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3'-Aminoacetophenone

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Identification
Molecular formula
C8H9NO
CAS number
99-03-6
IUPAC name
1-(3-aminophenyl)ethanone
State
State

At room temperature, 3'-Aminoacetophenone is typically in a solid state, with a crystalline powder texture.

Melting point (Celsius)
83.00
Melting point (Kelvin)
356.15
Boiling point (Celsius)
291.00
Boiling point (Kelvin)
564.15
General information
Molecular weight
135.17g/mol
Molar mass
135.1650g/mol
Density
1.0770g/cm3
Appearence

3'-Aminoacetophenone appears as off-white to beige crystals or powder. It may also appear as pale yellow or tan, depending on the level of impurities present.

Comment on solubility

Solubility of 1-(3-aminophenyl)ethanone

1-(3-aminophenyl)ethanone, also known as 3-aminoacetophenone, presents unique characteristics regarding its solubility:

  • Solubility in Water: This compound exhibits limited solubility in water due to the hydrophobic nature of the aromatic ring, which hinders the formation of strong interactions with water molecules.
  • Solubility in Organic Solvents: It is significantly more soluble in organic solvents such as ethanol, acetone, and dichloromethane. This solubility pattern is indicative of its relatively non-polar structure.
  • Influence of pH: The presence of the amino group may allow for some degree of protonation and increased solubility in acidic conditions, although this effect is generally modest.
  • Temperature Effects: Like many organic compounds, an increase in temperature can enhance solubility, making it easier to dissolve in organic solvents.

As a general observation, the solubility of 1-(3-aminophenyl)ethanone highlights the importance of understanding intermolecular interactions, which can be categorized as:

  • Hydrophobic interactions with non-polar solvents.
  • Hydrogen bonding potential with polar solvents under specific conditions.

In conclusion, while 1-(3-aminophenyl)ethanone may not be readily soluble in water, its behavior in organic solvents provides valuable insights into its potential applications in various chemical processes. Understanding these solubility characteristics is crucial for designing effective formulations and conducting chemical reactions.

Interesting facts

Exploring 1-(3-aminophenyl)ethanone

1-(3-aminophenyl)ethanone, often referred to as a derivative of acetophenone, is a fascinating organic compound that serves as a prime example of how functional groups affect chemical properties and reactivity.

Interesting Facts:

  • Structure and Functional Groups: This compound features both an amine and a ketone functional group, a combination that provides it with unique reactivity. The presence of the amino group enhances its potential to participate in various chemical reactions, including nucleophilic substitutions.
  • Applications in Synthesis: 1-(3-aminophenyl)ethanone is significant in the synthesis of pharmaceuticals and other organic materials. It acts as an intermediate in the production of complex molecules, making it valuable in medicinal chemistry.
  • Biological Relevance: Due to its structural components, the compound may exhibit biological activity. Many amine-containing compounds are known for their roles in medicinal chemistry, leading to potential applications in drug development.
  • Analytical Interest: The compound can be monitored and studied using various analytical techniques, such as NMR and mass spectrometry, allowing researchers to understand its properties, behavior, and interactions with other molecules.
  • Research Potential: Given its unique structure, 1-(3-aminophenyl)ethanone is an intriguing subject in various fields, including material science, organic synthesis, and biological research.

In summary, 1-(3-aminophenyl)ethanone is not just a simple organic compound, but a vital piece in the puzzle of organic chemistry, with implications and applications that span across multiple disciplines. Its intriguing structure and potential make it a noteworthy subject for further exploration!

Synonyms
3'-Aminoacetophenone
1-(3-Aminophenyl)ethanone
99-03-6
3-AMINOACETOPHENONE
3-Acetylaniline
m-Aminoacetophenone
Ethanone, 1-(3-aminophenyl)-
m-Acetylaniline
1-(3-aminophenyl)ethan-1-one
m-Aminoacetylbenzene
Acetophenone, 3'-amino-
Acetophenone, m-amino-
3-Aminoacetofenon
NSC 7637
3-aminoacetophenon
EINECS 202-722-3
MFCD00007796
3-Acetylphenylamine
BRN 0386009
meta-aminoacetophenone
AI3-14674
.beta.-Aminoacetophenone
ACETOPHENONE,3-AMINO
1-(3-amino-phenyl)-ethanone
CHEMBL3408644
DTXSID0021830
4-14-00-00096 (Beilstein Handbook Reference)
NSC-7637
beta-Aminoacetophenone
3-Aminoacetofenon [Czech]
3-acetyl-phenylamine
3-amino acetophenone
aniline, 3-acetyl-
3'-Amino-acetophenone
WLN: ZR CV1
1-(3-aminophenyl)-ethanone
3'-Aminoacetophenone, 97%
SCHEMBL330495
DTXCID601830
H366ULD45X
NSC7637
CHEBI:182866
STR02986
BDBM50546257
STL168894
AKOS000119494
CS-W013353
FA34420
HY-W012637
SY001475
DB-029992
A0249
NS00010817
3 inverted exclamation mark -Aminoacetophenone
3 inverted exclamation marka-Aminoacetophenone
EN300-17986
m-Aminoacetophenone;1-(3-Aminophenyl)ethanone
D70852
Q27453668
Z57127443
F2146-0312
202-722-3
3AO