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Acridinium derivative

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Identification
Molecular formula
C28H36N4OCl2
CAS number
202842-98-6
IUPAC name
1-[3-(9,9-dimethylacridin-10-yl)propyl]-4-piperidin-1-ium-1-yl-piperidin-1-ium-4-carboxamide;dichloride
State
State

At room temperature, this compound is typically in a solid state. The solid may be powdered or in crystalline form, depending on the sample preparation and purity. It is usually stable in dry conditions but may absorb moisture from the air.

Melting point (Celsius)
286.50
Melting point (Kelvin)
559.65
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
518.44g/mol
Molar mass
518.4400g/mol
Density
1.2780g/cm3
Appearence

The compound is a crystalline solid that typically appears as a white to off-white powder. It is hygroscopic and may appear slightly yellow if impurities are present. Under standard conditions, the compound is stable and retains its structural integrity.

Comment on solubility

Solubility Characteristics

The solubility of the compound 1-[3-(9,9-dimethylacridin-10-yl)propyl]-4-piperidin-1-ium-1-yl-piperidin-1-ium-4-carboxamide; dichloride can be influenced by several factors. Here are key considerations:

  • Polar Nature: The presence of multiple piperidin-1-ium units and the carboxamide group suggests an overall polar character, which typically enhances solubility in polar solvents such as water.
  • Chloride Salts: As a dichloride salt, this compound may exhibit improved solubility compared to its neutral form due to ion-dipole interactions in aqueous solutions.
  • Temperature Influence: Solubility often increases with temperature; thus, the behavior of this compound at various temperatures may shed light on its solubility limits.
  • pH Sensitivity: The solubility might change drastically with pH, especially because of the piperidin-1-ium groups that can be protonated or deprotonated, affecting their solvation.

The compound is likely to display significant solubility in aqueous environments, making it practical for formulations in medicinal chemistry. Overall, the interplay of its polar functional groups and ionic nature is crucial in determining its solubility profile.

Interesting facts

Interesting Facts about 1-[3-(9,9-dimethylacridin-10-yl)propyl]-4-piperidin-1-ium-1-yl-piperidin-1-ium-4-carboxamide; dichloride

This intriguing compound, known for its complex structure, displays a fascinating interplay between organic chemistry and medicinal applications. Here are some noteworthy aspects:

  • Structure and Composition: The molecule features a unique combination of acridine and piperidine moieties, which are significant in various pharmacological contexts.
  • Potential Applications: Compounds like this one are often explored in the realm of antitumor therapies and other medicinal fields. The piperidine structure is particularly notable for its utility in drug design.
  • Research Interest: The compound has attracted attention due to its potential as a ligand in biochemical research. Its complex design makes it a subject of interest in studies related to receptor binding and molecular interactions.
  • Photophysical Properties: The 9,9-dimethylacridine component may impart unique photophysical properties to the compound, making it a candidate for photoactive materials in light-emitting applications.
  • Chemical Stability: Salts like the dichloride form often exhibit enhanced stability, which is an important parameter in the development and handling of pharmaceutical compounds.

The exploration of such complex compounds not only advances our understanding of chemical interactions but also opens new avenues in drug discovery and therapeutic chemistry. As research continues, methylated acridine derivatives like this one may pave the way for innovative treatments, making them a vibrant area of study in modern chemistry.

Synonyms
28058-63-1
9,9-Dimethyl-10-(3-(4-carbamoyl-4-piperidinopiperidino)propyl)acridan 2HCl hydrate
Isonipecotamide, 1-(3-(9,9-dimethyl-10-acridanyl)propyl)-4-piperidino-, hydrochloride, hydrate (4:8:1)
RefChem:349716