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Olanzapine

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Identification
Molecular formula
C17H20N4OS1
CAS number
132539-06-1
IUPAC name
1-[3-(2-methylphenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide
State
State

At room temperature, Olanzapine is in a solid state.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
607.50
Boiling point (Kelvin)
880.65
General information
Molecular weight
312.44g/mol
Molar mass
312.4390g/mol
Density
1.2550g/cm3
Appearence

Olanzapine appears as a yellow or white to off-white crystalline powder.

Comment on solubility

Solubility of 1-[3-(2-methylphenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide

The solubility of 1-[3-(2-methylphenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide can be influenced by several factors which are essential for understanding its behavior in different solvents:

  • Polarity: The compound contains both polar and nonpolar portions, which might affect solubility. In general, compounds with significant polar characteristics tend to be soluble in polar solvents, such as water.
  • Temperature Dependency: Solubility is often temperature-dependent. As the temperature increases, solubility in most solvents increases.
  • pH Levels: The ionization of functional groups can vary with pH, impacting solubility in aqueous solutions.
  • Semi-polar Solvents: The presence of phenothiazine moieties might render it more soluble in semi-polar solvents like *ethanol* or *chloroform* compared to completely nonpolar solvents.

Overall, while specific solubility data may vary, the presence of both aromatic systems and amine functionalities suggests potential for diverse solubility characteristics. As a general guideline, the compound may exhibit better solubility in organic solvents compared to water due to its complex structure. This indicates that experimenting with a variety of solvents might be necessary to fully understand its solubility profile.

Interesting facts

Interesting Facts about 1-[3-(2-methylphenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide

This compound, with its intricate structure, is a fascinating example of a synthetic pharmaceutical molecule that demonstrates the tremendous versatility found in organic chemistry. Here are some noteworthy aspects of this compound:

  • Pharmaceutical Potential: Many compounds of this type are investigated for their potential use as therapeutic agents, particularly in the field of neurology, because of their structures that suggest activity at various neurotransmitter receptors.
  • Structured Complexity: The presence of multiple functional groups and complex rings in its structure makes it a target for numerous synthetic pathways, showcasing the creativity and skill required in modern chemistry.
  • Structure-Activity Relationship (SAR): Chemists often study such compounds to understand how structural variations can affect biological activity, opening discussions on drug design and discovery.
  • Interdisciplinary Interest: This compound exemplifies the intersection of organic chemistry, medicinal chemistry, and pharmacology, emphasizing the collaborative nature of scientific research.

As a researcher or student diving into the world of chemical compounds, it's exhilarating to think about how this molecule—and many like it—could lead to breakthroughs in medical science. The potential ramifications of modifying just a single component of its structure can yield significantly different biological outcomes, underscoring the importance of precision in chemical synthesis.

In conclusion, 1-[3-(2-methylphenothiazin-10-yl)propyl]-4-(1-piperidyl)piperidine-4-carboxamide not only reflects complex organic chemistry but also the promising avenues for innovative treatments in the healthcare sector.