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Curcumin

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Identification
Molecular formula
C21H20O6
CAS number
458-37-7
IUPAC name
1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-2,4,6-trihydroxy-5-methyl-phenyl]butan-1-one
State
State

Curcumin is typically found as a solid in the form of a crystalline powder at room temperature. It is commonly extracted from turmeric and used in various applications such as food coloring, dietary supplements, and traditional medicine.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
650.00
Boiling point (Kelvin)
923.15
General information
Molecular weight
368.39g/mol
Molar mass
368.3850g/mol
Density
1.3000g/cm3
Appearence

Curcumin is a bright yellow to orange crystalline powder. It has a distinctive color that is often used as a colorant in food and other applications. Curcumin exhibits polymorphism, meaning it can exist in multiple forms. The crystalline form is the most common state at room temperature, but it can show different appearances based on the physical state and purity.

Comment on solubility

Solubility of 1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-2,4,6-trihydroxy-5-methyl-phenyl]butan-1-one

The solubility of the chemical compound 1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-2,4,6-trihydroxy-5-methyl-phenyl]butan-1-one presents a complex profile influenced by its intricate structure. This compound features multiple functional groups that dictate its solubility behavior. Here are some key points to consider:

  • Polarity: Due to the presence of hydroxyl (-OH) groups, which are polar, the compound is likely to exhibit appreciable solubility in polar solvents such as water and alcohols.
  • Hydrophobic interactions: The butanoyl group and aromatic rings suggest hydrophobic characteristics, potentially decreasing solubility in highly polar environments.
  • Intramolecular hydrogen bonding: The dihydroxy groups may lead to intramolecular interactions that can stabilize the molecule, impacting overall solubility.
  • Solvent-specific solubility: As with many organic compounds, solubility may vary significantly depending on the solvent used, emphasizing the importance of solvent compatibility.

In conclusion, while the solubility of this compound can be deduced to some extent by analyzing its functional groups, it is important to conduct empirical solubility tests in various solvents to obtain accurate and practical insights. As the wise saying goes, "the solubility of a compound is as much about its environment as it is about its nature."

Interesting facts

Introduction to 1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-2,4,6-trihydroxy-5-methyl-phenyl]butan-1-one

This compound is a fascinating example of intricate organic chemistry, showcasing a complex structure that can be attributed to its extensive functional groups and multi-ring system. Here's a closer look at some interesting aspects of this molecule:

Key Features

  • Polyhydroxy Phenols: The compound exhibits multiple hydroxyl (-OH) groups, which contribute to its potential antioxidant properties. These groups can donate hydrogen to reactive radicals, helping to stabilize them.
  • Functional Diversity: The presence of both butanoyl and methoxy groups adds significant functional diversity, allowing for unique chemical reactivity and interactions with biological systems.
  • Potential Biological Activities: Compounds with similar structures have been studied for their roles in pharmacology. They may exhibit anti-inflammatory, analgesic, or even anticancer activities.

Chemical Interactions

The presence of multiple phenolic units suggests that this compound may readily participate in hydrogen bonding, which can affect solubility and reactivity. Furthermore, these interactions could enhance the compound's effectiveness in various applications, particularly in biochemistry.

Applications and Research

This compound is of great interest in the field of medicinal chemistry, where it may be explored for:

  • Development of new therapeutics targeting oxidative stress-related diseases.
  • Natural product synthesis due to its complex structure, which can serve as a lead for designing novel compounds.
  • Enhancing the efficacy of existing drugs by modifying its structure for better binding affinity.

Conclusion

1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-2,4,6-trihydroxy-5-methyl-phenyl]butan-1-one is more than just a complex organic compound; it embodies the intricate relationship between structure and function in chemistry. As research continues to unveil its properties and potential, this compound stands out as a promising subject for future scientific exploration.

Synonyms
Margaspidin
BRN 2067959
Butyrophenone, 2',2''',4',6',6'''-pentahydroxy-4'''-methoxy-3',3'''-methylenebis(5'-methyl-
DTXSID70171933
DTXCID7094424
qwrnqliwxknunm-uhfffaoysa-n
Margaspindin
Margaspidin BB
1867-82-9
1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methylphenyl)methyl]-2,4,6-trihydroxy-5-methylphenyl]butan-1-one
2',2''',4',6',6'''-Pentahydroxy-4'''-methoxy-3',3'''-methylenebis(5'-methylbutyrophenone)
1-[3-[[2,4-Dihydroxy-6-methoxy-5-methyl-3-(1-oxobutyl)phenyl]methyl]-2,4,6-trihydroxy-5-methylphenyl
1-[3-[(3-butanoyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-2,6-dihydroxy-4-methoxy-5-methylphenyl]butan-1-one
1-[3-(3-Butyryl-2,4-dihydroxy-6-methoxy-5-methylbenzyl)-2,4,6-trihydroxy-5-methylphenyl]-1-butanone #