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Curcumin

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Identification
Molecular formula
C21H20O6
CAS number
458-37-7
IUPAC name
1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-2,6-dihydroxy-4-methoxy-phenyl]butan-1-one
State
State

Curcumin is typically in a solid state at room temperature. It is slightly soluble in water, which can be a consideration when using it in various applications.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
570.00
Boiling point (Kelvin)
843.15
General information
Molecular weight
368.39g/mol
Molar mass
368.3850g/mol
Density
1.4300g/cm3
Appearence

Curcumin is a bright yellow crystalline solid. It is known for its vibrant coloration, which contributes to the yellow hue of turmeric. The compound may also appear as an amorphous yellow-orange powder when used in powdered form.

Comment on solubility

Solubility of 1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-2,6-dihydroxy-4-methoxy-phenyl]butan-1-one

This compound, with its complex structure, presents distinct solubility characteristics that are influenced by various factors. Understanding its solubility is crucial for determining its applications in chemical processes and formulations. Here are some points to consider:

  • Polarity: Given the presence of multiple hydroxyl (-OH) groups, the compound exhibits polar characteristics, suggesting potential solubility in polar solvents such as water or ethanol.
  • Hydrophobic Regions: The aromatic rings and butanoyl group introduce hydrophobic elements that may limit solubility in highly polar environments.
  • Solvent Compatibility: This compound is more likely to be soluble in organic solvents mixed with water, such as methanol or acetonitrile, rather than in pure water due to its structural complexity.
  • Temperature Influence: Solubility may also vary with temperature; typically, increasing temperature enhances solubility for many organic compounds.
  • Concentration Effects: In saturated solutions, the solubility limit might be reached quickly due to the balance of hydrophobic and hydrophilic interactions.

An interesting observation about solubility is that it can often be predicted based on the “like dissolves like” principle, where polar substances are soluble in polar solvents and non-polar substances are soluble in non-polar solvents. Thus, while this compound has the potential for decent solubility in specific environments, it is important to consider the solvent's properties and the overall composition of the solution. Further experimental data may be required to establish precise solubility values.

Interesting facts

Insights into 1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-2,6-dihydroxy-4-methoxy-phenyl]butan-1-one

This compound presents a fascinating structure that exemplifies the intricate chemistry found in organic compounds, particularly those with complex substitutions on aromatic rings. As a compound belonging to the class of flavonoids, it exhibits potential health-related benefits, prompting scientific interest in its properties and applications.

Notable Characteristics:

  • Potential Bioactivity: Compounds like this often show antioxidant, anti-inflammatory, or antimicrobial properties, making them valuable in the pharmaceutical industry.
  • Complex Structure: The presence of multiple hydroxyl groups and methoxy groups suggests that this compound could exhibit significant biological activity due to its ability to participate in hydrogen bonding and alter biological pathways.
  • Synthetic Pathways: Understanding the synthesis of such a compound can illuminate methods for creating structurally similar compounds, providing insights into drug design and the development of therapeutic agents.
  • Natural Sources: Often, compounds with similar backbones are derived from plants, which means this compound could also be explored in the context of traditional medicine and herbal studies.

Scientific Significance:

As a scientist or chemistry student, exploring compounds like 1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-2,6-dihydroxy-4-methoxy-phenyl]butan-1-one offers an opportunity to appreciate the vast diversity within chemical compounds. Furthermore, it allows for rich discussions regarding:

  • Structure-activity relationships (SAR) in pharmacology
  • The significance of functional groups in determining reactivity and stability
  • Implications for drug development and natural product chemistry

In summary, delving into the chemistry of this compound can yield exciting insights, highlight its potential applications, and inspire further exploration of similar multifaceted compounds in the field of chemistry.

Synonyms
Phloraspidinol
Phloraspidinol BB
1509-10-0
BUTYROPHENONE, 5'-METHYL-3',3'''-METHYLENEBIS(2',6'-DIHYDROXY-4'-METHOXY-
1-[3-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methylphenyl)methyl]-2,6-dihydroxy-4-methoxyphenyl]butan-1-one
1-[3-[[2,4-Dihydroxy-6-methoxy-5-methyl-3-(1-oxobutyl)phenyl]methyl]-2,6-dihydroxy-4-methoxyphenyl]-
BRN 2316058
DTXSID70164643
ABJZJBCLEZJOTC-UHFFFAOYSA-N
NS00094767
1-[3-(3-Butyryl-2,4-dihydroxy-6-methoxybenzyl)-2,6-dihydroxy-4-methoxy-5-methylphenyl]-1-butanone #