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2,4,6-Trihydroxyacetophenone

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Identification
Molecular formula
C8H8O4
CAS number
480-66-0
IUPAC name
1-(3-acetyl-2,4,6-trihydroxy-phenyl)ethanone
State
State

The compound is generally found as a solid at room temperature.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.00
Boiling point (Celsius)
403.00
Boiling point (Kelvin)
676.00
General information
Molecular weight
196.15g/mol
Molar mass
196.1680g/mol
Density
1.4133g/cm3
Appearence

2,4,6-Trihydroxyacetophenone is typically a crystalline solid and can be either white or slightly yellow in color. It has a characteristic phenolic odor.

Comment on solubility

Solubility of 1-(3-acetyl-2,4,6-trihydroxy-phenyl)ethanone

The solubility of 1-(3-acetyl-2,4,6-trihydroxy-phenyl)ethanone in various solvents can be influenced by several factors, considering its complex structure with multiple hydroxyl groups. Here are important points regarding its solubility:

  • Water Solubility: Due to the presence of three hydroxyl groups, the compound exhibits a degree of solubility in water. The hydrogen bonding capabilities of these hydroxyl groups enable interactions with water molecules, enhancing solubility.
  • Organic Solvents: The molecule may also dissolve well in organic solvents such as ethanol, methanol, and acetone. These solvents are typically polar, which aligns with the polarity of the hydroxyl groups.
  • Influence of Acetyl Group: The acetyl group attached to the aromatic ring can influence solubility, as it has a moderate ability to interact with different solvents. This may lead to variations in solubility depending on the solvent system used.
  • Cation Interaction: Cations could potentially form interactions with the hydroxyl groups, sometimes enhancing solubility in certain ionic solutions.

In summary, the solubility of 1-(3-acetyl-2,4,6-trihydroxy-phenyl)ethanone highlights a notable versatility, allowing it to dissolve in both polar and some non-polar environments, making it a compound of interest for various chemical applications. Understanding its solubility is crucial when considering its use in formulations and reactions.

Interesting facts

Exploring 1-(3-acetyl-2,4,6-trihydroxy-phenyl)ethanone

1-(3-acetyl-2,4,6-trihydroxy-phenyl)ethanone is a fascinating compound that belongs to the class of acetophenones, known for their diverse applications in various fields such as pharmacology and organic synthesis. Here are some noteworthy facts about this intriguing molecule:

  • Phenolic Richness: The compound features a trihydroxy substitution on the aromatic ring, which significantly enhances its antioxidant properties. This makes it particularly interesting in health and wellness applications.
  • Biological Activity: Studies reveal that compounds with phenolic structures often exhibit various biological activities, including anti-inflammatory and antimicrobial effects. Hence, this compound could be a candidate for further therapeutic development.
  • Synthetic Versatility: The acetyl group attached to the phenolic structure not only provides reactivity in further chemical modifications but also alters the compound’s solubility and stability, an essential characteristic for synthetic chemists.
  • Natural Sources: Compounds similar to this one have been successfully isolated from several plants, highlighting its potential as a natural product with beneficial properties.

As a molecule with complex chemistry, 1-(3-acetyl-2,4,6-trihydroxy-phenyl)ethanone opens up avenues for exploration, whether one is interested in organic synthesis, pharmacological studies, or natural product research. The continued investigation of its properties and potential applications could lead to groundbreaking discoveries in science and medicine.

Synonyms
2,4-Diacetylphloroglucinol
2161-86-6
diacetylphloroglucinol
1-(3-acetyl-2,4,6-trihydroxyphenyl)ethanone
CHEBI:78688
PHLOROGLUCINOL, DIACETYL-
8XV4YYO3WN
1,1'-(2,4,6-trihydroxy-1,3-phenylene)diethanone
UNII-8XV4YYO3WN
BRN 1881572
1,1'-(2,4,6-Trihydroxy-1,3-phenylene)bisethanone
Ethanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis-
DTXSID10175995
1,5-diacetyl-2,4,6-trihydroxybenzene
2,4,6-trihydroxy-1,3-diacetylbenzene
5-acetyl-2,4,6-trihydroxyacetophenone
4-08-00-03374 (Beilstein Handbook Reference)
2,4-diAc-phloroglucinol
2,4-DAPG
DTXCID9098486
Ethanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis-(9CI)
piffqyjynwxnge-uhfffaoysa-n
1-(3-acetyl-2,4,6-trihydroxyphenyl)ethan-1-one
2,4-Diacetyl Phloroglucinol
CHEMBL276139
IPO 15474FS
1-(3-acetyl-2,4,6-trihydroxy-phenyl)ethanone
MFCD00100483
DAPG
MLS000877011
MEGxm0_000280
SCHEMBL1258932
ACon1_000673
HMS2271L07
2,4-Diacetylbenzene-1,3,5-triol
BDBM50456593
AKOS022649955
AD21440
NCGC00169471-01
K-2
PD017283
SMR000440689
DB-025479
HY-118448
CS-0065976
C21896
G77934
Q4596777
1,1-(2,4,6-trihydroxy-1,3-phenylene)bis-ethanone
1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis(ethan-1-one)
1,1'-(2,4,6-Trihydroxy-1,3-phenylene)bis-ethanone;1,3-Diacetyl-2,4,6-trihydroxybenzene;5-Acetyl-2,4,6-trihydroxyacetophenone