Skip to main content

1-(3-Aminophenyl)pyridin-2-one

ADVERTISEMENT
Identification
Molecular formula
C11H10N2O
CAS number
3096-56-8
IUPAC name
1-(3-aminophenyl)pyridin-2-one
State
State
Solid at room temperature. Compounds like these are often used in organic synthesis or for pharmaceutical research.
Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
373.00
Boiling point (Kelvin)
646.15
General information
Molecular weight
184.21g/mol
Molar mass
184.2060g/mol
Density
1.2600g/cm3
Appearence

1-(3-Aminophenyl)pyridin-2-one typically appears as a crystalline solid. The compound may exhibit hues typical for organic amines, generally appearing as pale yellow to off-white crystals.

Comment on solubility

Solubility of 1-(3-aminophenyl)pyridin-2-one

The solubility of 1-(3-aminophenyl)pyridin-2-one can be influenced by several factors, such as temperature, pH, and the presence of other solutes in the solution. Generally speaking, this compound exhibits varying degrees of solubility in different solvents:

  • Water: It shows limited solubility in water, which could be attributed to its relatively hydrophobic structure.
  • Organic solvents: It is more soluble in organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO), making these solvents preferable for dissolving the compound in laboratory settings.
  • pH dependency: The solubility can also change with pH. The presence of the amino group can lead to protonation under acidic conditions, potentially increasing solubility.

In conclusion, the solubility characteristics of 1-(3-aminophenyl)pyridin-2-one highlight its versatility in different environments. Understanding these variations is essential for effective application in synthesis and biological studies. As with many organic compounds, the choice of solvent can critically affect its solubility, thus one should choose an appropriate solvent based on the specific requirements of the experiment or application.

Interesting facts

Interesting Facts About 1-(3-Aminophenyl)pyridin-2-one

1-(3-Aminophenyl)pyridin-2-one is an intriguing compound that belongs to a class of chemicals known for their diverse applications in medicinal chemistry and biologically active compounds. Here are some notable facts:

  • Biological Activity: This compound exhibits potential biological activity, making it a subject of interest in pharmacological studies. Research has shown it may possess anti-cancer and anti-inflammatory properties.
  • Chemical Structure: The unique structural features of 1-(3-aminophenyl)pyridin-2-one contribute to its reactivity and synergy with biological targets. The incorporation of an amino group significantly influences its interaction with enzymes and receptors.
  • Research Applications: Scientists are exploring the use of this compound in the development of novel therapeutics and diagnostic agents. The ability to modify its structure can lead to a range of derivatives with enhanced efficacy.
  • Synthesis: The synthesis of 1-(3-aminophenyl)pyridin-2-one can involve approaches such as multicomponent reactions and heterocyclic synthesis, making it an exciting topic for organic chemists aiming for innovative methodologies.

In summary, 1-(3-aminophenyl)pyridin-2-one is more than just a compound; it represents a frontier in the study of medicinal chemistry. Its potential applications highlight the importance of exploring new chemical entities for therapeutic purposes.

Synonyms
AMPHENIDONE
134-37-2
Dornwal
Amfenidona
Amphenidone [INN]
Aminophenylpyridone
Amphenidonum
1-(m-Aminophenyl)-2(1H)-pyridone
1-(3-Aminophenyl)-2-pyridone
Amfenidona [INN-Spanish]
Amphenidonum [INN-Latin]
1-(3-aminophenyl)pyridin-2-one
1-m-Aminophenyl-2-pyridone
UNII-M61FM2VCSV
M61FM2VCSV
BRN 1526918
1-(3-Aminophenyl)-2-(1H)-pyridinone
1-(m-Aminofenylo)-2-pirydonu
1-(m-Aminofenylo)-2-pirydonu [Polish]
AMPHENIDONE [MI]
2(1H)-Pyridone, 1-(m-aminophenyl)-
DTXSID50158449
5-21-07-00122 (Beilstein Handbook Reference)
Amfenidona (INN-Spanish)
Amphenidonum (INN-Latin)
1-(3-AMINOPHENYL)-2(1H)-PYRIDINONE
SCHEMBL586236
CHEMBL2104057
DTXCID1080940
CHEBI:134830
ZVSGUZQJNXHNIL-UHFFFAOYSA-N
AKOS006273137
NS00010471
Q27283535