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Citalopram Hydrobromide

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Identification
Molecular formula
C20H21ClN2O2
CAS number
59729-32-7
IUPAC name
1-[3-[3-(3-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one;hydrochloride
State
State

At room temperature, the compound is typically a solid.

Melting point (Celsius)
188.00
Melting point (Kelvin)
461.15
Boiling point (Celsius)
323.00
Boiling point (Kelvin)
596.15
General information
Molecular weight
324.88g/mol
Molar mass
324.8810g/mol
Density
1.2300g/cm3
Appearence
The compound appears as a white to off-white crystalline powder.
Comment on solubility

Solubility of 1-[3-[3-(3-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one;hydrochloride

The solubility of the compound 1-[3-[3-(3-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one; hydrochloride is an interesting aspect to consider due to its complex structure. Here are some important points regarding its solubility:

  • Hydrochloride Salt Form: As this compound is in the hydrochloride form, it typically demonstrates improved solubility in water compared to its free base form.
  • Polarity Considerations: The presence of polar functional groups, such as the hydrochloride, enhances its solubility in aqueous solutions.
  • Influence of Temperature: Like many compounds, its solubility could be affected by temperature; increasing temperature generally increases solubility.
  • pH Sensitivity: The solubility may also be influenced by the pH of its aqueous environment, with varying solubility in acidic versus basic conditions.

In summary, 1-[3-[3-(3-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one; hydrochloride is expected to be more soluble in water due to its salt form, and understanding its solubility profile can provide insights into its behavior in biological and chemical applications.

Interesting facts

Interesting Facts about 1-[3-[3-(3-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one; hydrochloride

This compound is a fascinating example of chemical complexity due to its unique structure, which incorporates a bicyclic system. The incorporation of a 3-chlorophenyl group enhances its biological activity, making it noteworthy in medicinal chemistry.

  • Pharmacological Significance: Compounds like this one are often investigated for their potential therapeutic effects. Research into bicyclic systems has suggested that they can mimic naturally occurring neurotransmitters.
  • Synthetic Routes: The synthesis of this compound involves intricate multi-step processes, showcasing the creativity and precision required in organic synthesis. Such compounds often serve as intermediates in drug development.
  • Diverse Applications: Beyond medicinal uses, compounds with similar structures are explored in various fields, including material sciences and biochemical research, due to their unique properties.
  • Research Implications: As a hydrochloride salt, it may exhibit improved solubility and stability, enhancing its feasibility for pharmaceutical formulations.

The study of 1-[3-[3-(3-chlorophenyl)allyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one; hydrochloride underscores the critical interplay between chemical structure and biological activity. As researchers continue to explore these relationships, such compounds pave the way for advancements in drug discovery and development.