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Clonazolam

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Identification
Molecular formula
C17H12ClN5O2
CAS number
33887-07-3
IUPAC name
1-[3-[3-(2-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one
State
State

At room temperature, clonazolam is typically a solid, often in the form of a powder.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
452.70
Boiling point (Kelvin)
725.85
General information
Molecular weight
353.18g/mol
Molar mass
353.1840g/mol
Density
1.2435g/cm3
Appearence

Clonazolam is typically found in the form of a crystalline powder. It may appear as a white or off-white substance.

Comment on solubility

Solubility of 1-[3-[3-(2-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one

The solubility of 1-[3-[3-(2-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one presents a fascinating case for study due to its complex structure and functional groups.

To understand its solubility characteristics, consider the following factors:

  • Polarity: This compound contains polar functional groups, which can enhance its interaction with polar solvents like water.
  • Hydrophobic Regions: The presence of the 2-chlorophenyl group introduces hydrophobic characteristics, which may limit solubility in polar solvents.
  • pH Effects: Solubility can also be affected by the pH of the solution, particularly if any ionizable groups are present.
  • Solvent Interaction: The compatibility of the solvent with the compound's structure greatly influences solubility. Organic solvents like ethanol or dimethyl sulfoxide (DMSO) might show better solubility than water.

In summary, while solubility might not be straightforward to predict for 1-[3-[3-(2-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one, the overall picture reveals that solvent choice and molecular structure play crucial roles in determining its solubility behavior. Therefore, conducting solubility tests in various solvents is essential for building a comprehensive understanding of this compound's characteristics.

Interesting facts

Interesting Facts about 1-[3-[3-(2-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one

This compound, often highlighted in the realm of organic chemistry due to its unique structure and potential applications, presents a fascinating area of study for both students and professionals alike. Here are some intriguing aspects:

  • Complex Structure: The compound features a diazabicyclo structure, which indicates the presence of a bicyclic framework containing two nitrogen atoms. Such frameworks are pivotal in synthesizing various pharmaceuticals due to their ability to mimic natural compounds.
  • Substituent Influence: The presence of the 2-chlorophenyl group plays a crucial role in the compound's reactivity and biological properties. Substituents like these can greatly affect a molecule's polarity, solubility, and overall activity.
  • Potential Pharmacological Activities: Compounds with similar structural motifs have been studied for their therapeutic effects, particularly in neurological and psychological conditions. The diazabicyclo core is associated with potential binding affinities for various receptors in the brain.
  • Application in Synthesis: This compound's unique structural characteristics can serve as a versatile intermediate in organic synthesis. The ability to easily modify the substituents makes it an attractive candidate for designing new drugs.
  • Research and Development: Ongoing research is focused on exploring the full extent of this compound's properties, particularly in medicinal chemistry. Investigating the pharmacodynamics and pharmacokinetics can reveal its usefulness in treating a range of ailments.

Overall, the study of 1-[3-[3-(2-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one opens the door to a deeper understanding of chemical reactivity, biological interactions, and innovative therapeutic developments. As **future chemists**, students are encouraged to delve deeper into such compounds to unearth their potential benefits and applications.