes.
  • Research Potential: Scientists are continually investigating the potential applications of this compound in research settings, particularly in the fields of drug design and discovery, as its structural features can serve as a template for developing new pharmacotherapies.
  • Multi-Functional Group Chemistry: This compound encompasses several functional groups that contribute to its reactivity and interaction patterns, making it a key subject in studying structure-activity relationships (SAR).
  • Synthetic Challenges: The synthesis of 1-[3-(2-chlorophenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide can be quite challenging due to its complexity, which makes it an interesting target for synthetic chemists aiming to optimize production methods.

As we continue to explore the properties and functionality of such compounds, it opens doors to new discoveries in pharmaceuticals and understanding of biological systems. The journey of studying this fascinating molecule is a testament to the intricate relationship between structure and biological activity.